Gene Information

Name : apxIIID (APJL_1344)
Accession : YP_001652344.1
Strain : Actinobacillus pleuropneumoniae JL03
Genome accession: NC_010278
Putative virulence/resistance : Virulence
Product : RTX-III toxin determinant D
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1566
EC number : -
Position : 1474432 - 1475865 bp
Length : 1434 bp
Strand : -
Note : -

DNA sequence :
ATGAAGTTATGGATTCTAGGACTTGGGGAATTTTTTCAACGTTATCGTAATATTTGGCGTGAAATATGGAAAATCCGCAA
ACAATTAGATACCCCAGCAAGACAAAAAGATGAAAACGAATTTTTGCCTGCGCATTTAGAGTTAATTGAGACACCTATTT
CAAAAAAGCCACGGCTGATCGCTTATTTGATAATGCTATTTCTATTTTTAGCTATTGTAATTTCCATTATTAGTAAAGTA
GAAATTGTTGCTAGTGCTACAGGTAAGTTGGTATTTAGTGGACATAGTAAAGAAATAAAGCCTATTGAGAATGCTTTAGT
AAAAGACATTTTTGTTAAAGATGGACAATTTGTTGAAAAAGGACAATTATTATTAAATCTCACCGCACTTGGTGCCGATG
CAGACAAACAAAAAACTAAAGTATCGTTAGGATTGGAAAGATTAGATGGTTACCGATATAAGTCATTGTTATATAGCATT
GAACACAATAGATTACCTTTATTGGATTTTAACCAAGCTGATTTTGATTCTGTTCAGGAAGAAGATAAGACTAACGCACG
TCATTTAATTACCGAACAATTTGAGACTTGGCAAAAACAAAAATATCAGAAGGAATTAGCGTATCAACGTAAACAAGCTG
AAAAACAAACAGTATTAGCAAATATCCGTAAATATGAAAGCGCTAGTCGTATTGAAAAGGAGAAATTAAGTGATTTAAAA
AAATTATATGATGTAAAGTCTATTTCTAAGCATGAGTTGTTAGCACAAGAAAATAGATATGTTGAAGCTAGTAATGAATT
GTCTGTTTATCAATCTCATCTCAAAGAAGTAGAAAGTGACTTGCTTAAAGCACAAGAAGATTTAAAGCTTGTTACTCAAT
TATTTAAGAGTGATATTTTGGAAAAACTACAGCAAAATATACAACGCGAAAAGCAGCTCACTTTAGAACTTGAGAAAAAT
GAACAACGTCAATTAGCCTCTATCATTAGGGCGCCAGTATCAGGCACAGTCCAACAATTAAAAACTCATACTAAAGGTGG
CGTAGTAACTACTGCAGAAACCTTAATGGTCATTGCTCCTGAGGATGACGTGTTGGAAGTAAGTGCTTTAATTCAAAACA
AAGATATTGGTTTTGTTGAAATTGGACAGGAAGCAGTTATTAAAGTGGAAACTTTTCCCTACACAAGATATGGTTATCTC
TATGGAAAAGTAAAAACTATTACTCTTGATGCTATTGAGCACCCTCAGCTTGGTTTAGTTTTCAATTCTATTATTGAGAT
TAATAAGAAAACATTAACAGATGGTGATAAAGAAATTCAATTAGGTTCCGGAATGAGCGTTATTGCAGAAATTAAAACAG
GAGAACGCAGTGTTATCAGTTTCCTACTCAGTCCATTAGAAGAATCTATTACTGAAAGTCTAAGAGAACGTTAA

Protein sequence :
MKLWILGLGEFFQRYRNIWREIWKIRKQLDTPARQKDENEFLPAHLELIETPISKKPRLIAYLIMLFLFLAIVISIISKV
EIVASATGKLVFSGHSKEIKPIENALVKDIFVKDGQFVEKGQLLLNLTALGADADKQKTKVSLGLERLDGYRYKSLLYSI
EHNRLPLLDFNQADFDSVQEEDKTNARHLITEQFETWQKQKYQKELAYQRKQAEKQTVLANIRKYESASRIEKEKLSDLK
KLYDVKSISKHELLAQENRYVEASNELSVYQSHLKEVESDLLKAQEDLKLVTQLFKSDILEKLQQNIQREKQLTLELEKN
EQRQLASIIRAPVSGTVQQLKTHTKGGVVTTAETLMVIAPEDDVLEVSALIQNKDIGFVEIGQEAVIKVETFPYTRYGYL
YGKVKTITLDAIEHPQLGLVFNSIIEINKKTLTDGDKEIQLGSGMSVIAEIKTGERSVISFLLSPLEESITESLRER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 8e-141 63
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 4e-141 63
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 6e-141 63
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 4e-126 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
apxIIID YP_001652344.1 RTX-III toxin determinant D VFG1556 Protein 2e-141 63
apxIIID YP_001652344.1 RTX-III toxin determinant D VFG0908 Protein 3e-141 63
apxIIID YP_001652344.1 RTX-III toxin determinant D VFG1502 Protein 5e-141 63
apxIIID YP_001652344.1 RTX-III toxin determinant D VFG0843 Protein 4e-101 48