Gene Information

Name : BcerKBAB4_4914 (BcerKBAB4_4914)
Accession : YP_001647690.1
Strain : Bacillus weihenstephanensis KBAB4
Genome accession: NC_010184
Putative virulence/resistance : Virulence
Product : Thiol-activated cytolysin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4875636 - 4877174 bp
Length : 1539 bp
Strand : -
Note : PFAM: Thiol-activated cytolysin; KEGG: bce:BC5101 perfringolysin O precursor

DNA sequence :
GTGATTTTTCTGAATATTAAGAAAAACACTAAAAGAAGAAAGTTCCTTACATGTTTATTAGTTAGTCTATGCACTATTAA
TTATTCATCTATTTCCTTCGCAGAAACACAAGTAGGTAATGCAACTGATGTAACCAAAAATGCTAGTGGCATTGATACTG
GTATAGCAAATCTTAAATATAATAATCAAGAGGTTTTAGCTGTAAATGGTGATAAGGTAGAGAGTTTTGTTCCGAAAGAA
AGTATCAATTCAAATGGTAAATTTGTAGTAGTGGAACGCGAGAAAAAATCACTTACAACTTCACCAGTCGATATTTCGAT
TATTGATTCTGTGGTGAATCGTACGTATCCAGGAGCGGTACAACTTGCAAATAAAGCTTTTGCAGACAATCAACCGAGTT
TATTAGTGGCTAAGAGAAAGCCTTTGAATATTAGTATAGACTTACCTGGCATGAGAAAAGAAAATACAATTACTGTCCAG
AATCCGACATATGGTAATGTGGCTGGAGCAGTAGATGATTTAGTATCTACTTGGAATGAAAAGTATTCTAAAACACATAC
GTTACCTGCAAGAATGCAGTATACAGAATCTATGGTTTATAGTAAATCACAAATCGCAAGTGCCCTTAACGTTAACGCTA
AATATCTCGATAACAGTCTAAACATCGATTTTAATGCGGTTGCAAATGGAGAGAAGAAAGTGATGGTAGCGGCATATAAG
CAAATATTTTATACCGTAAGTGCTGAACTACCTAACAATCCATCCGATCTTTTTGATAATAGTGTTACTTTTGGTGAGTT
AACTCGTAAAGGTGTAAGTAATTCGGCTCCACCTGTTATGGTCTCAAATGTAGCTTATGGTAGAACTGTTTATGTAAAAT
TAGAAACAACATCTAAGAGCAAAGATGTACAAGCTGCTTTTAAAGCCTTACTTAAGAATAACAGCGTCGAAACGAGTGGA
CAGTACAAAGATATTTTTGAAGAAAGTACTTTTACTGCTGTAGTATTAGGCGGAGATGCGAAAGAGCATAACAAGGTTGT
TACTAAAGATTTCAATGAAATCCGAAATATCATTAAAGATAATGCTGAATTAAGTCTTAAAAATCCAGCATATCCAATTT
CATATACAAGCACTTTCTTAAAAGATAATGCAACTGCTGCTGTTCATAACAATACAGATTATATTGAGACGACAACTACA
GAATATTCAAGTGCTAAAATGACACTTGATCATTACGGTGCTTATGTTGCTCAATTTGATGTATCTTGGGATGAATTCAC
ATTTGATCAAAATGGGAAAGAAGTACTAACACATAAAACATGGGATGGTAGCGGCAGAGACAAAACAGCTCATTACTCTA
CAGTTATCCCTTTTCCACCAAATTCAAAAAATATAAAAATCGTAGCTAGAGAATGTACTGGTCTTGCATGGGAATGGTGG
AGAACAATTATTAATGAACAAAATGTTCCATTAACAAATGAAATAAAAGTTTCAATTGGAGGAACAACATTATACCCAAC
TGCTAGTATTAGTCATTAG

Protein sequence :
MIFLNIKKNTKRRKFLTCLLVSLCTINYSSISFAETQVGNATDVTKNASGIDTGIANLKYNNQEVLAVNGDKVESFVPKE
SINSNGKFVVVEREKKSLTTSPVDISIIDSVVNRTYPGAVQLANKAFADNQPSLLVAKRKPLNISIDLPGMRKENTITVQ
NPTYGNVAGAVDDLVSTWNEKYSKTHTLPARMQYTESMVYSKSQIASALNVNAKYLDNSLNIDFNAVANGEKKVMVAAYK
QIFYTVSAELPNNPSDLFDNSVTFGELTRKGVSNSAPPVMVSNVAYGRTVYVKLETTSKSKDVQAAFKALLKNNSVETSG
QYKDIFEESTFTAVVLGGDAKEHNKVVTKDFNEIRNIIKDNAELSLKNPAYPISYTSTFLKDNATAAVHNNTDYIETTTT
EYSSAKMTLDHYGAYVAQFDVSWDEFTFDQNGKEVLTHKTWDGSGRDKTAHYSTVIPFPPNSKNIKIVARECTGLAWEWW
RTIINEQNVPLTNEIKVSIGGTTLYPTASISH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 6e-150 63
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 3e-100 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BcerKBAB4_4914 YP_001647690.1 Thiol-activated cytolysin VFG2275 Protein 5e-174 70
BcerKBAB4_4914 YP_001647690.1 Thiol-activated cytolysin VFG0976 Protein 2e-150 64
BcerKBAB4_4914 YP_001647690.1 Thiol-activated cytolysin VFG1363 Protein 2e-101 43
BcerKBAB4_4914 YP_001647690.1 Thiol-activated cytolysin VFG0074 Protein 3e-100 43