Gene Information

Name : BcerKBAB4_0390 (BcerKBAB4_0390)
Accession : YP_001643284.1
Strain : Bacillus weihenstephanensis KBAB4
Genome accession: NC_010184
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 448947 - 450872 bp
Length : 1926 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: bca:BC

DNA sequence :
ATGAACGCAGAAGTAAAAACATTACAAGCACAAAAAGATATTTCTAATCCCTCTTTATGGGATACATTAAAGAAACATTA
TGAACTTATATTTGCAATCGCATCTGGTATTTTTATTTTAGCTGGTTGGTTATTCACAAAAAATGATGTAATAAGTGCAG
GTATTACTTTATATATCCTTGCTTATGTAATTGGAGGATTTGCAAAAGCGAAAGAAGGTATTGAAGACACAATTGAAGAG
AAAGAGCTAAATGTTGAAATGCTCATGATTTTTGCAGCTATCGGTGCCGCAGTTATTGGTTACTGGGCAGAGGGTGCTAT
TTTAATCTTCATCTTTGCATTAAGCGGAGCAATGGAATCTTATACATTAAGTAAAAGCCAAAAAGAAATTTCAGCGCTTC
TTGATCTACAACCTGAAGAAGCATTACGTATTTCAAACGGAATTGAGGAACGTGTTCCAGTTGAACAATTACAAATTAAC
GATATTATTTTAATTAAGCCAGGTGAGCGTGTTCCTGCTGATGGCACTATTCATACTGGTGAAACAAATATTGATGAAGC
TGCTATTACAGGAGAACCCATTCCGAATGAGAAAAAATTCGGCGATGAAGTATTTGCCGGCACTGTAAATTTACGTGGTG
CTATTGAAGTTAAAATTACGAAGCCGAGCGATCAAACATTATTCCAAAAGATTATTCGTCTCGTTCAAAGTGCACAAAGC
GAAAAATCCCCATCACAACTATTCATCGAAAAATTTGAAGGAACATACGTAAAAGGTGTACTACTTGTTGTTGCGCTTAT
GATGTTTGTTCCTCATTTCTTACTTGATTGGAGTTGGAATGAAACGTTTTATCGCGCGATGATTTTACTTGTAGTCGCTT
CTCCTTGTGCGCTAGTTGCAGCCATTACACCGGCCACTTTATCAGCAATTTCAAACGGAGCGAGAAACGGTATTCTCTTT
AAAGGTGGTATTCATTTAGAACGTCTAGCTTCAGTAAAGGCGATTGCCTTTGATAAAACAGGAACATTAACACAAGGAAA
ACCTACTGTAACAGATGTATATGTTCGAGAAGGCATAGCAGAAAGTGAAGTACTTTCTATTACAGCAGCGATTGAAAGTC
ACTCTACACATCCTTTAGCAGAAGCGATTGTTAAATATGCAAAACATGCTTACGACATTACGATAAAAAAACCAGAAAAC
GTTGAAGATGTAACTGGTTTTGGATTAAAAGGAATATTAGAAAACAAATCTTATAAAATTGGTAAAGCTGATTTTATTGG
AGAAGAAACAAAGACATTTCATAATGGCATTTCTGCTTCACTTGAAAAAGAGGGGAAAACTGTCGTTTATATTAGTGATG
AGGATGGTATTCTTGGACTGATCGCTTTAAAAGATACCCTTCGCCAAGAAACGATAGCGGCTATTCGTGATTTGCAAAGC
ATTGGTGTCGAAGCAATCATGATTACTGGTGATAATGAAGAAACAGCAAAAGCAATTGCCAATGAAAGTAATATAAAAGA
ATATTACGCATCATGTTTACCGGAAACAAAAGTTGAAACGATAAAGCAGTTAAAAGAAAAGTACGGCATAGTCGCCATGG
TTGGAGATGGTATAAACGATGCACCTGCACTCGCTACTTCTAGTATTGGTGTTGCAATGGGTGAAGGAACAGACGTAGCA
TTAGAGACTGCAGACGTTGTTCTTATGAAAAACGAATTATCTCGTCTCTCTCAAGCAATCCGTTTATCAAAACGAATGAA
CCGTATTGTGAAGCAAAACGTTATCTTCTCTTTAGCTGTCATTGCAATGCTGATTTGTTCTAATTTCTTGCAGTTTTTAG
CTCTTCCATTCGGTGTTATTGGACATGAAGGAAGTACCATTCTTGTAATCTTGAATGGCTTACGATTATTAAAAGGAAAT
AAGTAA

Protein sequence :
MNAEVKTLQAQKDISNPSLWDTLKKHYELIFAIASGIFILAGWLFTKNDVISAGITLYILAYVIGGFAKAKEGIEDTIEE
KELNVEMLMIFAAIGAAVIGYWAEGAILIFIFALSGAMESYTLSKSQKEISALLDLQPEEALRISNGIEERVPVEQLQIN
DIILIKPGERVPADGTIHTGETNIDEAAITGEPIPNEKKFGDEVFAGTVNLRGAIEVKITKPSDQTLFQKIIRLVQSAQS
EKSPSQLFIEKFEGTYVKGVLLVVALMMFVPHFLLDWSWNETFYRAMILLVVASPCALVAAITPATLSAISNGARNGILF
KGGIHLERLASVKAIAFDKTGTLTQGKPTVTDVYVREGIAESEVLSITAAIESHSTHPLAEAIVKYAKHAYDITIKKPEN
VEDVTGFGLKGILENKSYKIGKADFIGEETKTFHNGISASLEKEGKTVVYISDEDGILGLIALKDTLRQETIAAIRDLQS
IGVEAIMITGDNEETAKAIANESNIKEYYASCLPETKVETIKQLKEKYGIVAMVGDGINDAPALATSSIGVAMGEGTDVA
LETADVVLMKNELSRLSQAIRLSKRMNRIVKQNVIFSLAVIAMLICSNFLQFLALPFGVIGHEGSTILVILNGLRLLKGN
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 8e-112 42
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 7e-112 42
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 7e-103 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-101 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 8e-102 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BcerKBAB4_0390 YP_001643284.1 heavy metal translocating P-type ATPase BAC0092 Protein 5e-136 48
BcerKBAB4_0390 YP_001643284.1 heavy metal translocating P-type ATPase BAC0124 Protein 3e-90 41