Gene Information

Name : guaA (BcerKBAB4_0247)
Accession : YP_001643143.1
Strain : Bacillus weihenstephanensis KBAB4
Genome accession: NC_010184
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 262485 - 264023 bp
Length : 1539 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGAAGAAGCAGCATGATACAATTATCGTTTTAGATTTTGGGAGTCAGTACAATCAGTTAATAGCACGTCGAATTCGTGA
GTTCGGTGTATACAGTGAACTTCATCCACATACAATTACTGCAGAAGAAATTAAAGCAATGAATCCAAAAGGGATTATCT
TCTCTGGTGGACCAAATAGTGTATACGGTGAAGGCGCATTACATTGTGATGAAAAAATCTTTGAACTAGGATTACCGATC
TTCGGTATTTGTTACGGTATGCAGCTTATGACACAACACTTCGGTGGTAAAGTAGAACGTGCAAACCACCGTGAGTATGG
AAAAGCTGTTCTTAAAGTAGAGAACGAATCAAAATTATATGCGAACCTTCCAGAAGAGCAAGTTGTATGGATGAGCCATG
GTGACTTAGTAACTGGTTTACCTGAAGGATTCGTAGTAGATGCAACAAGTGAGTCTTGTCCAATTGCTGGTATGAGCAAT
GAAGGGGAAAACTTATACGGTGTACAATTCCACCCAGAAGTACGTCACTCTGAGCACGGAAACGATTTAATTAAAAACTT
CGTATTCGGCGTATGTGGTTGTTCTGAAGGATGGAACATGGAGAACTTTATCGAAGTAGAATTAGAGAAGATCCGTGAAA
CTGTTGGAGACAAAAAAGTATTATGCGCACTTAGTGGTGGTGTAGACTCTTCTGTTGTAGCAGTATTAATTCATAAAGCG
ATTGGTGACCAATTAACATGTATTTTCGTGGACCACGGTTTACTTCGTAAAGATGAAGCAGAAGGTGTTATGAAAACATT
TAGCGAAGGCTTCCATATGAACGTTATTAAAGTGGATGCACAAGAGCGCTTCATGAACAAGTTAAAAGGTGTAGAAGATC
CAGAGCAAAAACGTAAAATCATCGGTAATGAATTCATTTACGTATTTGATGATGAAGCTTCTAAATTACAAGGAATGGAC
TTCCTAGCGCAAGGTACACTTTACACGGACATCGTTGAAAGTGGTACAGCAACTGCACAAACAATTAAATCTCACCATAA
CGTTGGTGGACTTCCAGAAGACATGCAGTTCAAATTAATTGAGCCTTTAAATACTTTATTTAAAGACGAAGTACGTGTAT
TAGGATCAGAACTAGGAATTCCTGATGAAATCGTATGGCGTCAACCGTTCCCAGGTCCAGGACTTGGTATTCGTGTATTA
GGTGAAATTACAGAAGAGAAATTAGAAATCGTTCGTGAATCTGATGCAATTTTACGTGAAGAAATTATAAAAGCAGGATT
AGACCGCGAAGTTTGGCAATACTTCACTGCGCTTCCTGGTATGCGTAGCGTAGGTGTTATGGGTGACGAGCGTACTTACG
ATTACACAGTAGGTATCCGTGCAGTAACATCTATCGATGGTATGACAGCTGACTGGGCACGTATCCCTTGGGACGTATTA
GAGAAAATCTCTGTACGTATCGTAAACGAAGTAAAACACGTTAACCGTATCGTGTATGATATAACGAGTAAGCCACCAGC
AACTATTGAGTGGGAATAG

Protein sequence :
MKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFELGLPI
FGICYGMQLMTQHFGGKVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAGMSN
EGENLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLIHKA
IGDQLTCIFVDHGLLRKDEAEGVMKTFSEGFHMNVIKVDAQERFMNKLKGVEDPEQKRKIIGNEFIYVFDDEASKLQGMD
FLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGIRVL
GEITEEKLEIVRESDAILREEIIKAGLDREVWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPWDVL
EKISVRIVNEVKHVNRIVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-138 54