Gene Information

Name : BcerKBAB4_2222 (BcerKBAB4_2222)
Accession : YP_001645070.1
Strain : Bacillus weihenstephanensis KBAB4
Genome accession: NC_010184
Putative virulence/resistance : Resistance
Product : chloramphenicol O-acetyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG4845
EC number : 2.3.1.28
Position : 2288697 - 2289341 bp
Length : 645 bp
Strand : +
Note : PFAM: chloramphenicol acetyltransferase; KEGG: btk:BT9727_2179 chloramphenicol O-acetyltransferase

DNA sequence :
ATGAAGTTTCATGTAATTGACAGAGAAAATTGGAATAGAGAGCAGTATTTTGAACATTATTTAAAATTAAAGTGTTCGTT
TAGTATGACAGCGAATGTTGATATTACGATGATGCTAGAGGAAATACATCAAAAGGAAATTAAATTTTATCCGACTTTTA
TTTATGTAATTTCTAGAGTGATAAATAAACATACAGAATTTCGAACATGTTTTAATGATGAAGGAGTTTTAGGGTATTGG
GAGGAAATGATACCTAGTTATACAATCTTTCATAAAGATAATAAATCTTTTTCAAGTATATGGACGGATTATTCTAGCGA
TTTCCACATTTTCTATAAAAACTATGAAGAGGATATGAGATGTTATGCTAATGTTCATGGTTTCTTCACGAAAGAAAATA
TTCCACCAAATATTTTTCCGATTTCTGGTATACCTTGGACTAGTTTTACAGGATTTAATTTAAATATTAATAATGATGGT
GATTCTTTATTACCAATTATTACTTGTGGAAAATATTTCAATGATGGAAGCAGGGTTATGCTACCTGTTTCATTGCAAGT
ACATCATGCGGTTTGTGATGGATATCATGCGAGTCGATTTATAGAGGATTTACAGGAGCTAGCTAATACTTGTAACCTTA
AGTAA

Protein sequence :
MKFHVIDRENWNREQYFEHYLKLKCSFSMTANVDITMMLEEIHQKEIKFYPTFIYVISRVINKHTEFRTCFNDEGVLGYW
EEMIPSYTIFHKDNKSFSSIWTDYSSDFHIFYKNYEEDMRCYANVHGFFTKENIPPNIFPISGIPWTSFTGFNLNINNDG
DSLLPIITCGKYFNDGSRVMLPVSLQVHHAVCDGYHASRFIEDLQELANTCNLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
catA2 ACF06176.1 chloramphenicol acetyltransferase II Not tested Tn5036-like Protein 2e-42 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BcerKBAB4_2222 YP_001645070.1 chloramphenicol O-acetyltransferase CP001581.1.gene2168. Protein 4e-58 55
BcerKBAB4_2222 YP_001645070.1 chloramphenicol O-acetyltransferase NC_010427.6155852.p0 Protein 5e-50 51
BcerKBAB4_2222 YP_001645070.1 chloramphenicol O-acetyltransferase NC_010426.6155849.p0 Protein 5e-50 51
BcerKBAB4_2222 YP_001645070.1 chloramphenicol O-acetyltransferase NC_010111.5787932.p0 Protein 1e-51 45
BcerKBAB4_2222 YP_001645070.1 chloramphenicol O-acetyltransferase CP004022.1.gene799.p Protein 2e-45 44