Gene Information

Name : thyA (BcerKBAB4_2061)
Accession : YP_001644914.1
Strain : Bacillus weihenstephanensis KBAB4
Genome accession: NC_010184
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2123752 - 2124708 bp
Length : 957 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACATGCTGAATATGAATACTTAAATTTATGCCGTCATGTAATGGAGCACGGTACGAAGAAAGAAGATCGTACAGG
GACAGGTACTGTATCTGTATTTGGATATCAAATGCGTTTCGATCTAAGTAAAGGATTTCCTTTATTAACGACAAAGAGAG
TGCCATTTCGCCTAGTAGCAAGTGAACTGCTTTGGTTTATGAAAGGTGATACAAATATTCGTTATTTATTGCAACATAAT
AATAATATTTGGAATGAATGGGCGTTTAAGAGCTGGGTAGAAAGCGATGAGTATACTGGCCCTGATATGACAGATTTCGG
TCTTCGCTCACAACAAGATGAGGAATTTAAAGTGCAGTACGATGAGCAAATGGAATTGTTTAAAAAGAACGTTTTAGAAG
ACGATGAATTCTCAACGAAATTTGGATATTTAGGAGACGTATACGGAAAGCAGTGGCGTGCTTGGAAAACGACAGCTGGT
GAGACACTTGATCAATTAAAAGATGTAATTGAAATGATTAAGAAAACACCAGATTCACGCCGTCTAATTGTGTCTGCTTG
GAATCCTGAAGATGTACCAAGTATGGCTTTACCGCCTTGTCATACGCTATTCCAGTTTTATGTAGCAGATGGAAAGCTTT
CTTGTCAGTTATATCAGAGAAGCGGTGACATATTCCTTGGCATTCCATTTAACATTGCAAGCTATTCACTTTTAACACAT
TTAATTGCACATGAATGTGGTCTTGAAGTAGGAGAGTTTGTTCATACAATTGGAGATGCACACATTTATACAAATCATTT
TGAACAAGTAGAAAAGCAATTGGCACGTGAACCACGCCCGTTCCCTAAACTTACATTAAATCCAGATGTGAAATCTGTGT
TTGATTTTGAGATGGAAGATTTAACGATTGAAGGATATGATCCACACCCAGCGATTAAAGCACCGGTTGCAGTGTAA

Protein sequence :
MKHAEYEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHN
NNIWNEWAFKSWVESDEYTGPDMTDFGLRSQQDEEFKVQYDEQMELFKKNVLEDDEFSTKFGYLGDVYGKQWRAWKTTAG
ETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPSMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTH
LIAHECGLEVGEFVHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 5e-105 66