Gene Information

Name : guaA (Caur_0973)
Accession : YP_001634594.1
Strain : Chloroflexus aurantiacus J-10-fl
Genome accession: NC_010175
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1349636 - 1351177 bp
Length : 1542 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCACACACAGCATACCGGTACTGGATTTTGGTTCGCAAACCGCTCAGCTCATCGTGCGGCGGTTGCGTGAGCTAGG
CTACTACAGCGAGTTATTACCACACGACGCCCCCGAAGATCAGGTGCGAGCGCTGGCGCCGGTTGGTATTGTACTCAGCG
GTGGCCCGGCAAGTGTCTACGAACCTGGCGCCCCTACGCTCCCGTCGTGGTTGCTGGAGAGTGATCTACCGGTCTTCGGT
ATCTGCTACGGTATGCAACTAATCAGCCACACCCTGGGCGGGATTGTCACCCGGCCGGCTGGCCGCGAATACGGCCCGGC
GATGATCACCATCACTCATCCGCACCCCCTCTTCGCCGACACCCCAACCGAGCAACCGGTCTGGATGAGCCACGGTGATC
GGATCGAACAGTTGCCCACCGGCTTCACAGCGATTGCTGCCAATCCGGCAACCCCCTTCGCCGCCATTGCTGATGATCGG
CGCAAGTGGTATGGTGTTCAGTTTCACCCCGAAGTGGTGCATACCGTCTATGGCCGAACCATCCTGACCAACTTTGCCCG
TCTGTGTGGGGCACGCCCTGAATGGCAACCGAACAGCTTCGTCGCCGAAGCCATCGAGCGGGTCAAAGCCCAGGTCGGCG
ATCACGGGCGCGTTATCTGTGCGTTGTCTGGCGGTGTCGACTCAGCCGTGGCCGCGCTCATTATTCATCGCGCTATCGGC
GACCGCCTGACCTGCGTCTTTGTTGATAATGGTCTGTTACGGGCAGGCGAAGCGGAACAGGTGATCGCTACCTTCAGCGA
GCATTTTCACGTGCCGCTGATTGCGGTTGATGCCCGCGAAGAGTTTATGACCGCTCTGAAAGGGGTGACTGACCCCGAAC
AGAAGCGCAAAATTATCGGCGAGAAATTCATTCGGATCTTCGAGCGTGAAGCCCGCGCCCTCGCCGGGGTTGAATTCCTC
GCCCAGGGCACTCTCTACCCCGACGTCATCGAGTCGACAGCCCCCGACCGCCCAAAGGCGGCGAAAATTAAAACCCACCA
TAATGTTGGCGGTCTACCAGCCGACATGCAGCTCAAACTGGTCGAGCCGCTGCGCTATCTGTTCAAAGACGAAGTACGCG
CCGCTGGCTTACAACTCGGGCTGCCCGAAACGTGGGTCTGGCGCCATCCCTTCCCTGGGCCGGGGCTGGCAGTGCGTATT
ATCGGTGAAGTAACCTGGGAGCGCCTGGAGATACTGCGGCAGGCGGATAAGATCTTTTTGGAAGAGTTGCATGCCAGTGG
CTATTATCGCGCCACCCAGCAGGCGTTTGCCGTCCTGCTACCGGTACAGAGTGTGGGGGTGATGGGTGATGGTCGTACCT
ACGGCGTCACGATTGCCTTGCGCGCGATTACGACCGAAGACTACATGACCGCCGACTGGGCACGTCTGCCTTACGAGCTG
CTGGCCCACGTGAGCAGCCGCATCGTCAACGAAGTCGAAGGGGTCAATCGGGTTGTGTACGATATTTCGTCGAAGCCACC
GGCAACTATCGAATGGGAGTAG

Protein sequence :
MTTHSIPVLDFGSQTAQLIVRRLRELGYYSELLPHDAPEDQVRALAPVGIVLSGGPASVYEPGAPTLPSWLLESDLPVFG
ICYGMQLISHTLGGIVTRPAGREYGPAMITITHPHPLFADTPTEQPVWMSHGDRIEQLPTGFTAIAANPATPFAAIADDR
RKWYGVQFHPEVVHTVYGRTILTNFARLCGARPEWQPNSFVAEAIERVKAQVGDHGRVICALSGGVDSAVAALIIHRAIG
DRLTCVFVDNGLLRAGEAEQVIATFSEHFHVPLIAVDAREEFMTALKGVTDPEQKRKIIGEKFIRIFEREARALAGVEFL
AQGTLYPDVIESTAPDRPKAAKIKTHHNVGGLPADMQLKLVEPLRYLFKDEVRAAGLQLGLPETWVWRHPFPGPGLAVRI
IGEVTWERLEILRQADKIFLEELHASGYYRATQQAFAVLLPVQSVGVMGDGRTYGVTIALRAITTEDYMTADWARLPYEL
LAHVSSRIVNEVEGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-135 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-134 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-135 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-124 54