Gene Information

Name : smpB (Caur_3317)
Accession : YP_001636893.1
Strain : Chloroflexus aurantiacus J-10-fl
Genome accession: NC_010175
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 4444768 - 4445250 bp
Length : 483 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
GTGACAGCAACAAAACACAAACACCCTGGTGTGGTCGCCGAGAACCGTAAGGCGCGCCACGATTACGATATTGAAGAGAC
GATTGAAGCGGGCATTGTCCTCTCCGGCAGCGAAATTAAATCGGTGCGCGCCGGACGGGTCAACTTGCGCGGCAGTTTTG
CCCGTGTGATCGATGATGAAGTGTTCCTGTATGATGCCCACATTGCGCCTTACGAGCAGTCGGGCAAATACTTCAACCAC
GATCCGATGCGTCCGCGCAAACTGCTGCTGCACCGACGTGAAATCAACCGCCTCAATGGCCTGGTGCGCATGAAGGGGAT
GACCCTGGTGCCGCTGAAGGTCTATTTCAAAGGACGCCGGGCTAAAGTTGAGCTTGGTGTAGCACGTGGGAAGAAGATCT
ACGATAAGCGCGAGGATATTGCCCGGCGCGATGCGGCCCGTGATATTGATCGGGCCTTGAAACGGGCAAGACACGATCTG
TAA

Protein sequence :
MTATKHKHPGVVAENRKARHDYDIEETIEAGIVLSGSEIKSVRAGRVNLRGSFARVIDDEVFLYDAHIAPYEQSGKYFNH
DPMRPRKLLLHRREINRLNGLVRMKGMTLVPLKVYFKGRRAKVELGVARGKKIYDKREDIARRDAARDIDRALKRARHDL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 5e-32 61
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 5e-27 52
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 2e-20 42