Gene Information

Name : lysS (Caur_1226)
Accession : YP_001634844.1
Strain : Chloroflexus aurantiacus J-10-fl
Genome accession: NC_010175
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1713827 - 1715302 bp
Length : 1476 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGAATTGAATGATTTACAGGCCCAACGTGCGGCAAAGCTGGCCGAATTGCGTGCTGCCGGTCTCGATCCATACCCACC
TCGCTGTTACCGCAGCCATACCATTGCCGAAGCTCTGGCTGCGTTTGATGATCTGGTCGCCCAGTCCACCACACTGACGC
TGACCGGACGCATCATCGGCGCTCGCCGCATTATGGGTAAGATCGCCTTTGCTCATATTGAAGATGGCACGGGTGAGATT
CAGCTCTGGCTCAGCCGGGCCGATCTCGGTGATGAATGGTTCGAGCGTTTTCGCGATCAGCTCGACACCTTCGATATTGT
CCAGGCGAGTGGTGTATTACGTTGCACCAAGACCGGTGAACGCTCGCTCTTTGTGCGTGAGCTGGCAATACTGGCCAAGG
CGATTAATCCACCCCCTGAAAAATGGGCCGGTTTGCAAGATGTCGAAGAGCGCCATCGCCAGCGCTATCTCGACCTGATC
GTTAACCGTGACCGCCGCGAGATTTTCCGGGCGCGGGCCCGTGTCATCAGCACGATGCGGCGCGTCCTGGATGAACGGGG
CTTTCTCGAAGTTGAGACACCGGTGTTGCAACCACTCTACGGTGGGGCTGCTGCACGCCCTTTTATCACCTATCACAATG
CGCTGGGCCAGAATCTCTATTTGCGGATCGCCACCGAACTCTACCTCAAGCGCCTGATTGTCGGCGGCTTTCCCGGTGTG
TACGAAATCGGGAAGAACTTTCGCAATGAAGGGGTTGATCGCTCACACAATCCAGAGTTCACCATGATGGAATGTTATCA
GGCGTATGCTGATTATCACGCCATGATGACTCTGGTGGAAGAGATGCTGAGCGAGATTTGTCTGGCTGTCCACGGCACCA
CAACGATCACCTATCAGGGCCGTGAACTTGATTTTCGTCCACCCTGGCCGCGCATTGCGATGGCAACAGCGATTGCCGAC
CGCACCGGTATCGACATTACCCAGATCACCGATCTGGATGCCTTACAAGAAGCTATCAGCGCACGTGGATTGCGGGTTGA
ACGCAAGGCGTCGTGGGCAAAGCAGGTTGACGAACTCTTCTCGGAGTTTGTACAACCTCATCTGTTCCAGCCAACCTTCA
TCATCGATTATCCGGTGGCGATGTCGCCGCTGGCAAAGCGGATTCCTGACCGGCCTGATTTTACCGAGCGCTTCGAGGCC
TTTATCGCCGGTATGGAGATTGGCAATGCCTTCACCGAGTTGAATGATCCATTCGACCAGGAAGAACGCTTCCGTGAACA
GTTACGCGCCTTCGCTGCCGGTGATGAAGAGGCGCACCAGATGGACGAAGATTTTATCAATGCGCTACGTTACGGTATGC
CACCGACCGGTGGTCTTGGGGTAGGTATCGACCGCCTGGTGATGGTCTTGACCGATCAATCCAACATTCGCGAAGTGATT
CTCTTCCCGCATTTGCGGGAACGGTCTGATGAGTAG

Protein sequence :
MELNDLQAQRAAKLAELRAAGLDPYPPRCYRSHTIAEALAAFDDLVAQSTTLTLTGRIIGARRIMGKIAFAHIEDGTGEI
QLWLSRADLGDEWFERFRDQLDTFDIVQASGVLRCTKTGERSLFVRELAILAKAINPPPEKWAGLQDVEERHRQRYLDLI
VNRDRREIFRARARVISTMRRVLDERGFLEVETPVLQPLYGGAAARPFITYHNALGQNLYLRIATELYLKRLIVGGFPGV
YEIGKNFRNEGVDRSHNPEFTMMECYQAYADYHAMMTLVEEMLSEICLAVHGTTTITYQGRELDFRPPWPRIAMATAIAD
RTGIDITQITDLDALQEAISARGLRVERKASWAKQVDELFSEFVQPHLFQPTFIIDYPVAMSPLAKRIPDRPDFTERFEA
FIAGMEIGNAFTELNDPFDQEERFREQLRAFAAGDEEAHQMDEDFINALRYGMPPTGGLGVGIDRLVMVLTDQSNIREVI
LFPHLRERSDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 7e-96 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001634844.1 lysyl-tRNA synthetase VFG1668 Protein 4e-96 48