Gene Information

Name : Mext_4718 (Mext_4718)
Accession : YP_001642157.1
Strain : Methylobacterium extorquens PA1
Genome accession: NC_010172
Putative virulence/resistance : Virulence
Product : phosphate regulon transcriptional regulatory protein PhoB
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 5270439 - 5271158 bp
Length : 720 bp
Strand : +
Note : TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: xau:Xaut_0202 two component transcriptional regulator, winged helix family

DNA sequence :
ATGGAAAGACGGACGATGACGAGTGCGCACATCCTGATCGTCGAGGACGAGGAATCGCTGACGACCCTGCTGCGCTACAA
TCTCGAAGCGGAGGGTTTCCAAGTCGATGTCGCGGTTCGCGGCGACGAGGCCGACCTTCGCCTGCACGAGACCACGCCCG
ACCTCGTACTCCTCGACTGGATGGTGCCGGGGCTCTCGGGGATCGAGCTGTGCCGGCGCATCCGTGCCCGCCGTGAGACC
GAACGCCTGCCAGTCATCATGCTGACCGCCCGGGGCGAAGAGACCGACCGTGTGCGCGGCCTCTCGACCGGCGCCGACGA
CTACGTCGTCAAGCCGTTCTCCGTGCCGGAGCTGCTCGCCCGTGTCCGTGCGCTCCTGCGCCGCGCCAAGCCCACCCACG
TTTCCGACATGCTCGTGGCGGGCGATATCGAGCTCGACCGCGTCAGCCATCGCATCCGCCGGCAGGGCCGCGAGATCCAT
CTCGGGCCGACCGAGTTCAAGCTGCTCGAATACCTGATGCAGAGCCCCGGCCGGGTCTTCTCGCGGGAGCAGTTGCTCGA
CGGCGTGTGGGGCCACGACGTCTACATCGACGAGCGCACGGTCGATGTTCATGTCGGCCGCCTGCGCAAGGCGATCAACC
GCCCGCGCCAGAGCGACCCGATCCGCACCGTGCGCGGCTCCGGCTACTCGTTCGACGAGATGTTCGCCGGAGCGGAGTGA

Protein sequence :
MERRTMTSAHILIVEDEESLTTLLRYNLEAEGFQVDVAVRGDEADLRLHETTPDLVLLDWMVPGLSGIELCRRIRARRET
ERLPVIMLTARGEETDRVRGLSTGADDYVVKPFSVPELLARVRALLRRAKPTHVSDMLVAGDIELDRVSHRIRRQGREIH
LGPTEFKLLEYLMQSPGRVFSREQLLDGVWGHDVYIDERTVDVHVGRLRKAINRPRQSDPIRTVRGSGYSFDEMFAGAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 5e-27 43
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 4e-27 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB CP001485.1.gene721.p Protein 4e-23 44
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB NC_012469.1.7686381. Protein 6e-29 42
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB HE999704.1.gene1528. Protein 5e-24 42
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB NC_012469.1.7685629. Protein 9e-27 42
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB AE000516.2.gene3505. Protein 3e-33 42
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB HE999704.1.gene2815. Protein 2e-29 41
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB NC_011595.7057856.p0 Protein 8e-28 41
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB NC_010410.6002989.p0 Protein 8e-28 41
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB NC_010400.5986590.p0 Protein 4e-27 41
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB BAC0125 Protein 1e-22 41
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB CP000647.1.gene2531. Protein 4e-24 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB VFG1563 Protein 3e-27 43
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB VFG1702 Protein 2e-27 43
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB VFG1390 Protein 2e-25 42
Mext_4718 YP_001642157.1 phosphate regulon transcriptional regulatory protein PhoB VFG1389 Protein 8e-21 41