Gene Information

Name : Mext_4234 (Mext_4234)
Accession : YP_001641674.1
Strain : Methylobacterium extorquens PA1
Genome accession: NC_010172
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 4712224 - 4713510 bp
Length : 1287 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCACGACATCCGCGCCATCCGCGAGAACCCAGAGGCCTTCGACCGCGATCTGGAGCGGCGTGGCCTCGCGCCCCTCAG
CGCCGAGCTGATCGCCCTCGACGACGCGCGCAAGGGTGCGGTCTCGGCCGCGCAGGCGGCCCAGGAGCGGCGCAACGCGC
TGTCCAAGGAGATCGGCGCCGCCAAGAAGGCCAAGGACGAGGCCCGTGCGACCGAGCTGATGGCCGAGGTCGCCCGGCTG
AAGGAAGAGGCACCGGGCCTCGAAGCCGCGCAGGGGGAGGCCGCCAAGGCTCTCGACGAGCGTCTCGCCGCGATCCCGAA
CCGTCCGAAGGACGACGTGCCTCCCGGCGCCGACGAGCACGGCAATGTCGAGTACCGCCGCTTCGATTCCTCCCGTGAGC
GCCTGGCGCAAGGGCGCCAGCATTTCGAGCTCGGCGAGGCCACCGGGCTGATGGATTTCGAGGCGGCCGCGAAACTCTCC
GGCTCTCGCTTCGTCGTGCTGAAGGGCCAGCTCGCCCGGCTGGAGCGGGCGCTCGGCCAGTTCATGCTTGACCTGCACAC
GGGCGAGCACGGCTATACCGAGGTGGTGCCGCCGGTCCTCGTGCGTGAGGAAGCGATGTTCGGCACGGCGCAATTGCCGA
AGTTCCGCGATGATCAGTTCGCGGCGGGCGAGAACTTCTGGCTGATCCCCACGGCGGAAGTTCCGCTCACCAACCTCGTG
CGCGAGAGCATCCTGGCGGAGGACGAGCTTCCCTTGCGCTTCACCGCGCTCACCCCCTGCTTCCGCGCCGAGGCCGGAGC
GGCCGGGCGCGACACCCGCGGCATGCTGCGCCAGCACCAGTTCAACAAGGTCGAGCTGGTCTCGATCACCGCACCCGAAA
AGTCGGCCGAGGAGCACGAGCGGATGCTCGCCTGCGCCGAGGCCGTGCTGCAGAAGCTCGATCTCACCTATCGCGTCATG
ACGCTGTGTACCGGTGACATGGGCTTTGCTTCCCAGAAAACCTACGACATCGAGGTCTGGGTGCCGGGCCAGCAGACATA
TCGCGAGATTTCGTCCTGCTCGGTCTGCGGCGAGTTCCAGGCGCGGCGGATGAATGCGCGCTACCGAGCCAAGGAGGGCA
GGGGGGTCGGCTTCGTCCACACCCTGAACGGCTCCGGCGTCGCGGTCGGCCGCGCGCTGATCGCCGTGATGGAGAACTAC
CAGAACCCCGACGGCAGCGTCACGATCCCGTCGGCGCTCCAGCCCTACATGGGCGGCCTCACCCGGATCGAGGGACCGAA
GAACTGA

Protein sequence :
MHDIRAIRENPEAFDRDLERRGLAPLSAELIALDDARKGAVSAAQAAQERRNALSKEIGAAKKAKDEARATELMAEVARL
KEEAPGLEAAQGEAAKALDERLAAIPNRPKDDVPPGADEHGNVEYRRFDSSRERLAQGRQHFELGEATGLMDFEAAAKLS
GSRFVVLKGQLARLERALGQFMLDLHTGEHGYTEVVPPVLVREEAMFGTAQLPKFRDDQFAAGENFWLIPTAEVPLTNLV
RESILAEDELPLRFTALTPCFRAEAGAAGRDTRGMLRQHQFNKVELVSITAPEKSAEEHERMLACAEAVLQKLDLTYRVM
TLCTGDMGFASQKTYDIEVWVPGQQTYREISSCSVCGEFQARRMNARYRAKEGRGVGFVHTLNGSGVAVGRALIAVMENY
QNPDGSVTIPSALQPYMGGLTRIEGPKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-98 51