Gene Information

Name : Mext_3863 (Mext_3863)
Accession : YP_001641306.1
Strain : Methylobacterium extorquens PA1
Genome accession: NC_010172
Putative virulence/resistance : Resistance
Product : arsenical resistance protein ArsH
Function : -
COG functional category : R : General function prediction only
COG ID : COG0431
EC number : -
Position : 4290776 - 4291543 bp
Length : 768 bp
Strand : -
Note : TIGRFAM: arsenical resistance protein ArsH; PFAM: NADPH-dependent FMN reductase; KEGG: har:HEAR1959 NADPH-dependent FMN reductase

DNA sequence : 
GTGGACAAGCCCCATCAGCCGTTCGCCGACGGGTTGCCGAACCTCTCCGAGGCGCATGCCGAACTGCCCCCCGCTGAGCG
GGTGCAGGCGTCGACGCCGCTCGCGCACGCGCCGCGCTTCCTGATCCTCTACGGTTCGCTCCGGGAGCGCTCCTTCAGCC
GGTTCCTGGCCTACGAGGCGGCCCGGTTGCTGGAGGCGATGGGCGGAGAGTTGCGGATCTTCCATGCGCACGGCCTGCCG
CTCCCCGACAACACAACCGCCGACCACCCGAAGGTGCGGGAGCTCCGCGAACTCTCGGTCTGGTCCGAGGGGCAGGTCTG
GGTGAGCCCCGAGCGGCACGGCAACCTGACCGGGGTGATGAAAAGCCAGATCGATTGGCTGCCGCTGAGCGAGGGCTCGG
TCCGCCCGACGCAGGGGCGCACGCTCGCGGTGATGCAGGTGTCGGGCGGTTCGCAGAGCTTCAATGCGGTGAACAGCCTG
CGGGTGCTCGGGCGCTGGATGCGGATGATCACCATCCCGAACCAGTCCTCGGTACCGATGGCCTACAAGGAGTTCGACGA
GGCCGGCCGCATGAGGCCGGGACCGCTCTATGACCGGGTCGTGGACGTGTGCGAGGAGCTGATGAAGTTCACGCTCCTGA
CCCGCGGACGGGCCGATTACCTCGTCGATCGCTACTCCGAGCGCAAGGAGCGTGACCCCGACCGGCTCAAGGCGGTCGCC
GCCGATGTGGGCTTTGTCCGGGCGCCATCCGCCGAGCGGGCATCGTAG

Protein sequence : 
MDKPHQPFADGLPNLSEAHAELPPAERVQASTPLAHAPRFLILYGSLRERSFSRFLAYEAARLLEAMGGELRIFHAHGLP
LPDNTTADHPKVRELRELSVWSEGQVWVSPERHGNLTGVMKSQIDWLPLSEGSVRPTQGRTLAVMQVSGGSQSFNAVNSL
RVLGRWMRMITIPNQSSVPMAYKEFDEAGRMRPGPLYDRVVDVCEELMKFTLLTRGRADYLVDRYSERKERDPDRLKAVA
ADVGFVRAPSAERAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsH YP_001007636.1 putative arsenic resistance protein Not tested YAPI Protein 6e-71 74
BCAM0236 YP_002232867.1 putative NADPH-dependent FMN reductase Not tested BcenGI11 Protein 1e-75 70
arsH AFC76432.1 ArsH Not tested AbaR5 Protein 7e-70 61
arsH CAJ77015.1 arsenic resistance protein Not tested AbaR1 Protein 6e-70 61
arsH ADZ05766.1 arsenic resistance protein Not tested AbaR11 Protein 6e-70 61

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mext_3863 YP_001641306.1 arsenical resistance protein ArsH BAC0595 Protein 1e-62 67
Mext_3863 YP_001641306.1 arsenical resistance protein ArsH BAC0034 Protein 2e-69 64