Gene Information

Name : guaA (Mext_2931)
Accession : YP_001640391.1
Strain : Methylobacterium extorquens PA1
Genome accession: NC_010172
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3273933 - 3275498 bp
Length : 1566 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCATCGATACCTCCCACCACGACAAGATCCTGATCGTCGATTTCGGCTCCCAGGTGACGCAGCTCATCGCCCGCCG
CGTGCGCGAGGAGGGCGTCTATTGCGAGATCGTGCCGTTCACGAAGGCCGACGCCGCCTTCGAGGCGCACCGGCCCAAGG
GCGTGATCCTGTCGGGGGGGCCAGAATCGGTCACGACTGATCTCTCGCCGCGCGCCCCGCAAAAAATCTTCGAATCCGGC
GTGCCGGTCTTCGGCATCTGCTACGGCCAGCAGACCATGGCGGCCCAGCTCGGTGGCGAGGTCGAGGGTGGCCACCATGC
CGAGTTCGGCCGCGCCGAGGTCGAGATCGTCTCGGACTCGCCGCTGTTCCGGGGGGTCTGGCACGCGGGTGAGAAATACC
CGGTCTGGATGAGCCACGGCGACCGGGTGACCAAGCTGCCGGATGGCTTTGCCACCATCGCGATGTCGCGCAACGCGCCC
TTCGCCGCGGTGGCGGACGAGGCCCGCCATTACTACGCCGTCCAGTTCCATCCGGAGGTGCACCACACCCCGCATGGCGC
GCTGCTGATCCGCAACTTCGTGCGCGACATCGCCGGCTGCTCCGGCGACTGGACCATGGGCACCTACCGCGAGGAGGCGA
TCGCCAAGATCCGCGAGCAGGTCGGCAAGGAAAAGGTGATCTGCGGCCTCTCCGGCGGCGTCGACTCCTCGGTCGCGGCG
GTGCTGATCCACGAGGCGATCGGCGATCAACTCACCTGCGTCTTCGTCGATCACGGCCTGATGCGCCTCGGCGAGGGCGA
CGAGGTCGTCCGCCTGTTCCGCGACCACTACAACATCCCCCTCGTCCACGTTCAGGCGCAGGATCTGTTCATCGGCGCGC
TCGAGGGCGTCGATGACCCCGAGGTGAAGCGCAAGACGATCGGCCGGCTGTTCATCGACGTGTTCGAGGCCGAGGCCGGC
AAGATCGGCGGCGCCGCCTTCCTCGCCCAGGGCACGCTCTACCCGGACGTGATCGAGAGCGTGTCGTTCTCCGGCGGTCC
CTCCGTGACGATCAAGAGCCACCACAATGTCGGCGGCCTGCCCGAGCGGATGAACATGAAGCTCGTGGAGCCCCTGCGCG
AGCTGTTCAAGGACGAGGTTCGCCTGCTCGGCAAGGAACTCGGCCTGCCCGAGAGCTTCGTCGGCCGCCACCCCTTCCCC
GGACCGGGCCTCGCCATTCGCTGCCCTGGGATGATCACGCGCGAGAAGCTGGAGGCCCTGCGCAAGGCCGACGCGATCTA
TCTCGACGAGATCCGGCAGGCCGGCCTCTACGACACGATCTGGCAGGCCTTCGCGGTGATCCTGCCGGTGAAGACGGTGG
GCGTGATGGGCGACGGGCGCACCTACGACCATGTCTGCGCCCTGCGCGCCGTCACCTCGGTCGATGGCATGACTGCCGAC
TTCTACCCCTTCGACATGGCCTTCCTCGGCCGCGTCGCGACGCGGATCATCAACGAGGTGAAGGGCATCAACCGAGTGAC
CTACGACATCACCTCGAAGCCGCCGGGCACGATCGAGTGGGAGTAA

Protein sequence :
MTIDTSHHDKILIVDFGSQVTQLIARRVREEGVYCEIVPFTKADAAFEAHRPKGVILSGGPESVTTDLSPRAPQKIFESG
VPVFGICYGQQTMAAQLGGEVEGGHHAEFGRAEVEIVSDSPLFRGVWHAGEKYPVWMSHGDRVTKLPDGFATIAMSRNAP
FAAVADEARHYYAVQFHPEVHHTPHGALLIRNFVRDIAGCSGDWTMGTYREEAIAKIREQVGKEKVICGLSGGVDSSVAA
VLIHEAIGDQLTCVFVDHGLMRLGEGDEVVRLFRDHYNIPLVHVQAQDLFIGALEGVDDPEVKRKTIGRLFIDVFEAEAG
KIGGAAFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRLLGKELGLPESFVGRHPFP
GPGLAIRCPGMITREKLEALRKADAIYLDEIRQAGLYDTIWQAFAVILPVKTVGVMGDGRTYDHVCALRAVTSVDGMTAD
FYPFDMAFLGRVATRIINEVKGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-129 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-129 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-129 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-115 51