Gene Information

Name : Mext_1610 (Mext_1610)
Accession : YP_001639080.1
Strain : Methylobacterium extorquens PA1
Genome accession: NC_010172
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1798088 - 1799980 bp
Length : 1893 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCACCCGTCCGTCCCAAAGATCTTCCCAACAGCAATCCCGCCAGCGTGACCACCGGCCCCGTGCAGGGCTCGCG
CAAGGTCTATGCGGAGGCGCCCGGCCGCCCCGACATTCGCGTGCCCTACCGGGAGATCGCCCTCTCCGACCCGAAGGAGG
AGCCGGTGCGGGTCTACGACCCGTCGGGCCCCTACACCGAGACCGATGCGGCCATCGACCTCGAGAAGGGTCTGGCCCCG
GTCCGCGAGCCGTGGATCGTCGGGCGCGGCTACGCCGCCGTGAAGCCGCGCGAGGTGAAGCCGGAGGACAACGGATTCGC
GGCTGCCGACAAGCTCGTGGCGCCATGCCCCGCCGAGCGGACGATCCGCCGGGCCGAGCCGGGGCAGTTGGTGACGCAGT
ACGAATTCGCCCGCGCCGGGATCATCACGGAAGAGATGATCTATGTGGCGCATCGCGAGAACGCCTGCCGCGCGCAGATG
CTGGAGCGGGCGCAAGCCGCGCTCGCCGACGGCGACAGTTTCGGCGCAGCGGTGCCGCCCTTTATCACGCCCGAATTCGT
CCGCGACGAGGTGGCCCGCGGGCGTGCCATCATCCCGGCCAACATCAACCACCTCGAACTCGAGCCGATGGCGATCGGCC
GCAATTTTTTGGTGAAAATCAACGCCAATATCGGCAACTCGGCGGTGACGTCTTCCGCGGCTGAGGAAGTCGAAAAACTG
GTCTGGTCGATCCGCTGGGGTGCGGACACGGTCATGGACCTCTCGACGGGCCGCAACATCCACAACATCCGCTCGTGGAT
CGTGCGCAACTCGCCCGTCCCGATCGGCACCGTGCCGATCTATCAGGCGCTGGAAAAGGTCGGCGGCGACCCGCTGAAGC
TCGATTGGGAGGTGTTCAAGGACACGCTCATCGAACAGGCCGAGCAGGGCATCGACTACTTCACGATCCATGCCGGCGTG
CGGCTGGCCCATGTGCCGCTGACCGCGCGGCGCACCACCGGCATCGTGTCGCGCGGCGGCTCGATCATGGCGCGCTGGTG
CCTCGCCGGGCACCGCGAATCGTTCCTCTACGAGCGGTTCGACGAGATCTGCGACATCATGCGGGCCTACGACGTGTCGT
TCTCGCTCGGCGACGGCCTGCGTCCCGGCTCGATTGCGGATGCCAACGACGCGGCCCAGTTCGCCGAACTGGAGACCCTG
GGCGAACTCACCAAGATCGCCTGGGACAAGGGCTGCCAGACCATGATCGAGGGCCCCGGCCACGTGCCGATGCACAAGAT
CAAGGTCAACATGGAGAAGCAGCTGCGCGAGTGCGGCGAGGCGCCGTTCTACACCCTCGGCCCGCTGACCACCGACATCG
CGCCGGGCTACGACCATATCACCTCGGGCATCGGCGCGGCGATGATCGGCTGGTTCGGCACGGCGATGCTCTGCTACGTC
ACGCCGAAGGAGCATCTCGGGCTGCCGAACCGCGACGACGTGAAGACCGGCGTCATCACCTACAAGATCGCCGCGCACGC
CGCCGACCTCGCCAAGGGCCACCCCGCCGCGCAGCTCCGCGACGACGCCCTCAGCCGCGCCCGGTTCGACTTCCGCTGGG
AGGACCAGTTCAACCTCTCGCTGGATCCCGACACGGCGCGCGCCTACCACGACGAGACCCTGCCGAAGGACGCGCACAAG
GTCGCCCATTTCTGCTCGATGTGCGGCCCGAAATTCTGCTCGATGAAGATCACGCAGGATCTGCGCGCCGACGTGCTCGC
CATGGAAGAGGCCGGCATCGTCATCGGCCAAGCCCAGCCGATGAGCGACGCCGAGCGCCAGGCCGGCATGGCGGCCAAGT
CGCAGGAGTTCCTGGAAGAGGGCGGCAAGCTCTACGTCGACGCGGCGGAGTAA

Protein sequence :
MNAPVRPKDLPNSNPASVTTGPVQGSRKVYAEAPGRPDIRVPYREIALSDPKEEPVRVYDPSGPYTETDAAIDLEKGLAP
VREPWIVGRGYAAVKPREVKPEDNGFAAADKLVAPCPAERTIRRAEPGQLVTQYEFARAGIITEEMIYVAHRENACRAQM
LERAQAALADGDSFGAAVPPFITPEFVRDEVARGRAIIPANINHLELEPMAIGRNFLVKINANIGNSAVTSSAAEEVEKL
VWSIRWGADTVMDLSTGRNIHNIRSWIVRNSPVPIGTVPIYQALEKVGGDPLKLDWEVFKDTLIEQAEQGIDYFTIHAGV
RLAHVPLTARRTTGIVSRGGSIMARWCLAGHRESFLYERFDEICDIMRAYDVSFSLGDGLRPGSIADANDAAQFAELETL
GELTKIAWDKGCQTMIEGPGHVPMHKIKVNMEKQLRECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYV
TPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFDFRWEDQFNLSLDPDTARAYHDETLPKDAHK
VAHFCSMCGPKFCSMKITQDLRADVLAMEEAGIVIGQAQPMSDAERQAGMAAKSQEFLEEGGKLYVDAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 64
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 3e-178 61