Gene Information

Name : lysS (Bpet2768)
Accession : YP_001631378.1
Strain : Bordetella petrii DSM 12804
Genome accession: NC_010170
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 2911167 - 2912687 bp
Length : 1521 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACCGACCATTCGCCCGCCCCGGCCGCCCAGGATGAAAACCGCTTGATCGCCGAACGGCGCGCCAAGCTGTCCAAGCT
GCGCGAAGCCGGCGTTGCGTATCCCAACGATTTCGTGCCGGATGCGCACGCCGCCGACCTGCACCGCCAGTACGGCGAAC
AAGACCAGGAAGCGCTGGCCGCCGCCGGCGTGCAGGTGAAGGTCGCGGGCCGCATGATGCTCAAGCGCGTGATGGGCAAG
GCCAGTTTCGCCACCGTGCAAGACGGCAGTGGCCGCATCCAGATCTACCTCGATCGCGGCACCCTCGGCGACGAAGCCTA
TGCCGCTTTCAAGCAATGGGACATCGGCGACATCATCGCGATCGAAGGGTCGGTATTCAAAACCAACAAGGGCGAGCTCT
CGGTGCATGCCGCCACGGCGCGCCTGCTGTCGAAATCGCTGCGCCCCCTGCCCGACAAGTTCCACGGCGTGGCCGACCAG
GAACTGCGGTACCGCCAGCGCTACGTCGACCTCATCATGACCGATGCCACGCGGCGCACGTTCGAGACGCGCAGCAAGGC
CGTGGGCAGCATCCGCCAGGTCATGCTCGACGCCGGCTTCCTGGAAGTCGAGACGCCCATGCTGCACCCCATTCCGGGCG
GCGCGGCGGCCAAGCCCTTCGTCACGCACCACAATGCGCTCGACATGGAAATGTTCCTGCGCATCGCTCCCGAGCTTTAT
CTGAAGCGGCTGATCGTGGGCGGATTCGAGCGTGTTTTCGAGATCAACCGAAATTTCCGCAACGAAGGCGTGAGCCCCCG
GCACAATCCCGAATTCACCATGATGGAGTTCTACGCGGCCTATGCGGATTACCGCTGGCTGATGGACTTCACCGAACACG
TCCTGCGCCAGGCGGCCATTGCGGCCACCGGCAGCGCGGTGCTCACCTATCAAGACCGCGAGCTCGACCTGTCCCGGCCG
TTCGACCGCCTGACCATCTGCGAAGCCATCCTGAAGTACGCTCCCGCCTACACCCAGGCCCAACTCGATGACGCCGCCTT
CGTGCGCGCCGAACTAAAAAAACTGGGCGCCGACGTCGACGGCCCAGTGCTGGCGCGCGCCGGACTGGGAGCCCTGCAGC
TGGCGCTCTTCGAAGAAACCGCCGAAGCGCAACTCTGGAACCCGACCTACATCATCGACTACCCGGTCGAGGTATCGCCG
CTGGCCCGCGCCTCCGATACGCGCCCCGGCATCACCGAGCGCTTCGAACTCTTCATGACCGGCCGTGAAATCGCCAACGG
CTTCTCCGAACTGAACGACCCCGAAGACCAGGCCGAACGCTTCCGCGCCCAGGTCGAAGCCAAGGACGCCGGCGACGAAG
AAGCCATGTACTTCGACGCCGACTACATCCGCGCGCTCGAATACGGCATGCCGCCCACCGGCGGTTGCGGCATCGGCATC
GACCGCCTGGTCATGCTGCTGACCAACAGCCCCAGCATCCGCGACGTCATCCTGTTCCCGCACCTGCGGCGCGAAGACTG
A

Protein sequence :
MTDHSPAPAAQDENRLIAERRAKLSKLREAGVAYPNDFVPDAHAADLHRQYGEQDQEALAAAGVQVKVAGRMMLKRVMGK
ASFATVQDGSGRIQIYLDRGTLGDEAYAAFKQWDIGDIIAIEGSVFKTNKGELSVHAATARLLSKSLRPLPDKFHGVADQ
ELRYRQRYVDLIMTDATRRTFETRSKAVGSIRQVMLDAGFLEVETPMLHPIPGGAAAKPFVTHHNALDMEMFLRIAPELY
LKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYADYRWLMDFTEHVLRQAAIAATGSAVLTYQDRELDLSRP
FDRLTICEAILKYAPAYTQAQLDDAAFVRAELKKLGADVDGPVLARAGLGALQLALFEETAEAQLWNPTYIIDYPVEVSP
LARASDTRPGITERFELFMTGREIANGFSELNDPEDQAERFRAQVEAKDAGDEEAMYFDADYIRALEYGMPPTGGCGIGI
DRLVMLLTNSPSIRDVILFPHLRRED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-134 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001631378.1 lysyl-tRNA synthetase VFG1668 Protein 6e-135 56