Gene Information

Name : guaA (Bpet2085)
Accession : YP_001630694.1
Strain : Bordetella petrii DSM 12804
Genome accession: NC_010170
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2174700 - 2176295 bp
Length : 1596 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCACCACCAGCGCATTCTCATTCTTGACTACGGTTCGCAAGTTACCCAACTGATCGCCCGCCGCGTGCGCGAAGCCGG
CGTGTATTCCGAGATCCATCCCGGCGACGTCGATGATGCCTTCGTGCGCGACCAGGCAGGGCAGGGGCTCAAGGGCATCA
TTCTGTCGGGCAGCCATGCGTCGGCCTATGCGGAAGATTCGCTGCGCGTGCCGGCCGCCGTGTTCGAACTGGGCGTGCCG
GTGCTGGGCATTTGCTACGGCATGCAGTCGATGGCTCAGCAACTGGGCGGCACGGTAAGCTTTTCCGATCATCGCGAATT
CGGCTATGCCGAGGTGCGCGCCCATGGCCATACCCGGCTGCTGGACGGCCTGGCCGACTTCACCACGCCCGAAGGCCACG
GCATGCTGAAGGTGTGGATGAGCCACGGCGACAAGGTCACCGCGCTGCCGCCCGGCTTCAAGGTCATGGCCTCGACCCCG
TCGTGCCCCATCGCCGGCATGGCCGACGAAACCCGCAATTTCTACGCGGTGCAATTCCACCCCGAAGTCACGCACACCGT
GCAGGGCAAAGCCATGCTGGCCCGCTTCGTCAACGAGATCTGCGGCTGCCAGGGCGACTGGAACATGCCCGACTACGTGT
CTGAAGCCGTGGCGCGCATTCGCGAACAGGTCGGCAGCGACGAAGTCATCCTGGGCCTGTCGGGCGGCGTGGACTCGTCC
GTGGCCGCGGCCCTGATCCACAAGGCCATAGGCGACCAGCTGACCTGCGTGTTCGTCGACCATGGCCTGCTGCGCCTGGA
CGAAGGCAAGCAGGTAATGCAGACGTTCGCCGAGAACATGGGCGTGAAGATCATCCATGTCGACGCCACCGAACAGTTCA
TGGGCAAGCTGGCCGGCCAGGCCGACCCCGAAGCCAAGCGCAAGATCATCGGCCGCGAGTTCGTCGAGGTATTCCAGGCC
GAAGCCGGCAAGCTGAAAAGCGCCAAGTGGCTGGCCCAGGGCACCATCTACCCCGATGTCATCGAATCGGCCGGCGCCAA
GACCGGCAAGGCCACGTCGATCAAGTCGCACCATAACGTGGGCGGCCTGCCCGACACGCTGAACCTGCAACTGCTGGAAC
CCCTGCGCGAACTGTTCAAGGACGAAGTGCGCGAGCTGGGTGTGGCCCTGGGCCTGCCGCCGCAGATGGTGTATCGCCAT
CCGTTCCCCGGCCCCGGCCTGGGTGTGCGCATCCTGGGCGAGGTCAAGCAGGAATTCGCCGACCTGCTGCGCCGCGCCGA
TGCCATTTTCATCGACGAACTGCGCAGCACCATCGACGAAACCAGCGGCAAGAGCTGGTACGACCTGACCTCGCAGGCCT
TCGCCGTGTTCCTGCCGGTAAAGTCAGTTGGCGTGATGGGCGATGGCCGCACGTATGAATACGTGGTGGCCCTGCGCGCG
GTGCAGACCTTCGATTTCATGACCGCCGACTGGGCGCCGCTGCCGCATGCGCTGCTGGCCCGCGTATCGTCGCGCATCAT
CAACGAAGTGCGTGGCATCAATCGCGTGGTGTACGACGTGTCGAGCAAGCCGCCGGCGACGATTGAGTGGGAGTGA

Protein sequence :
MHHQRILILDYGSQVTQLIARRVREAGVYSEIHPGDVDDAFVRDQAGQGLKGIILSGSHASAYAEDSLRVPAAVFELGVP
VLGICYGMQSMAQQLGGTVSFSDHREFGYAEVRAHGHTRLLDGLADFTTPEGHGMLKVWMSHGDKVTALPPGFKVMASTP
SCPIAGMADETRNFYAVQFHPEVTHTVQGKAMLARFVNEICGCQGDWNMPDYVSEAVARIREQVGSDEVILGLSGGVDSS
VAAALIHKAIGDQLTCVFVDHGLLRLDEGKQVMQTFAENMGVKIIHVDATEQFMGKLAGQADPEAKRKIIGREFVEVFQA
EAGKLKSAKWLAQGTIYPDVIESAGAKTGKATSIKSHHNVGGLPDTLNLQLLEPLRELFKDEVRELGVALGLPPQMVYRH
PFPGPGLGVRILGEVKQEFADLLRRADAIFIDELRSTIDETSGKSWYDLTSQAFAVFLPVKSVGVMGDGRTYEYVVALRA
VQTFDFMTADWAPLPHALLARVSSRIINEVRGINRVVYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-124 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-124 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-124 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-107 49