Gene Information

Name : topB3 (Bpet1448)
Accession : YP_001630053.1
Strain : Bordetella petrii DSM 12804
Genome accession: NC_010170
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1502488 - 1504500 bp
Length : 2013 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGGCTGTTCTTGTGCGAGAAGCCCTCCCAGGGCAAAGACATTGGCCGGATTCTCGGCGCCACGCAGCGCGGTGAAGG
CTGTCTCAACGGTTCCGGCGTCACTGTCACCTGGTGCATCGGCCATCTCGTAGAAGCCGCTGCGCCCGAAGCCTACGACG
AGCAGTTGAAGCGCTGGTCCATTGAGCAGTTGCCCATCATTCCCCAGAATTGGCGGGTCGAGGTCAAACCGAAGACCGCC
ACGCAATTCAAGGTCGTCAAGGCGCTTCTGGCGAAGGCGACCCAGCTTGTCATCGCCACCGATGCCGACCGCGAAGGCGA
GTTGATCGCTCGCGAGATCATCGAACTGTGCGGCTACCGCGGCCCCATCGAGCGGCTATGGTTGTCGGCACTCAACGATG
CGTCCATCCGCGCCGCACTGGGCAAGCTCAGGCCATCGGCCGAGACGCTGCCGATGTACTACTCGGCGCTGGCACGATCG
CGGGCCGACTGGCTCGTGGGAATGAACCTCAGCCGCCTGTTCACCGTGCTCGGTCGACAAGCGGGCTACGACGGCGTGCT
GTCGGTCGGCCGCGTGCAGACACCGACGCTCAAGCTCGTGGTGGACCGCGACCGCGAAATTGCGGCCTTCGTGTCCGTAC
CGTACTGGGCCATCGACGTGTCCCTGTCCGCAAGCGGCCAGTCTTTCACCGCGCAATGGGTTCCGCCCGATGCCTACACC
GACGACACGGGCCGCTGCCTGCAGCAGCCGGTCGCACAGCGGGCCGCGCAGCAGATTCGCGGCGCGGGCAGCGCGCAGGT
GGTGTCGGTCGAGACCGAGCGCGTGCGCGAAGGCCCGCCGCTGCTGTTCGACCTGGGCACCTTGCAGGAGGTTTGTTCCA
AGCAACTTGGGCTGGACGTGCAGGAAACCCTGGAGATCGCCCAGGCCCTGTACGAGACGCACAAAGCCACGACGTACCCG
CGCTCGGATTCCGGCTATCTGCCCGAAAGCATGTTCGCCGAGGTGTCCACGGTTCTCGACAGTCTGCTCAGGACCGATCC
CTCGCTGCGCCCGATCATGGACCAGCTCGACCGCTCCCAGCGCTCGCGTGCATGGAATGACGGCAAGGTCACGGCGCACC
ACGGCATCATTCCGACGCTCGAACCAGCGAACCTCTCGGCCATGAGCGAGAAGGAGTTGGCGGTGTACCGGCTGATCCGG
GCGCATTACCTCGCGCAGTTCCTCCCTCACCACGAGTTCGATCGCACCGTGGCGAACCTAGCCTGCGGCCAGCAGAAACT
GGCGGCCACGGGCAAGCAGGTCGTGGTGAAGGGCTGGCCCCTGGTACTGACCGAGCCTCAGCCCGACGAGGACGGCGACG
CTGCGGCGCGCAGCCAGGTGCTTCCCGCGCTGCGCGAGGGCTTGGCATGTCTGGTGGCCGACGTCGATCTGAAGGCGCTC
AAGACGCTGCCACCCAGGCCGTACACGCAGGGCGAACTTGTCAAATCCATGAAGGGAGTCGCCAAGCTGGTGACGGACCC
GCGCCTGAAGCAGAAGTTCAGGGACACGGTCGGCATCGGCACCGAAGCGACGCGAGCCAACATCATCAGCGGCCTGATCG
CACGCGGCTATATCGTGAAGAAGGGGCGCGCCATCCGCGCATCCGATGCTGCTTTCACACTGATCGACGCCGTGCCCGCG
GCGATCGCCGACCCTGGCACTACCGCTGTCTGGGAACAGGCGCTCGACATGATCGAAGCTGGACAGCTTACGCTGGACGT
ATTCATCGGAAAGCAGGCTGCATGGATTTCGCAGTTGATCGCGCAGTACAGCATCGCGTCCCTGTCCATCAAGGTTCCCC
AAGGGCCGGCATGCCCGCAGTGCGGCGCACCCACGCGTCAGCGCAGCGGCAAGAGCGGCCCGTTTTGGTCGTGCAGTCGT
TACCCCGACTGCAAAGGCACGCTGCCGGTCGAATCCGGCACGTCCAAGCGCGGTGCCTCGCGCCCGCACCGCAGCGGCCG
CCAAGGTTCCTGA

Protein sequence :
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEAYDEQLKRWSIEQLPIIPQNWRVEVKPKTA
TQFKVVKALLAKATQLVIATDADREGELIAREIIELCGYRGPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARS
RADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSASGQSFTAQWVPPDAYT
DDTGRCLQQPVAQRAAQQIRGAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYP
RSDSGYLPESMFAEVSTVLDSLLRTDPSLRPIMDQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIR
AHYLAQFLPHHEFDRTVANLACGQQKLAATGKQVVVKGWPLVLTEPQPDEDGDAAARSQVLPALREGLACLVADVDLKAL
KTLPPRPYTQGELVKSMKGVAKLVTDPRLKQKFRDTVGIGTEATRANIISGLIARGYIVKKGRAIRASDAAFTLIDAVPA
AIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYSIASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSR
YPDCKGTLPVESGTSKRGASRPHRSGRQGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 91
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 75
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 63
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 7e-167 49
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 7e-167 49
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 5e-167 49
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 1e-167 49
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 3e-167 49
topB AAW83109.1 TopB Not tested GGI Protein 5e-121 41