Gene Information

Name : topB2 (Bpet1037)
Accession : YP_001629640.1
Strain : Bordetella petrii DSM 12804
Genome accession: NC_010170
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1104554 - 1106575 bp
Length : 2022 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGGCTGTTTCTGTGCGAGAAGCCCTCCCAGGGCAAAGACATCGGCCGGATTCTCGGCGCCACGCAGCGCGGTGAAGG
CTGCCTCAACGGCTCCGGCGTCACGGTCACCTGGTGCATCGGCCATCTCGTCGAAGCGGCAGCACCCGAGGTCTATGACG
CGGCGCTCAAGCGCTGGTCGTTGGAGCAGTTGCCCATCATCCCTCAGCAGTGGCGGGTCGAGGTCAAACCGCAGACCGCC
ACGCAATTCAAGGTCGTCAAAACGCTTCTGGCGAAGGCGACCCATCTCGTCATTGCCACCGATGCCGACCGCGAGGGTGA
ACTGATCGCCCGCGAGATCATCGACCTGTGCGGATACCGCGGCCCCATCGAACGCCTGTGGCTGTCGGCGCTCAACGATG
CGTCCATCCGCACCGCGCTCGCCAAGCTGCGGCCCTCGGCCGAGACGCTGCCGATGTATTACTCGGCGCTGGCGCGCTCG
CGCGCCGACTGGCTTGTGGGCATGAACCTCAGCCGGCTGTTCACCGTGCTCGGGCGGCAGGCCGGCTACGACGGCGTGCT
GTCGGTCGGGCGTGTACAGACCCCGACGCTCAAACTCGTGGTGGACCGCGACCGAGAGATCGCGGCCTTCGAGTCCGTGC
CCTACTGGGCCATCGACGTGTCCCTGTCCGCAGGCGGTCAGACGTTCACCGCGCAGTGGGTGGCACCCGATGCCAGCACC
GACGACGCCGGCCGCTGCCTGCAGCAGCCCGTCGCACAGCAAGCCGCGCAGCAGATCCGCGCCGCGGGCAGTGCCCAGGT
GGTGTCGGTCGAGACCGAGCGCGTGCGCGAAGGCCCGCCGCTGCTGTTCGACCTGGGCACCCTGCAGGAGGTGTGCTCCA
AGCAGCTTGGGCTGGACGTGCAGGAGACGCTGGAGATCGCTCAGGCCCTGTACGAGACGCACAAGGCCACGACGTACCCG
CGCTCGGATTCCGGCTACCTGCCCGAAAGCATGTTCGCCGAGGTGCCTACGGTCCTCGACAGCCTGCTCAAGACCGATCC
CTCGCTGCGCCCGATCATGGAGCAGCTCGACCGCTCCGTGCGTTCGCGCGCCTGGAACGACACGAAGGTGTCCGCGCACC
ACGGCATCATCCCGACACTCGAACCGGCAAACCTCTCCGCCATGAGCGAGAAGGAACAGGCGGTGTACCGGCTGATCCGG
GCGCATTACCTGGCCCAGTTCCTCCCTCATCACGAGTTCGACCGTACCGTGGCCGAGCTTTTCTGCGGCCAGCAGAAGCT
GGTGGCCACGGGCAAGCAAGTCGTCGCCAAGGGCTGGCGCCTGGTGCTGGCCGAACCGCAAGCGGACGAGGACGGCGATG
GTGCCGCGCGCAGCCAGGTGCTGCCTGCGCTGCGTGACGGGATGGCATGCCAGATCGCCGGGGCCGACATCAAGGCCCTC
AAGACGATGCCGCCTAAGCCCTATACCCAGGGCGAACTGGTCAAGGCGATGAAGGGCGTTGCGCGTTTCGTGACCGACCC
GCGCCTGAAGCAGAAGCTCAAGGACACGACGGGCATCGGCACCGAGGCGACGCGGGCCAACATCATCAGCGGGCTGATCG
CCCGCGGCTACATCGTGAAGAAGGGACGCTCCATCCGCGCATCGGATGCGGCGTTCACGCTGATCGACGCCGTGCCCGCG
GCGATTGCCGACCCCGGCACCACCGCCGTCTGGGAACAGGCGCTGGACATGATCGAGGGCGGACAACTCACCCTGGATGT
GTTCATCGGCAAGCAGGCCGCCTGGATTTCGCAGTTGATCGCGCAGTACGGCAGCACGTCCCTGTCCATCAAGGTTCCCC
AAGGACCGGCTTGTCCGCAGTGCGGCGCACCCACGCGCCAGCGCACCGGCAAGAGCGGCCCGTTCTGGTCGTGCAGTCGC
TACCCCGACTGCAAAGGCACGCTGCCGGTGGCAACCGGCACGTCCAGGCGTGGTGCCTCGCGTCCACGCCGTACCAGTGG
CGGCGGCCGCAAAGGCTCCTGA

Protein sequence :
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPQTA
TQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALAKLRPSAETLPMYYSALARS
RADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFESVPYWAIDVSLSAGGQTFTAQWVAPDAST
DDAGRCLQQPVAQQAAQQIRAAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYP
RSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMEQLDRSVRSRAWNDTKVSAHHGIIPTLEPANLSAMSEKEQAVYRLIR
AHYLAQFLPHHEFDRTVAELFCGQQKLVATGKQVVAKGWRLVLAEPQADEDGDGAARSQVLPALRDGMACQIAGADIKAL
KTMPPKPYTQGELVKAMKGVARFVTDPRLKQKLKDTTGIGTEATRANIISGLIARGYIVKKGRSIRASDAAFTLIDAVPA
AIADPGTTAVWEQALDMIEGGQLTLDVFIGKQAAWISQLIAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSR
YPDCKGTLPVATGTSRRGASRPRRTSGGGRKGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 88
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 75
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 62
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-167 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 6e-169 50
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 6e-169 50
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 4e-169 50
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 4e-165 49