Gene Information

Name : guaA (RSal33209_1755)
Accession : YP_001624904.1
Strain : Renibacterium salmoninarum ATCC 33209
Genome accession: NC_010168
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1517663 - 1519252 bp
Length : 1590 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGACTATCCCCGCCCAAGCGCAGACTTCCCATCGCCCGATTCTGGTTGTCGACTACGGCGCCCAGTACGCGCAGCTGAT
TGCACGTCGGGTCCGTGAGGCCAACGTCTATTCCGTGATTGTGCCGCATACCTTCAGCACCGAGCAGTTGTTGGCTAAGA
ATCCGGCCGCGATCATCCTTTCCGGAGGCCCCTCGAGTGTGTACGCCGAGGGAGCCCCTTCGGTTGGAGCAGATCTTTTC
GAAGCAGGCGTGCCGGTTTTCGGTATTTGCTATGGCTTTCAAGCAATGGCCCTGGCGCTTGGCGGAACAGTTGCGCAGAC
TGGGTTGCGCGAATATGGTGCCACTGATGTGACTTCTGCTGGTGCATCGCGCTCCATTTTGGCCGGAACGCCGGATCAAC
AAAATGTTTGGATGAGTCACGGCGACTCCGTGCAGGAAGCGCCCGCTGGATTTGAAGTTCTGGCCAGTACCTCTGGTGCT
CCGGTAGCCGCTTTTTCAAACCCAGAGAAATGCCTTTACGGTGTGCAGTGGCACCCTGAAGTGAAGCATTCTAATTTTGG
TCAGAAAGTTTTGGAGAACTTCCTCTTCAACGAAGCGAAGCTTGAGCCTAACTGGACCACCGGCAACGTTATTGAAGAGC
AAGTTGAGCGAATTCGCGCCCAGGTCGGCAGCGGAAAAGTTATCTGCGGGCTTTCTGGCGGCGTGGATTCGGCGGTTGCC
GCAGCCTTGGTGCAGCGCGCCGTCGGAGATCAATTGACCTGCGTTTTCGTTGACCATGGCCTACTTCGTGAAGGTGAGGC
CGAGCAGGTCGAACGTGATTTCGTGGCAGTAACCGGAGTCAACCTCTACGTGGCTCGTGAAGCCGATCGATTCCTGGACG
CGCTCGCTGGTGTGAGCGATCCGGAGACAAAACGTAAGATTATTGGTCGCGAATTCATTCGTTCCTTCGAAGAAGCCGAG
CGGGCGCTGGTCGCCCAGGCTGGTCAAGACGGCGAGCAGATCAAGTTCTTGGTCCAAGGCACGCTGTACCCCGACGTCGT
CGAGTCCGGCGGTGGCGAGGGTGCTGCGAACATCAAGAGCCACCACAATGTGGGTGGACTGCCTGATGACTTGCAGTTCG
ATTTAGTTGAACCGCTTCGTGCGCTTTTCAAAGATGAAGTCCGTTCGGTTGGCGCCCAATTGGGCTTGCCTGCCGAAATC
GTTGGCCGTCAGCCATTCCCCGGACCTGGCTTAGGCATCCGGATCGTTGGCGAGATTACCTTGGAACGGCTCGAACTGCT
CCGTAAAGCGGACGCAATTGCGCGCGCCGAGCTCACGGCGGCAGGTCTCGATAACGAAGTGTGGCAAATGCCGGTTGTGC
TGCTGGCCGACGTCCGCAGCGTTGGTGTCCAGGGTGATGGCCGGACTTATGGCCACCCGATTGTCTTGCGACCGGTCTCC
AGTGAGGACGCTATGACGGCCGATTGGTCCAGGCTTCCGTACGATTTGCTGGCCCGGATTTCCAACCGAATTACTAACGA
GGTCGACGGCGTCAATCGCGTAGTGTTGGATGTCACCAGCAAGCCGCCGGGAACCATTGAGTGGGAGTAA

Protein sequence :
MTIPAQAQTSHRPILVVDYGAQYAQLIARRVREANVYSVIVPHTFSTEQLLAKNPAAIILSGGPSSVYAEGAPSVGADLF
EAGVPVFGICYGFQAMALALGGTVAQTGLREYGATDVTSAGASRSILAGTPDQQNVWMSHGDSVQEAPAGFEVLASTSGA
PVAAFSNPEKCLYGVQWHPEVKHSNFGQKVLENFLFNEAKLEPNWTTGNVIEEQVERIRAQVGSGKVICGLSGGVDSAVA
AALVQRAVGDQLTCVFVDHGLLREGEAEQVERDFVAVTGVNLYVAREADRFLDALAGVSDPETKRKIIGREFIRSFEEAE
RALVAQAGQDGEQIKFLVQGTLYPDVVESGGGEGAANIKSHHNVGGLPDDLQFDLVEPLRALFKDEVRSVGAQLGLPAEI
VGRQPFPGPGLGIRIVGEITLERLELLRKADAIARAELTAAGLDNEVWQMPVVLLADVRSVGVQGDGRTYGHPIVLRPVS
SEDAMTADWSRLPYDLLARISNRITNEVDGVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-175 70
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-130 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-130 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-130 50