Gene Information

Name : tktA (ACL_0062)
Accession : YP_001620079.1
Strain : Acholeplasma laidlawii PG-8A
Genome accession: NC_010163
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 68248 - 70203 bp
Length : 1956 bp
Strand : +
Note : transketolase requires thiamine pyrophosphate as a cofactor

DNA sequence :
ATGGATATAAACAAGTTATCTATTGATACGATTCGTTTTTTAGGGATTGACGCTATTAATAAAGCAAATAGTGGACATCC
TGGTATTGTCATTGGTGCTGCACCAATGGCGCATACTCTATTTACAAAACACATCAACATTTATCCAAAGATGAGTCGCT
GGATAAACCGTGACCGCTTTATTCTTTCTGCAGGTCATGGTTCTATGCTACTTTATGCATTAAATCATTTATCGGGTTAC
AAAGTCTCTATTGATGATTTAAAAAACTTTAGAAACTATCCAGGAAATACACCAGGACATCCAGAGTATGGTCATACAGA
TGGTGTTGAAACAACATCTGGTCCGCTTGGACAAGGTATTTCTAATGCTGTGGGTATGGCAATTGCTGAAAAGCATTTAG
CTGCACGTTTTAATGAACCAAACTTTGATTTAATCAGTCACTATACTTATGTATTAGTAGGTGATGGTGACTTACAAGAA
GGGGTAGCTTTAGAAGCTATTTCACTTGCGGGACATTTAGGGTTAGGTAAACTTATTGTTTTATATGATTCTAATGATAT
TCAATTAGACGGTGAAACAAATCTAGCAATATCAGAAGATGTTAAAAAGAAGTTTGAAGCACAAAACTGGCACTACACTA
AAGTAGAAGACGGTGAAGATTTAGATCAAATTAACCGCGCTATTTTACGGGCTAAAAAGATCGTTGATAAACCAACCATT
ATTGAAGTTAAAACAATTATTGGTAGAGGTACAACATCAGAAGGTACTTCAAAAGTTCATGGTTCACCTTTAGGGGAAGC
TGAACGTGAAAAATTAGCACAAAAATCAGGCTATAACTACAAACCATTTGAAGTAGACGGTGAAGTATATAGTTTCTATA
AGAGCAAAGTATTTAACAAAGGTAAACGTGTCTACAACAAATGGGTTAAGATGTTAGATGCTTATAAAGCACAATTCCCA
GAAAAACATGATTTATTCAACCAATTCTTAAGTGGAAATATGCAAATAGATTTAAGTAGCCTAGTATATAATGCAGGTTC
TAAAGAAGCAACACGTAACGTATTAGGTAAAGCTTTAACACTTGCAAGTCATCAAAACTTAAATATTGTTGGTGGATCAG
CAGATCTAACTTCATCAACTAAAGCTAAAGGTAATGATGGACATTTCAGTAGAGATAATGCTTTAGCAAGAAATATTAAC
TTTGGTGTTAGAGAACACGCAATGGGTGCTGTAGTTAATGGTATGACACTGCATGGTGGTTTAAAATCATTTACAGGTGC
ATTCTTTGTCTTCTCAGACTATATGAAACCACCAATTCGTTTAGCTGCAATGATGAAAATACCTAGTGTATTTATCTTCT
CACATGACTCAGTTGCAGTTGGTGAAGACGGTCCAACACATGAACCGATTGAACAACTTATTGGATTACGTAGTATTCCA
GATTTAAACGTTATTCGTCCAGCGGATGCAAATGAAACAAAAGCAGCAGTTGAGATTGCATTTGAATCTAAAGATACAGC
AACAGCGATTATCACTTCTAGACAAAATGTCTTAAATTTAGAACACACAAGTAAAGAGGGTGTTTTAAAGGGAGCATATA
TCGTAAGTAAAGAAGAAAACAAATTAGACGGTATCTTATTAGCATCTGGTTCTGAAGTGGGACTAGCTTATGAAGCAAAA
CAAATCCTTAAAGAAAAAGGATTAGATATCCGTGTTGTTTCTATGCCATCACATCATGCATTTTTATTGCAAAATGAAGA
CTACAGAAGTAAAATACTTCCGGCAAATGTCAAAACCCTTGCAGTAGAGATGGGATCTAGCTATTCATGGTATAGATTTA
CACCTCATGTATACGGTATTGATACATTTGGACTTTCTGCAAATGCTGATGTGGTATTAAAACATTTCGGCTTTAACAAA
GAAAGCATTGCAGAAGCATTTATAAATATTAAATAA

Protein sequence :
MDINKLSIDTIRFLGIDAINKANSGHPGIVIGAAPMAHTLFTKHINIYPKMSRWINRDRFILSAGHGSMLLYALNHLSGY
KVSIDDLKNFRNYPGNTPGHPEYGHTDGVETTSGPLGQGISNAVGMAIAEKHLAARFNEPNFDLISHYTYVLVGDGDLQE
GVALEAISLAGHLGLGKLIVLYDSNDIQLDGETNLAISEDVKKKFEAQNWHYTKVEDGEDLDQINRAILRAKKIVDKPTI
IEVKTIIGRGTTSEGTSKVHGSPLGEAEREKLAQKSGYNYKPFEVDGEVYSFYKSKVFNKGKRVYNKWVKMLDAYKAQFP
EKHDLFNQFLSGNMQIDLSSLVYNAGSKEATRNVLGKALTLASHQNLNIVGGSADLTSSTKAKGNDGHFSRDNALARNIN
FGVREHAMGAVVNGMTLHGGLKSFTGAFFVFSDYMKPPIRLAAMMKIPSVFIFSHDSVAVGEDGPTHEPIEQLIGLRSIP
DLNVIRPADANETKAAVEIAFESKDTATAIITSRQNVLNLEHTSKEGVLKGAYIVSKEENKLDGILLASGSEVGLAYEAK
QILKEKGLDIRVVSMPSHHAFLLQNEDYRSKILPANVKTLAVEMGSSYSWYRFTPHVYGIDTFGLSANADVVLKHFGFNK
ESIAEAFINIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 7e-121 42
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-122 41