Gene Information

Name : hsdM1 (ACL_0589)
Accession : YP_001620582.1
Strain : Acholeplasma laidlawii PG-8A
Genome accession: NC_010163
Putative virulence/resistance : Unknown
Product : type I site-specific restriction-modification system, M (modification) subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 621423 - 622910 bp
Length : 1488 bp
Strand : +
Note : -

DNA sequence :
ATGGCTGATTTACAATTAGGATTCGAAGATAAGCTATGGCAAATGGCTGATAAGCTTAGAGGTAATATCGAATCATCAGA
ATATAAGCACGTGATATTAGGTCTTGTGTTCCTTAAATACATTTCAGATTCATTTACAGAACGTTATGAAGAAATAAAAG
CAAATTATCCAGGTATGGAAGAAGATAGAGATGCATATGAATCAGAAAATGTGTTTTTCGTACCTAAAGATGCTAGATGG
GAATATATCAAATCTCAAGCGAAACAATCAACCATCGGACAGATTATTGATAATGCAATGGTTCAAATAGAAAAAGAAAA
TGCATCACTAAAAGGTGTATTACCTAAAAACTATGCAAGACCAGAACTAGATAAGACTCGACTAGGTGAACTTATTGATC
TATTCTCATTTAATGTAGGGTCTAAAGAAGCAAGAGCAAAAGATGTACTTGGAAGAGTCTATGAGTATTTTCTTAAAAAG
TTTGGAACAACTGAAGGTGAATTCTATACACCACCAGCAATTGTAAAATTACTTGTAAACATGATTGAACCATATAACGG
TAGAGTTTATGACCCTTGTTGTGGTTCTGGAGGTATGTTTGTACAATCCGCTAAATTCGTTGAAGAACATGCTGGTAAAA
TTGGGAATATTTCTATCTATGGCCAAGAATATGTTGCAACCACATGGCGTTTAGCAAAGATGAATCTAGCTATTCGAGGA
ATTGATGCAAACCTTGGTGAAAGAGATGGGGATACTTTTACTAACGATCAACACAAAACATTAAGAGCTGATTATATCCT
TGCAAACCCACCATTTAACATTAAAGATTGGGGACAACAGCACTTAATCGGAGATAGTAGATGGCAATGGGGAACACCTC
CGGCGACTAATGCTAACTACGCTTGGATATCACATATGATTTCAAAACTAAGCCCAAGAGGTATTGCGGGTTTTGTTTTA
GCAAATGGATCATTATCTACTTCAAGAAGTGAAGAATATGAAATTAGAAAAAAGATACTTGAAGAAGGATTAGTTGATTG
TATCGTAGCAATGCCATCACAACTTTTCTATGATGTATCAATTCCAGTATCATTATGGTTTGTTTCAAAAAATAAAAATG
GTAGAAAAGATAAAGTCTTATTCATTGATGCTCGTAAGATGGGGTATATGGAAACCAGAAAGCATAGAGAACTTACTGAT
GAAGAAAGTGAGAAGATCTATTCAACCTACCATGCATGGAGAGATGATAAGGATTATCAAGATATTGATGGGTTCTGTAA
ATCTGCAACACTTGAAGAAATTAGATCACATGATTATGTTTTAACACCAGGTAGATATGTTGGTATAGAAGAAGTTGAAG
ATGATGGTATTCCATTTGAAGAAAAGATGGAAAAACTGACTTTAGAATTATCTGAGTTATTTGAAGAATCTAAATCTCTT
GAGGAAAAGATCAAAGAGAACTTAAGAGGTATCGGGTATGAGCTTTGA

Protein sequence :
MADLQLGFEDKLWQMADKLRGNIESSEYKHVILGLVFLKYISDSFTERYEEIKANYPGMEEDRDAYESENVFFVPKDARW
EYIKSQAKQSTIGQIIDNAMVQIEKENASLKGVLPKNYARPELDKTRLGELIDLFSFNVGSKEARAKDVLGRVYEYFLKK
FGTTEGEFYTPPAIVKLLVNMIEPYNGRVYDPCCGSGGMFVQSAKFVEEHAGKIGNISIYGQEYVATTWRLAKMNLAIRG
IDANLGERDGDTFTNDQHKTLRADYILANPPFNIKDWGQQHLIGDSRWQWGTPPATNANYAWISHMISKLSPRGIAGFVL
ANGSLSTSRSEEYEIRKKILEEGLVDCIVAMPSQLFYDVSIPVSLWFVSKNKNGRKDKVLFIDARKMGYMETRKHRELTD
EESEKIYSTYHAWRDDKDYQDIDGFCKSATLEEIRSHDYVLTPGRYVGIEEVEDDGIPFEEKMEKLTLELSELFEESKSL
EEKIKENLRGIGYEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 9e-159 64
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 8e-159 63
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 2e-157 63
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-108 46