Gene Information

Name : leuS (ACL_0242)
Accession : YP_001620244.1
Strain : Acholeplasma laidlawii PG-8A
Genome accession: NC_010163
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 237001 - 239412 bp
Length : 2412 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCATAAATATGAACACAGAAAAATAGAAGAAAAATGGCAAAAACATTGGTTAGACAATAAGTTGTTTAAAACCAAAAA
CGATAGATTTCATCAGAAATACTATGTTTTAGATATGTTTCCATACCCTTCGGCCTCAGGACTACATGTAGGGCACATTG
AAGGATATACAGCAACAGATATCGTGTCACGTTTTAAACGTATGCAAGGATATAATGTATTACATCCAATGGGATGGGAT
GCATATGGGTTACCTTCTGAGCAATATGCGCTCGCAACCGGAAAAGATCCAAAATCTTTCACATACCAAAATATTAGTAA
TTTCAAAAGACAAATTATTGAAATGGGTAAAGGTGTAGATTGGGATAAAGAGCTAGCTACAACAGACCCTGAGTATTTTA
AATGGACTCAGTGGATTTTTAAACGCCTTTATGAGAAGGGTTTAGCGGTCTTAAAAGATGTTGAAGTCAACTGGTGTGAA
GGTTTAGGTACAGTACTTGCTAATGATGAAATTGAAATCATTAATGGACAAATGGTATCCGAACGCGGACATTACCCAGT
TATTAAAAAACCAATGCGTCAATGGGTATTAAGAATCACTGAGTATGCAGATCGACTACTTGATGATCTTGCTTTAGTGG
ATTGGCCTGAAAACCTAAAAGAAATGCAACGCAACTGGATTGGTAAATCCAGTGGTGCCGTGATTGAATTTGAAGTGGCA
TCCACAGATTATAAATTTGAAATATTTACTACAAGACCTGATACTATCTACGGTGTGACTTACTGTGTACTTTCCCCAGA
ACACCCACTAGTAGAAAAAATTGTGACTCAAGATGAAGAAAAAGATGTATTAAGATACATTGAACAAACTAAAATGAAGT
CAGATTTAGATCGTATTGCAGATAAATCTAAAACAGGTGTGTTTACTGGTGCTTTTGCAAAACACCCACTAACAAACCAA
TTAATTCCAATTTGGATTGGTGACTATGTACTACCTCAATATGGGATGGGCGCTGTTATGGCAGTACCAGCACATGATGA
TAGAGACTATGAGTTTGCTATGCAATATGGTTTAAACATTATTGAAGTTATTAAAGGTGGTAGCGAAGGTGCTTATACTG
GAGACGGTATCCATCATCACTCAGGCATTATTGATGGTTTATATAATGAAGAAGCTATTGAAAAAATAACTAAACATTTA
GAAGATCGCAAAAAAGGGTACAAACACTACACTTATAAGTTAAGAGACTGGGTATTTAGTCGTCAAAGATATTGGGGTGA
ACCATTCCCTGTAATTTATGATGAAGATGGACAAATTCATTTAGTACCAGATGATGAATTACCACTAGAATTACCTTATC
TTGAATTTATAAAACCAAGTGGAACAGGTGAATCACCACTAGCTAACGCACGTGATTGGTTATATGTAGATATCAACGGT
AAAAAAGGTAGACGTGATACCAACACCATGCCACAACTAGCAGGTTCAAGCTGGTATTATATTGGCTACATCCTAAAATC
TAATTTAGGTTATATCCCACTTGACTCTAAGGAAGCTAAAGCAGTACTTGATCAGTTCTTACCAGTCGATCTTTATGTTG
GTGGAACAGAACATGCAGTAGGTCACTTACTTTATGCAAGATTCTGGCATAAATTCTTCTATGACCTAGGTTTTGTAAGT
TCTAAAGAACCTTTCATGAAACTTGTAAACCAAGGTATGATTTTAGGTGCTGACCACTCTAAGATGAGTAAATCAAAAGG
AAATAGTGTCTCACCCGATGACTTTATTCAAAGTCATGGTGCAGATGCACTAAGACTATTTGAAATGTTTATGGGACCTT
TAGAAGCTGAAAAACCTTGGAGTAATGAAGGACTAGAGGGTGCAAAACGTTTCTTAGACCGTGTTTGGCGAATGTTTGAT
TTTGAAATCACACAACAACCAGTAGATGCGCTTCAAACGGTTTATCACCAAACAGTCAAAAAAGTTACAGAAGATTATGA
AAAGTTAGCATTTAATACTGCAATCTCACAAATGATGATCTTTGTTAATGAAGTTTATAAGACTAAAGTAATTGGTGCAG
CTCAAGCAAGAGGATTCTTAAAATTATTAAATCCAATTGCACCACACTTAACAGAAGAAATTAATGAGACTGTGTTAAAA
CATCATGAAGATTTAGTTTATTCTGAATGGCCAACCTATGATGAATCATTCTTAATTGAAACTGAAGTTGAAGTCGCTAT
CCAAGTAAACGGAAAACTACGTGGTAGACTTCAAGTGAAAAAAGATATGGTCGAAGAAGATCTTAAAAAGTTAGCACTTG
AACATGAAAATGTCATCAAGCATGTTGAAGGATTAACAATTGTTAAAGTTATTGTTATACCAAATAAGATTGTAAATATC
GTCGTAAGATAA

Protein sequence :
MHKYEHRKIEEKWQKHWLDNKLFKTKNDRFHQKYYVLDMFPYPSASGLHVGHIEGYTATDIVSRFKRMQGYNVLHPMGWD
AYGLPSEQYALATGKDPKSFTYQNISNFKRQIIEMGKGVDWDKELATTDPEYFKWTQWIFKRLYEKGLAVLKDVEVNWCE
GLGTVLANDEIEIINGQMVSERGHYPVIKKPMRQWVLRITEYADRLLDDLALVDWPENLKEMQRNWIGKSSGAVIEFEVA
STDYKFEIFTTRPDTIYGVTYCVLSPEHPLVEKIVTQDEEKDVLRYIEQTKMKSDLDRIADKSKTGVFTGAFAKHPLTNQ
LIPIWIGDYVLPQYGMGAVMAVPAHDDRDYEFAMQYGLNIIEVIKGGSEGAYTGDGIHHHSGIIDGLYNEEAIEKITKHL
EDRKKGYKHYTYKLRDWVFSRQRYWGEPFPVIYDEDGQIHLVPDDELPLELPYLEFIKPSGTGESPLANARDWLYVDING
KKGRRDTNTMPQLAGSSWYYIGYILKSNLGYIPLDSKEAKAVLDQFLPVDLYVGGTEHAVGHLLYARFWHKFFYDLGFVS
SKEPFMKLVNQGMILGADHSKMSKSKGNSVSPDDFIQSHGADALRLFEMFMGPLEAEKPWSNEGLEGAKRFLDRVWRMFD
FEITQQPVDALQTVYHQTVKKVTEDYEKLAFNTAISQMMIFVNEVYKTKVIGAAQARGFLKLLNPIAPHLTEEINETVLK
HHEDLVYSEWPTYDESFLIETEVEVAIQVNGKLRGRLQVKKDMVEEDLKKLALEHENVIKHVEGLTIVKVIVIPNKIVNI
VVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 55