Gene Information

Name : folP (sce7624)
Accession : YP_001618273.1
Strain : Sorangium cellulosum So ce 56
Genome accession: NC_010162
Putative virulence/resistance : Resistance
Product : dihydropteroate synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0294
EC number : 2.5.1.15
Position : 10610730 - 10611620 bp
Length : 891 bp
Strand : -
Note : Family membership

DNA sequence :
ATGGGGGTCCTGAACCGCACGCCGGACTCGTTCTCCGACGGCGGTCGCTTTGCGGATGAAGATACGGCTCTCGCGCAGAT
CGATGCGATGCTCTCCGAGGGGGCAGACATGATCGACATCGGCGCGGAGTCGACGCGGCCGGGCGCGCGGCCCGTGCCGG
ATGACGAGCAGATCGCGCGCATCGGCGGGAGCGTGCGCGACGCGGTGAAGAGGGGAGCGGTGGTCTCCATCGACACGACC
TCTCCCGCCGTCGCGGCGCGCGCGCTCGACGATGGCGCGGCCGTGGTCAACTCGATCTCGCTCGACAGCGCGGCGGAGCT
CGGCGCGCTCTGCGCTCGGCGCGGGGCGTCGCTCGTGCTCATGCACAGCCGCGGCCCGATGTCGGCGATGGCCGGCTTCT
CCGCGTACCCCGACGACGCCTACGACGACGTCGTGGCCGACGTGGCCCGCGAGTGGTCGAGCGCCGCCGCGCGGGCGCTC
GAGGCAGGCTTGCCGGAGGGCGAGCTCGTCCTCGATCCGGGCCTCGGCTTCGCGAAGAACGCGCGGCAGTCGCTCGAGCT
GTGCGCCAGGATGCACGAGCTCTGCGCCCTCGGCTTTCCCGTGCTCGTCGGGCCGAGCCGCAAGTCGTTCCTGGCGCGCG
CCGCGGCCTCGGAGGCCGCGGCGCGGGGCGGCGGCGAGGAAGCGCTGCTCGCGCCGCCCCCGGACCGCCTCGGCGGCACC
GTCGCCGCCGCGATCGCGTGCGCCGCGCGCGGCGCCGCGGCCGTCCGTGTCCACGATGTCCGCCCCGTGCGCCAGGCCCT
CGACGTGATGCGCGCGATCGAGCGCGCGGGCGCCGGCGACCGTCGGCGCCCGGACGGCCCCGTCGCCCAGGGGGCGCGAG
CCGATGGTTGA

Protein sequence :
MGVLNRTPDSFSDGGRFADEDTALAQIDAMLSEGADMIDIGAESTRPGARPVPDDEQIARIGGSVRDAVKRGAVVSIDTT
SPAVAARALDDGAAVVNSISLDSAAELGALCARRGASLVLMHSRGPMSAMAGFSAYPDDAYDDVVADVAREWSSAAARAL
EAGLPEGELVLDPGLGFAKNARQSLELCARMHELCALGFPVLVGPSRKSFLARAAASEAAARGGGEEALLAPPPDRLGGT
VAAAIACAARGAAAVRVHDVRPVRQALDVMRAIERAGAGDRRRPDGPVAQGARADG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 2e-12 41
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 1e-12 41
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 1e-12 41
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 2e-12 41
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 2e-12 41
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 2e-12 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
folP YP_001618273.1 dihydropteroate synthase NC_002516.2.881715.p Protein 3e-23 42
folP YP_001618273.1 dihydropteroate synthase CP002695.1.gene1085. Protein 1e-17 41