Gene Information

Name : guaA (sce3679)
Accession : YP_001614319.1
Strain : Sorangium cellulosum So ce 56
Genome accession: NC_010162
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 5147267 - 5148841 bp
Length : 1575 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCTAGCGGCAGCCATGCTCTCACCCCGGCGGGACTTCGTCGTCATCCTCGATTTCGGCTCTCAGTACACGCAGCTCAT
CGCCCGGCGCGTGCGCGAGTCTGGCGTCTACTGCGAGATCCACCGCTTCGACGTGCCCATCGCCGAGCTGCGCCGGCTCG
CCCCTCGGGCGCTCATCCTCTCGGGCGGCCCCGCCAGCGTGTACGGAGACAACGCGCCTCGCTGTTCCCGGGAGGTGCTG
GAGCTCGGCGTCCCGACGCTGGGCATCTGCTACGGGCTCCAGCTCATGGCGTATCACCTCGGCGGCAAGGTCGAGCGCGC
GCACACGGGGGGCGAGTACGGCCCCGCGACGGTGCGCGTCGAGCGCCCGACGGGCATCTTCTCTCGCTTCGCCGAGGGCG
ACGCCATCGACGTCTGGATGAGCCACGGCGATCGGCTCACCGCGATGCCGGAGGGGTTCGTGTCGCTCGGCACCACGACC
GGCAGCCCGCTCTGCGCCGTCGCCCGCGAGCGCGACAAGCTCTACGGCCTCCAGTTCCACCCCGAGGTCGTCCACACGCC
GCGCGGCAAGGAGATCCTCCAGTCCTTCCTGTTCGACGTCGCCGGCCTCTCGCCGACCTGGACGCCCGCGTCGTTCGTGG
AGGAGGCGATCGCCGCGGTCCGCGAGAAGGCCGGGCCGAGCGACCGCGTCATCCTGGGCCTCTCGGGCGGGGTCGACTCG
TCGGTCGCCGCCGTGCTCTGCCAGCGCGCCCTCGGCGACCGGCTGACGTGCATCTTCGTCGACAACGGCCTGCTTCGCGA
GGGCGAGGCGGAGAGCGTCGAGCGGACCTTCCGCGGCCACTTCCACATGAACCTCGACGCCGTCGACGCGTCGGCGCGGT
TCCTCGAGGGGCTGCGCGGCGTCGTGGATCCCGAGCAGAAGCGCAAGGTGATCGGCCGCCTCTTCATCGAGGTGTTCGAG
GAGGAGGCGAAGCGGGTCCAGGGCGCGAAGTGGCTCGTCCAGGGCACGCTCTACCCCGACGTGATCGAGAGCGTCTCGTT
CAAGGGGCCGAGCGCCGTCATCAAGAGCCACCACAACGTCGGCGGCCTGCCCGAGCGGATGAACCTCGGCCTGATCGAGC
CCCTGCGGGAGCTCTTCAAGGACGAGGTGCGGGCCGCCGGCGAGGCGCTCGGCATGCCGCGGGACATCCTGTACCGCCAG
CCGTTCCCCGGCCCGGGGCTCGCGGTACGGTGCCTCGGCGAGGTGACGCCGGAGAAGCTCCGCGTGCTCAGGGAGGCCGA
CGCCATCTTCGACCAGGAGATCCGCGCCGCCGGGCTCTACGAGTCGCTCTGGCAGAGCTTCTGCGTGCTCCTCCCCGTGC
GCTCCGTGGGCGTGATGGGCGACGAGCGCACCTACGACGAGGCGATCGCGCTCCGCGCGGTGCACTCGACCGACGGGATG
ACGGCCGACTGGGCGCGGCTGCCCTACGACCTCATCGCCCGGGTGAGCTCGCGCATCATCAACGAGGTGCGCGGCGTGAA
CCGCGTGGTGCTCGACGTCTCCTCGAAGCCGCCCTCGACGATCGAGTGGGAGTGA

Protein sequence :
MLAAAMLSPRRDFVVILDFGSQYTQLIARRVRESGVYCEIHRFDVPIAELRRLAPRALILSGGPASVYGDNAPRCSREVL
ELGVPTLGICYGLQLMAYHLGGKVERAHTGGEYGPATVRVERPTGIFSRFAEGDAIDVWMSHGDRLTAMPEGFVSLGTTT
GSPLCAVARERDKLYGLQFHPEVVHTPRGKEILQSFLFDVAGLSPTWTPASFVEEAIAAVREKAGPSDRVILGLSGGVDS
SVAAVLCQRALGDRLTCIFVDNGLLREGEAESVERTFRGHFHMNLDAVDASARFLEGLRGVVDPEQKRKVIGRLFIEVFE
EEAKRVQGAKWLVQGTLYPDVIESVSFKGPSAVIKSHHNVGGLPERMNLGLIEPLRELFKDEVRAAGEALGMPRDILYRQ
PFPGPGLAVRCLGEVTPEKLRVLREADAIFDQEIRAAGLYESLWQSFCVLLPVRSVGVMGDERTYDEAIALRAVHSTDGM
TADWARLPYDLIARVSSRIINEVRGVNRVVLDVSSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-126 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-127 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-127 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-127 50