Gene Information

Name : guaA (Btr_0201)
Accession : YP_001608676.1
Strain : Bartonella tribocorum CIP 105476
Genome accession: NC_010161
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 257811 - 259403 bp
Length : 1593 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAATTCTCTTTTTACAATTATTGATTGGTTTTCTATGAGCATATCACATCCAGACGCTGTTCTTATTATTGACTTTGG
CTCACAAGTTACACAACTTATTGCACGACGGGTGCGAGCAATGGGGGTATACTGTGAAATTGTGCCTTTTCAATTGGCTT
TAGAAGCTGTGCGCCGCATAAATCCTCAAGCTATTATTTTATCAGGAAGTCCTTATTCTGTTATTGATGAAGGGTCGCCG
CGTGCTCCAATGGAAATTTTTGAGGCCGGTATTCCGATTCTTGGTATTTGTTATGGGGAGCAGGTCATGTGTGTTCAGCT
TGGAGGAAAGGTTGAAGCTGGACATGAGCGTGAATTTGGTCGTGCTTTTTTGGAAATCCAAGAGGAGAGTGCACTGTTTG
ATGGTGTGTGGGAAAAAGGTTCTCATTATCAAGTATGGATGAGTCATGGTGACCGTGTGGCATCTTTACCAGAAGGTTTT
CGTGTCATAGGAACCTCAAAAGGAGCTCCCTATGCGGCCATTGCTGATGAGAAAAGACGTTTTTATGCGGTACAGTTTCA
TCCTGAAGTAATCCATACACCGGATGGTACAAAACTTTTACAAAATTTTATTCATAGAATCTCTGCGATTAAAGGCAATT
GGTCTATGGCTTCTTATCGTGAGCAGGCAATTGCGACAATACGACAAAAAGTTGGGAAAAATCGTGTGATTTGTGGTCTG
TCAGGGGGAGTGGATTCATCTGTTGTCGCGGTGCTCCTTCATGAAGCCATAGGAGATCAACTGACATGCATTTTGGTCGA
CCATGGATTAATGCGTAAGAATGAGGCTCAGGAAGTTCTTACATTATTCCGTGATCACTATAACATAGAGCTTATTCATG
TTAATGCTGCCGATATATTTCTTAATGCTTTAGAAGGTGAGACAGATCCAGAAAAGAAGCGCAAAACAATAGGGCGCCTT
TTTATTGAAGTTTTTGAAGAAGAAACGAAAAAAATAGGAGGCGCAGAGTTTTTAGCACAAGGGACACTTTATCCAGATGT
TATTGAGAGTGTCTCTGCTATTGGTGAATCGGTGACCATTAAAAGCCATCATAATGTGGGGGGGTTACCAGAACAGATGA
ATATGAAACTTGTAGAACCGTTACGTGAGCTCTTTAAGGATGAGGTTCGCTTGCTAGGACGAGAGCTAGGGTTACCCGAG
CAGTTTATTGGTCGCCATCCTTTCCCAGGTCCAGGTCTTGCAATTCGCTGTCCAGGTGCCGTAACACGCGAAAAATTAGA
AATTTTACGTGAAGCAGATTCCATTTATCTTGAGGAAATCCGTAAGGCTGGTCTTTATGATGAAATTTGGCAAGCTTTTG
CTGTCCTTCTTCCTGTCCAGACTGTTGGAGTGATGGGGGATAGTCGCACGTATGAATTTGTTTGTGCGCTTCGCGCTGTC
ACATCTGTCGATGGAATGACCGCTGATTTTTATCCCTATGATATGGCATTTTTAAGTAAGACCGCCTCACGCATTATTAA
CGAAGTTAGAGGAATTAATCGTGTTGTTTATGATGTAACCTCAAAGCCTCCTGGTACCATTGAATGGGAATAA

Protein sequence :
MNSLFTIIDWFSMSISHPDAVLIIDFGSQVTQLIARRVRAMGVYCEIVPFQLALEAVRRINPQAIILSGSPYSVIDEGSP
RAPMEIFEAGIPILGICYGEQVMCVQLGGKVEAGHEREFGRAFLEIQEESALFDGVWEKGSHYQVWMSHGDRVASLPEGF
RVIGTSKGAPYAAIADEKRRFYAVQFHPEVIHTPDGTKLLQNFIHRISAIKGNWSMASYREQAIATIRQKVGKNRVICGL
SGGVDSSVVAVLLHEAIGDQLTCILVDHGLMRKNEAQEVLTLFRDHYNIELIHVNAADIFLNALEGETDPEKKRKTIGRL
FIEVFEEETKKIGGAEFLAQGTLYPDVIESVSAIGESVTIKSHHNVGGLPEQMNMKLVEPLRELFKDEVRLLGRELGLPE
QFIGRHPFPGPGLAIRCPGAVTREKLEILREADSIYLEEIRKAGLYDEIWQAFAVLLPVQTVGVMGDSRTYEFVCALRAV
TSVDGMTADFYPYDMAFLSKTASRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-140 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-140 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-140 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-116 50