Gene Information

Name : thyA (Btr_1568)
Accession : YP_001609902.1
Strain : Bartonella tribocorum CIP 105476
Genome accession: NC_010161
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 1667914 - 1668708 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAATCATATCTTGCTCTTTTATCTCATGTTTTAAATCAGGGTATTGATCGGACAGATCGGACGGGTGTTGGGACGCG
ATCTATTTTTGGGTATCAGATGCGTTTTGATTTACAAGCGGGATTTCCGTTGTTGACGACAAAGAAACTACACTTACGTT
CAATTATTTATGAGCTTTTGTGGTTTCTTAAAGGCGATACAAATATCGCATGGTTGAAAGAGCATGGTGTATCTATTTGG
GACGAATGGGCTGATAAACAAGGAAATCTTGGTCCTGTTTATGGGTATCAGTGGCGTTCTTGGCCTGCTCCTGATGGACG
CCATATTGATCAAATTGACAATCTTTTAAGGATGATTAAGGAAAAGCCGGATTCTCGTCGCTTGATTGTATCAGCTTGGA
ATCCCGCATTAATAGAGGAAATGGCTTTGCCTCCTTGCCATTGTCTTTTTCAATTTTACATTGATGAGGGTAAATTGTCC
TGTCAGCTTTACCAGCGTTCAGCGGATATTTTTTTAGGGGTTCCATTCAATATTGCGTCTTACGCATTGTTAACGATGAT
GATCGCGCAAGTCAGTGGCCTTAAAGTAGGTGATTTTATTCATACGTTCGGGGATGCTCATCTTTATTCTAATCATTTTG
AACAGGCACAATATCAATTGTCTCGTATACCCAATGCTTTGCCATGTATGCGCATAAATCCAGCGGTAACAGATCTTTTT
TCTTTTAAATTTGAGGATTTTGAATTGCTTAATTATGAAGCACATCCCCATATTAAAGCGCCGGTAGCAATATGA

Protein sequence :
MKSYLALLSHVLNQGIDRTDRTGVGTRSIFGYQMRFDLQAGFPLLTTKKLHLRSIIYELLWFLKGDTNIAWLKEHGVSIW
DEWADKQGNLGPVYGYQWRSWPAPDGRHIDQIDNLLRMIKEKPDSRRLIVSAWNPALIEEMALPPCHCLFQFYIDEGKLS
CQLYQRSADIFLGVPFNIASYALLTMMIAQVSGLKVGDFIHTFGDAHLYSNHFEQAQYQLSRIPNALPCMRINPAVTDLF
SFKFEDFELLNYEAHPHIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-79 61