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Name : YpAngola_A3944 (YpAngola_A3944) Accession : YP_001608241.1 Strain : Yersinia pestis Angola Genome accession: NC_010159 Putative virulence/resistance : Virulence Product : two-component sensor/regulator Function : - COG functional category : T : Signal transduction mechanisms COG ID : COG0642 EC number : - Position : 4192916 - 4195591 bp Length : 2676 bp Strand : + Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01627; match to protein family HMM PF02518 DNA sequence : ATGGCATCGATGCGGGCGGACTTAAGTAATCACCAGTTTGAAGGAGCTGAACGTGATGCCGCCTCGTTAATAAGCCGACG AGAAAGCCTCCAGAGCACCTCACCGTTGCCTGAAATATCGATAAAACATTATGATAGCTACTATATTCCCTTTAATCTGG ATAGCTGTAATATTAACCAACATAAAAATGATCTGTGGATAATTCAAGCGTATGGCACCGCCGGACAAACTTATTATCTC GACAGTTTTATTATCAAACAAAAAGAGGGGATTGTGTTATTCCCACCCCAAAAATCATCGAGTGATTACCTAAATCAACG GCGCAAAGATTTACTTTTGCTCCCCAAATTTCCTACTCACAATAATATCTATTGGGGAGCCCCCACCTATACGCCTCAAG GTGGCTGGCATGTTTCTGTCGCGGTGTGTGATAAAGTGGGCACCTTAGCTGGCTTCGCCTTAAAACTGAATGATCTCATC GCCTATAATCACCCTGTCGAGCAAAGAGACATTAATTTATTGTTGGATAAGAATGGTGAATTATTGCCTATTTCCCAGCA AGCAACATCATCAAATCAACTGCATGAAATTCTTAACCAACTCAAAAACAGTAAATTACACGATGGCTGGCAGCAAACTC CCGACTATTTGGTATTACGCACCCAATTGAAAGGGCCGGGTTGGCAGCAATTAGTTATTTATCCGCGAATGGGCTTTGCC TGGGAGGCACTGAAACCCGCCTTATATCAACTCCCTTTCGCTCTGGCTATTTTACTGTTGCTCACGTCAGTACTGTCACT GCTGCTGCGATATTATCTGGCGATCCCTTTGTGGAATTTCATCAATATCATTGGCGCTACCGGGCCACAGGCAATGGAAC CCCGACTTCCCATAAACCGAATAGATGAATTAGGGCATATTGCCCGCGCTTATAACAACTTACTGGATACGTTGAACGAA CAATATGACACCTTAGAAATGAAAGTGAAGGAGCGCACTCTGGCTCTGGCGGAAGCCAAGCGAGCGGCTGAGCAGGCTAA CCGCCGTAAAAGCGACCATCTGACCACGATCAGCCATGAAATCCGTACACCGCTCAACGGGGCGTTGGGGGCGGTTGAAT TATTACAAAATACACCACTGGATGCTGGCCAAATGAGGTTAGCGGAAACGGCCCACCAATGTTCGTTGTCACTGCTCGCG ATCATTAACAACCTGTTAGATTTTTCACGTATTGAATCAGGGCAGATGACACTGTCGCTGGAGAAAACGGCCCTACTGCC TTTACTGGATCAGGCGATGTTAACCATTCATAGCCAGGCACTGAGTAAGTCATTAGCGCTGTCCACGTTTATCAGTGCCA ATATCCCGCTGGAACTTGAGCTGGATACACTGCGCTTAAGACAGATTCTGGTTAATTTATTAGGTAATGCCGTTAAATTC ACACCACAGGGCCGTATTCAACTCAGGGTCAGGCGTCAAAACCAAACGCTTTGTTTTACCGTTGAGGACACCGGTTGTGG TATTGACGTGCAACACCAACAAACAATATTCCAACCTTTTATGCAGACCAGTGACCATGAACAAGGAACGGGTTTGGGGC TGGCTATCGCAGATAATCTGGCCAAAATGATGGGAGGGCACCTGACAGTATTCAGTGAACCGGGTCAAGGTAGCTGTTTT TCATTATGCCTCCCCTTCAATGCAATCACCCCGCCAATGCCTTTTCATGGCGAGCTATTCGCACCACAACGCTTACACGC CCAATTATCAGCCTGGGGCATGACCTGCCAGCCAGAATTAGCTAATCAGCCATCACGGCACTTTGTGGATAACGCATTGT GTTACTTACCCGGCCGGTTATACGCCAAGCTGAAACAATATCTACAAGGTGCTGAGACTGAAGCGCTAAAGAGCCTTCCG CTGCAACCTTGGCAGATGCACATTCTATTGGTTGATGACTCCGAAACTAATCGCGATATTACCGGAATGATGTTGCAGCA ACTGGGGCATCAGGTCACGCGGGCAGACAGTGGCACAACCGCATTGGCGATTGGCCGCCAACACCGTTTCGATTTAGTGC TAATGGATATTCGAATGCCTGTCCTGGACGGGCTGGCCACCACAGCACGCTGGCGTCATGATCCGGCGAACATTGATAGC CACTGCATGATCACCGCCCTGAGCGCCAATGCCAGCCCGGATGAGCAAATCAAAACCAGTCAGGCGGGGATGAATCACTA CCTTTCCAAGCCTGTCACCCTCGGCCAATTGGCTGAAATGTTAGATCTGACCGCACAATTCCAGCTTGAGCGTGGGGTCG ATCTATCACCACAACTCTCCGAGCCTCAGCCATTACTGGATCTCGCGGACAGCGCGTTGTCCCTGAAACTTTATCAATCA CTGCAAGTATTAATTCAACAGGCCAAAGACGCTATTGAGAACTTGCCCGTATTATCCCATACGCTTCACACCATAAAAGG CTGTGCCGGGCAAGCTGGGCTAATTGAATTACAAGATGCGGTCATTCAATTAGAACACGCTCTCGATACTCATGAAACGC TGACACAGCAAGAGATCATTCAACTTGATGAAATAATTCATGTGCTGCTACAGCCCCCCACTACCTGCGAATCCACGTTT ATCATCAGCCAGGGCCAGTCCCTTATGGTTAAATAA Protein sequence : MASMRADLSNHQFEGAERDAASLISRRESLQSTSPLPEISIKHYDSYYIPFNLDSCNINQHKNDLWIIQAYGTAGQTYYL DSFIIKQKEGIVLFPPQKSSSDYLNQRRKDLLLLPKFPTHNNIYWGAPTYTPQGGWHVSVAVCDKVGTLAGFALKLNDLI AYNHPVEQRDINLLLDKNGELLPISQQATSSNQLHEILNQLKNSKLHDGWQQTPDYLVLRTQLKGPGWQQLVIYPRMGFA WEALKPALYQLPFALAILLLLTSVLSLLLRYYLAIPLWNFINIIGATGPQAMEPRLPINRIDELGHIARAYNNLLDTLNE QYDTLEMKVKERTLALAEAKRAAEQANRRKSDHLTTISHEIRTPLNGALGAVELLQNTPLDAGQMRLAETAHQCSLSLLA IINNLLDFSRIESGQMTLSLEKTALLPLLDQAMLTIHSQALSKSLALSTFISANIPLELELDTLRLRQILVNLLGNAVKF TPQGRIQLRVRRQNQTLCFTVEDTGCGIDVQHQQTIFQPFMQTSDHEQGTGLGLAIADNLAKMMGGHLTVFSEPGQGSCF SLCLPFNAITPPMPFHGELFAPQRLHAQLSAWGMTCQPELANQPSRHFVDNALCYLPGRLYAKLKQYLQGAETEALKSLP LQPWQMHILLVDDSETNRDITGMMLQQLGHQVTRADSGTTALAIGRQHRFDLVLMDIRMPVLDGLATTARWRHDPANIDS HCMITALSANASPDEQIKTSQAGMNHYLSKPVTLGQLAEMLDLTAQFQLERGVDLSPQLSEPQPLLDLADSALSLKLYQS LQVLIQQAKDAIENLPVLSHTLHTIKGCAGQAGLIELQDAVIQLEHALDTHETLTQQEIIQLDEIIHVLLQPPTTCESTF IISQGQSLMVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| YPO0256 | YP_002345336.1 | two-component sensor/regulator | Not tested | Not named | Protein | 0.0 | 100 |
| spiR | AAC44299.1 | SpiR | Virulence | SPI-2 | Protein | 8e-137 | 47 |
| ssrA | NP_456136.1 | putative two-component sensor kinase | Virulence | SPI-2 | Protein | 6e-144 | 45 |
| ssrA | NP_805063.1 | two-component sensor kinase | Virulence | SPI-2 | Protein | 2e-144 | 45 |
| ssrA | YP_216400.1 | secretion system regulator:sensor component | Virulence | SPI-2 | Protein | 1e-144 | 45 |
| ssrA | NP_460357.1 | sensor kinase | Virulence | SPI-2 | Protein | 1e-143 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| YpAngola_A3944 | YP_001608241.1 | two-component sensor/regulator | VFG0493 | Protein | 5e-144 | 45 |
