Gene Information

Name : metB (YpAngola_A3807)
Accession : YP_001608116.1
Strain : Yersinia pestis Angola
Genome accession: NC_010159
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4040144 - 4041304 bp
Length : 1161 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACGCGTAAACAGGCAACAATAGCAGTCCGTAGCGGGTTGAATGATGACGAGCAATACGGCTGCGTTGTCCCCCCGAT
TCACCTTTCCAGTACCTACAATTTTATTGATTTTAATCAGCCGCGCACGCATGACTATTCACGTCGTGGTAATCCAACGC
GTGATGTTGTCCAACGGGCGCTGGCGGAATTGGAAGGGGGGGCCGGTGCCGTCATGACCAGCAGCGGGATGTCGGCGCTT
CATTTGGTTTGCACTACATTCTTACAGCCGGGCGATCTGTTGGTCGCTCCGCATGACTGTTACGGTGGCAGTTACCGTTT
ATTTGACAGCTTGAGCAAGCGTGGTGCGTATCGGGTGTTATTTGTTGATCAGGGCGATGAAGCGGCACTAAACTGCGCAT
TGGAGGAGAAACCGAAGTTGGTCTTGATTGAAACACCGAGTAATCCATTGCTACGGGTTGTTGATATTGCCGCCATCTGC
CAAGCCGCCCGTGCTGCGGGCGCACTGACGGTTTGTGATAACACCTTCCTCAGCCCCGCCTTACAGCAGCCTCTCTCTCT
TGGGGCCGATTTAGTGGTGCACTCCTGTACCAAATATCTCAATGGTCACTCTGATGTGGTGGCTGGTGCTGTTATTGCGA
AAGATCCAGAACTGGTTGTCGAGCTGGCATGGTGGGCAAATAATATTGGTGTAACCGGTGCTGCGTTTGACAGCTATCTA
CTCCTTCGTGGTTTACGCACGTTATCACCACGCATGGCTCAACAGCAGCGTAACGCGGATGACATTGTGCGTTATTTACA
GCAACAGCCTTTAGTGAAAAAGCTGTATCATCCTTCCCTGCCACAACATCCCGGCCACGAAATAGCCTGCCGTCAGCAAT
CAGGTTTTGGTGCAATGCTCAGTTTTGAGCTGGATGGTGATGAGCAGGTCATGCGCCGTTTCCTTTCTGCCCTTGAGCTA
TTTACCTTGGCAGAGTCTTTGGGGGGGGTAGAAAGCCTGATCTCCCATGCAGCGACCATGACCCACGCGGGTATGGCGGC
AGAGGCGCGTATTGCCGCAGGCATTACTGATAGTTTGTTGCGTATTTCCGTGGGTATTGAAGACAGTGAAGATTTGATTG
CTGATTTGGACCACGCGTTCCAATTGGCAGTAACGAGGTAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFIDFNQPRTHDYSRRGNPTRDVVQRALAELEGGAGAVMTSSGMSAL
HLVCTTFLQPGDLLVAPHDCYGGSYRLFDSLSKRGAYRVLFVDQGDEAALNCALEEKPKLVLIETPSNPLLRVVDIAAIC
QAARAAGALTVCDNTFLSPALQQPLSLGADLVVHSCTKYLNGHSDVVAGAVIAKDPELVVELAWWANNIGVTGAAFDSYL
LLRGLRTLSPRMAQQQRNADDIVRYLQQQPLVKKLYHPSLPQHPGHEIACRQQSGFGAMLSFELDGDEQVMRRFLSALEL
FTLAESLGGVESLISHAATMTHAGMAAEARIAAGITDSLLRISVGIEDSEDLIADLDHAFQLAVTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-51 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-53 43