Gene Information

Name : tkt (YpAngola_A3352)
Accession : YP_001607695.1
Strain : Yersinia pestis Angola
Genome accession: NC_010159
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 3566261 - 3568255 bp
Length : 1995 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCCTCTCGTAAAGAGCTTGCCAACGCTATCCGCGCACTAAGCATGGATGCCGTGCAAAAAGCGAAGTCCGGCCATCC
CGGAGCCCCGATGGGTATGGCAGATATTGCCGAAGTCCTGTGGCGTGATTATCTGAACCATAATCCAACTAACCCACACT
GGGCTGATCGTGACCGTTTCGTCCTGTCAAATGGTCACGGCTCCATGTTGATTTATAGCCTGTTGCATCTCACAGGTTAT
GACCTGCCGATGGAAGAGCTAAAAAATTTCCGCCAACTGCACTCTAAAACGCCTGGCCACCCTGAATATGGTTATACCGC
TGGTGTAGAAACCACCACTGGGCCATTGGGGCAAGGCATTGCCAATGCTGTTGGTTTTGCTATCGCAGAACGCACGCTGG
GGGCGCAGTTTAACCGCCCAGGTCACGACATTGTCGATCACCATACCTACGCCTTTATGGGCGATGGTTGCATGATGGAA
GGGATCTCTCACGAGGTTTGCTCTCTGGCCGGTACGATGAAGCTGGGCAAACTGACGGCTTTCTATGATGACAACGGTAT
TTCTATCGATGGTCATGTTGAAGGCTGGTTCACTGATGACACGGCGGCCCGTTTCGAAGCCTACGGCTGGCATGTGGTAC
GGGGTGTTGATGGCCATAACGCGGACTCTATTAAAGCGGCTATCGAAGAAGCACATAAGGTTACCGACAAGCCTTCATTG
TTGATGTGCAAAACGATTATTGGTTTTGGCTCACCAAACAAAGCTGGAACCCATGATTCCCATGGTGCGCCATTAGGTGA
AGCGGAAGTGGCAGCAACCCGTGAAGCATTAGGTTGGAAATACCCGGCATTTGAAATCCCACAAGATATCTATGCGGCAT
GGGATGCCAAAGAAGCGGGCAAAGCCAAAGAAGCGGCCTGGAACGAGAAGTTCGCTGCGTATGCCAAGGCTTATCCAGAA
CTGGCGGCTGAATTCAAACGTCGTGTCAGCGGTGAATTACCGGCTAACTGGGCCGTTGAATCCAAGAAATTCATCGAACA
ATTGCAAGCCAATCCAGCAAATATTGCCAGCCGCAAAGCCTCACAAAATGCGCTGGAAGCCTTCGGTAAAGTGTTACCTG
AGTTCCTGGGCGGTTCTGCTGACCTGGCACCGAGTAACCTGACTATCTGGTCTGGCTCTAAATCCTTGAGCGACGATCTG
GCTGGTAACTACATTCACTACGGTGTCCGTGAATTTGGTATGTCTGCCATCATGAACGGTATTGCCCTGCACGGCGGTTT
CATCCCTTACGGCGCAACCTTCCTGATGTTTGTGGAATATGCCCGTAACGCAGTGCGCATGGCGGCACTGATGAAAATCC
GTAGCGTGTTCGTTTATACCCATGACTCTATTGGTCTGGGCGAAGATGGCCCAACCCATCAGCCTGTTGAACAGATGGCC
AGCCTGCGTGTTACCCCGAATATGAGTACCTGGCGTCCTTGTGATCAGGTCGAATCTGCAGTGGCATGGCAGTATGCGCT
GGAACGTAAAGATGGCCCAAGCGCACTGATCTTCTCCCGACAGAATCTGGCACAGCAGCCACGTACTGCGGAGCAGCTAG
CCAATATCGCCAAAGGCGGGTATGTGCTGAAGGATTGTGCAGGCCAGCCTGAACTGATCCTGATTGCTACCGGCTCTGAA
GTGGAGTTAGCAGTTGCTGCGGCTGATCAACTGACGGCCACTGGCCGTAAAGTCCGCGTTGTCTCTATGCCATCAACTGA
TGCATTCGATAAACAAGATGCGGCTTACCGTGAGTCAGTATTGCCATCTGCGGTTAGCGCACGTGTTGCCGTAGAAGCGG
GTATTGCGGATTATTGGTACAAATACGTTGGCCTGAATGGCGCGGTTGTCGGTATGACCACGTTTGGTGAATCAGCGCCA
GCTGAATTGCTGTTCAAAGAGTTTGGTTTCACCGTGGAAAACGTGGTGGCGAAAGCTCAGGCGCTGCTGAAGTAA

Protein sequence :
MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDYLNHNPTNPHWADRDRFVLSNGHGSMLIYSLLHLTGY
DLPMEELKNFRQLHSKTPGHPEYGYTAGVETTTGPLGQGIANAVGFAIAERTLGAQFNRPGHDIVDHHTYAFMGDGCMME
GISHEVCSLAGTMKLGKLTAFYDDNGISIDGHVEGWFTDDTAARFEAYGWHVVRGVDGHNADSIKAAIEEAHKVTDKPSL
LMCKTIIGFGSPNKAGTHDSHGAPLGEAEVAATREALGWKYPAFEIPQDIYAAWDAKEAGKAKEAAWNEKFAAYAKAYPE
LAAEFKRRVSGELPANWAVESKKFIEQLQANPANIASRKASQNALEAFGKVLPEFLGGSADLAPSNLTIWSGSKSLSDDL
AGNYIHYGVREFGMSAIMNGIALHGGFIPYGATFLMFVEYARNAVRMAALMKIRSVFVYTHDSIGLGEDGPTHQPVEQMA
SLRVTPNMSTWRPCDQVESAVAWQYALERKDGPSALIFSRQNLAQQPRTAEQLANIAKGGYVLKDCAGQPELILIATGSE
VELAVAAADQLTATGRKVRVVSMPSTDAFDKQDAAYRESVLPSAVSARVAVEAGIADYWYKYVGLNGAVVGMTTFGESAP
AELLFKEFGFTVENVVAKAQALLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 88
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 71