Gene Information

Name : lipA (NMCC_0090)
Accession : YP_001598266.1
Strain : Neisseria meningitidis 053442
Genome accession: NC_010120
Putative virulence/resistance : Virulence
Product : capsule polysaccharide modification protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 88025 - 90139 bp
Length : 2115 bp
Strand : +
Note : Code: M; COG: COG3563

DNA sequence :
ATGTTCCTCTTTTCAGACGGCCTACAATCTATTAATAACAATAATCGACGAAAACGCATTGTGAAAAACGCCTACATCCC
CTCTCGCGGCATCCGCAAAATCCCCCATCTCTCCACCCTATTGCCCGAGTTTCATATCTACAAAGACGGAAAAGGAGCAG
AGGCTGTTGTCGGCTGGGGTTTGCGCCCGACGACACACAAAGCGCGTGCTTTTGCCACCGAACACCAGCTTCCCTTTATT
GCTTTGGAAGACGGCTTTTTACGCTCGCTCGGACTGGGCGTCTCCGGTTATCCCCCCTACTCCATCGTCTATGACGACAT
CGGCATCTACTACGACACTACCCGCCCTTCTCGTTTGGAACAACTGATTCTTGCCGCCGATACCATGCCGTCTGAAACCT
TGGCTCAGGCGCGGCAGGCGATGGATTTCATCCTGCAACACCATCTGTCCAAATACAACCACGCGCCCGAACTTTCAGAC
GATCATCCTTTACGCTCCCCATCCAAGTCTGAAACCGTCCTCATTATCGACCAAACCTTCGGCGATATGGCTATCCAATA
TGGCGGTGCAGACGCCTCTACGTTTGAATTGATGTTTCAGACGGCCTTAAATGAAAACCCGCAAGCCGATATTTGGGTCA
AAACCCATCCCGATGTTTTGTGCGGCAAAAAACAAGGCTATCTGACCCAGCTTGTGCAGCAACACCGCGTCCATCTTCTG
GCAGAAGACATCAATCCGATTTCTTTGTTGCAAAACGTCGATAAAGTTTATTGCGTTACCTCGCAAATGGGTTTTGAGGC
GCTTTTGTGCGGCAAGCCGCTGACCACTTTCGGCCTGCCGTGGTATGCCGGATGGGGCGTGAGTGACGACCGCCACCCAA
AAATCGGCAGCCTTATTCAAACCCAACGCCGCGCCCCCCGCAACTTGCTGCAACTCTTCGCCGCAGCCTATCTGCAATAC
AGCCGCTACCTCAATCCCAATACCGGCGAAGCAGGCAGCCTCTTTGATGTCATCGACTATCTGGCGACGGTCAAACGTAA
AAACGACAAATTGCGTGGCGAGTTATATTGCGTCGGTATGTCTTTGTGGAAACGCGCGGTTGCCAAACCGTTCTTTAACG
TACCCTCTTGCCGTCTGAAATTTATCTCTTCCACCCAAAAACTGGCAAGGGTCAAACTGTCCGACGATGCACGCATCCTG
GCTTGGGGCAACGGCAAAGAGGCCATCGTCCGCTTTGCCGAACAACACCACATCCCCCTGCTGCGCATGGAAGACGGCTT
TATCCGCTCGGTCGGACTCGGCTCCAACTTAGTGCCGCCGCTGTCGCTCGTTACCGACGATATGAGCATTTATTTCAATG
CCGAAACCCCGTCCCGTCTTGAATACATCCTACAAAACCAAAACTTCGACGATCAAGACTTTCAGACGGCCTTGAAGCTG
CAAAAAATGCTGACCGAAAACCACATCAGTAAATACAACGTCGGCAGCTCAGACTTCACCGCCCCGTCAACCGACAAAAC
CGTGATCCTCGTTCCCGGCCAGGTTGAAGATGATGCGTCTATCCGCTACGGTTCGCCCCAAATCTACCGCAATCTGGATT
TGCTCCGTACCGTACGCGAACGAAACCCCAATGCCTATATCATCTACAAACCGCATCCCGATGTAGTCAGCGGTAACCGC
ATCGGCCATATTTCCCCTGAAGATGCTGCACGATATGCCGACCAAACCGCCGAGCAAACCGACATCCTGACCTGTCTCCA
ATACGCAGACGAAGTACATACCATGACTTCGCTGACCGGTTTTGAAGCCTTGTTGCGCGGCAAAAAAGTCAGCTGCTACG
GCCTGCCTTTTTACGCAGGCTGGGGACTTACCCAAGATCTGCTCCCCATTCCGCGCCGTAGCCGCAGACTTGAGCTTTGG
CAGCTGATTGCCGGCACGCTCATCCACTATCCCGACTACATCCACCCCGAAACCCATCAGGCCATAAATGCAGAAACCGC
AGCCCAAATCCTGATACGACAAAAAAATATGCAAAAAAACAACAACGGATTACATCGCGGGTACTTTGCCAAAAAATTAG
GTAAAATCAAACAACTATATCGATCTTTCAAATAA

Protein sequence :
MFLFSDGLQSINNNNRRKRIVKNAYIPSRGIRKIPHLSTLLPEFHIYKDGKGAEAVVGWGLRPTTHKARAFATEHQLPFI
ALEDGFLRSLGLGVSGYPPYSIVYDDIGIYYDTTRPSRLEQLILAADTMPSETLAQARQAMDFILQHHLSKYNHAPELSD
DHPLRSPSKSETVLIIDQTFGDMAIQYGGADASTFELMFQTALNENPQADIWVKTHPDVLCGKKQGYLTQLVQQHRVHLL
AEDINPISLLQNVDKVYCVTSQMGFEALLCGKPLTTFGLPWYAGWGVSDDRHPKIGSLIQTQRRAPRNLLQLFAAAYLQY
SRYLNPNTGEAGSLFDVIDYLATVKRKNDKLRGELYCVGMSLWKRAVAKPFFNVPSCRLKFISSTQKLARVKLSDDARIL
AWGNGKEAIVRFAEQHHIPLLRMEDGFIRSVGLGSNLVPPLSLVTDDMSIYFNAETPSRLEYILQNQNFDDQDFQTALKL
QKMLTENHISKYNVGSSDFTAPSTDKTVILVPGQVEDDASIRYGSPQIYRNLDLLRTVRERNPNAYIIYKPHPDVVSGNR
IGHISPEDAARYADQTAEQTDILTCLQYADEVHTMTSLTGFEALLRGKKVSCYGLPFYAGWGLTQDLLPIPRRSRRLELW
QLIAGTLIHYPDYIHPETHQAINAETAAQILIRQKNMQKNNNGLHRGYFAKKLGKIKQLYRSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 98
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 7e-134 49
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 5e-134 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lipA YP_001598266.1 capsule polysaccharide modification protein VFG0259 Protein 0.0 98
lipA YP_001598266.1 capsule polysaccharide modification protein VFG0704 Protein 5e-157 58
lipA YP_001598266.1 capsule polysaccharide modification protein VFG0692 Protein 3e-180 58