Gene Information

Name : kdsB (NMCC_0629)
Accession : YP_001598780.1
Strain : Neisseria meningitidis 053442
Genome accession: NC_010120
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 644954 - 645715 bp
Length : 762 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGACCGAATTCGTCGTATTGATTCCGGCGCGGCTGGATTCGTCGCGCCTGCCCGGAAAAGCCTTGGCGGACATCCACGG
CAAACCGATGGTCGTGCGCGTTGCCGAACAGGCGGCAAAAAGTAAAGCCGCGCGCGTCGTCGTCGCCACCGACCATCCCG
ATATTCAGACGGTCTGTCAGGCGCACGGCATCGAAGCGGTTATGACTTCAAACCGGCACGAAAGCGGCACGACGCGCCTT
GCCGAAGCCTCTGCCGCGCTGAAGCTGCCGCCGCATTTGATTGTTGTGAACGTACAGGGTGACGAGCCGCTGATTGCCCC
CGAACTCATCGACCGCACCGCCGAAGTACTCGTCGAAAACAACGTCCAAATGGCGACCGCCGCCCACGAATTGCACGATT
TCGACGAATTGATGAATCCCAATGCCGTCAAAGTCGTCCTCGACAAAAACCGCAACGCCATCTACTTCAGCCGCGCCCCG
ATTCCCTATCTGCGCGATGCAATGCGTGCCGGAAAACGCGAAATGCCGTCTGAAACCGCCGTCCTGCGACATATCGGCAT
CTACGCTTACCGCGCCGGCTTCCTGCAACGCTATGCCGAAATGAGCGTTTCGCCGCTGGAAACCATCGAATCGCTGGAAC
AGCTGCGCGTCCTGTGGCACGGTTATCCCATTGCCGTCGAAACCGCCAAAGAAGCCCCCGCCGCCGGTGTGGATACGCAA
GAGGACTTGGACAGGGTTCGCGCCGTATTTCAGACCGTATAA

Protein sequence : 
MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTVCQAHGIEAVMTSNRHESGTTRL
AEASAALKLPPHLIVVNVQGDEPLIAPELIDRTAEVLVENNVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAP
IPYLRDAMRAGKREMPSETAVLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQ
EDLDRVRAVFQTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-30 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-30 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-30 43