Gene Information

Name : hemC (NMCC_0478)
Accession : YP_001598634.1
Strain : Neisseria meningitidis 053442
Genome accession: NC_010120
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 497279 - 498229 bp
Length : 951 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAACGCATTGAACATGAACCCGAAAAAACTCGTCATCGCCAGCCGCGAAAGCCTGCTTGCTATGTGGCAGGCAAAGCA
TATCCAAGGCCGTCTGAAGGCTCTGTATCCCGATTGCGAAGTCGAGATTTTGGGCATGACCACGCGCGGCGATCAGATTT
TGGACAAAACTTTGTCAAAAGTCGGCGGTAAAGGCTTGTTTGTCAAAGAGTTGGAACAGGCTTTATATGACGGGCGCGCC
GATTTGGCGGTGCATTCGATTAAAGACGTACCGATGGATTTGCCTGAAGGTTTCGCGCTTGCGACCATCGGCGAACGCGC
CAATCCGTTTGACGCATTTGTGTCCAACCAATACACGCGTTTGGAAGAAATGCCCGAAGGCGCGGTTGTCGGCACATCCA
GCCTGCGCCGCGAAGCCCAGTTGCGTGCGCGCTATCCGCATTTGCTTATCAAACCTTTGCGCGGCAATGTGCAAACCCGT
TTGTCCAAACTCGATAACGGCGAATACGACGCAATTATCTTGGCTGCCGCCGGTTTGCAGCGTCTGAAATTGGACGGACG
CATCCGCATGATTTTGTCGGAATCCGACAGCCTGCCTGCCGCCGGACAAGGCGCATTGGGTATCGAAATTGCCGCGCACC
GCGAAGATTTGTATGAAGTTTTGAAACCCTTGAACCACGGCGTTACCAATGCCTGCGTTACCGCCGAACGCGCCCTCGCA
CGCGCTTTGGGCGGAAGCTGCCAAGTGCCTTTGGCCGCATATTGCACGGAAGAAAACGGCTTGCTGACCTTGCGCGGCTT
GGTCGGACACCCCGACGGTTCGGTTGTGTTGCGGGCGGACGCGCAAGCCCCTGCCGAATATGCCGACGCGCTCGGACGCG
CAGTCGCTAAGAAATTGGCGGACGACGGTGCGCAGGAATTGATTGGGGCGGTATTGAATACGGAAAATTGA

Protein sequence :
MNALNMNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKGLFVKELEQALYDGRA
DLAVHSIKDVPMDLPEGFALATIGERANPFDAFVSNQYTRLEEMPEGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTR
LSKLDNGEYDAIILAAAGLQRLKLDGRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALA
RALGGSCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGAQELIGAVLNTEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-70 56
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-70 56