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Name : leuS (NMCC_0323) Accession : YP_001598485.1 Strain : Neisseria meningitidis 053442 Genome accession: NC_010120 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 328478 - 331222 bp Length : 2745 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : TTGCCGTGTCGCCCGCCTCCTGCCGGCAATCTGCCGATTCGCCGCTTCCGGCAACCTGTTATAATTGATGCCGACTTTAT TTTTCCAACGTTTTTAAGCGAAAACAGAATGACTATGCAAGAACAATACCGGCCCGCCGCCATCGAGCCTGCGGCGCAGA AAAAATGGGATGATGCCCGTATTTTCAACGTCTCCGAAGACGCTTCCAAACCCAAATACTACTGCCTCTCTATGTTCCCC TATCCCAGCGGCAAGCTGCATATGGGGCATGTGCGCAACTACACCATTGGCGACGTATTGAGCCGCTTCAAACGCTTAAA CGGCTTCAACGTCATGCAGCCTATGGGTTGGGACGCGTTCGGCATGCCGGCGGAAAACGCGGCGATGAAAAACAACGTCG CCCCCGCCGCATGGACTTACGACAACATCGAATACATGAAAACCCAGCTCAAAAGCCTGGGTTTTGCGATTGACTGGGCG CGCGAAACCGCCACCTGCAAACCCGAATACTACCGCTGGGAACAATGGCTGTTTACCAAGCTGTTTGAAAAAGGCATCGT TTACCGCAAAAACGGCACGGTAAACTGGGACCCTGTCGATCAAACCGTCCTTGCCAACGAGCAAGTTATCGACGGGCGCG GCTGGCGTTCGGGCGCGTTGATTGAAAAACGCGAAATCCCGATGTATTACTTCAAAATCACCGATTACGCCGAAGAGTTG CTCAACGATTTGGACAAGCTGGAACACTGGCCGGAACAAGTCAAAACCATGCAGCGCAACTGGATCGGCAAATCTCGCGG TATGACCGTGCGCTTTGCCGTTTCAGACGACAGCAAACAAGGTTTGGAAGGCGATTACGCGAGATTCCTGCAAGTTTATA CCACCCGCCCCGACACGCTGATGGGCGCGACTTATGTTGCCGTTGCCGCCGAGCATCCGCTGGCAACCGCAGCCGCCGCC GACAAACCCGAATTGCAGGCATTTATCGCCGAATGCAAAGCGGGCTCCGTTGCCGAAGCCGATATGGCGACGATGGAGAA AAAAGGCGTGCCGACCGGTCGCTACGTCGTCAACCCGCTCAACGGCGATAAGCTGGAAGTGTGGATTGCCAACTATGTAT TGTGGGGCTACGGCGACGGCGCGGTGATGGCGGTTCCGGCGCACGACGAACGCGATTTCGAGTTTGCCACCAAATACAGC CTGCCGAAAAAACAGGTCATTGCCGTCGGCGACAACGCATTTGACGCAAACCAATGGCAAGAATGGTACGGCGACAAAGA AAACGGCGTATTGGTCAACAGCGGCGACTTGGACGGCATGAATTTTCAGACGGCCTTCGACGCCATCGCCGCCAAGCTGC AAAGCCAAGGCGCGGGCGAACCGAAAACCCAATACCGCCTGCGCGACTGGGGCATTTCGCGCCAACGCTACTGGGGCTGC CCGATTCCCATCGTCCATTGCGAACAATGCGGCGACGTACCCGTCCCTGCCGACCAACTGCCCGTCGTCCTGCCTGAAAA CGTCGTACCCGACGGTATGGGTTCGCCGCTGGCAAAAATGCCCGAGTTTTACGAAACTGCCTGCCCGTGCTGCGGCGGCG CGGCGAAACGCGAAACCGACACCATGGACACCTTCATGGAATCAAGCTGGTATTTCTTCCGCTACATGTCGCCCAAGTTT TCAGACGGCATGGTATCGGCGGAAGCCGCAAAATACTGGGGCGCGGTCGACCAATACATCGGCGGTATCGAACACGCGAT TCTGCACCTCTTGTACGCGCGTTTCTTCACCAAACTGATGCGCGACGAAGGTTTGGTCAATGTTGACGAACCGTTTGAAC GCCTGCTGACGCAAGGCATGGTCGTTTGCGAAACCTACTACCGTGAAAACGACAAAGGCGGCAAAGACTGGATCAACCCT GCCGATGTCGAGCTGACTTTCGACGATAAAGGCCGCCCTGTTTCCGCCGTTCTGAAAGCAGACGGACTGCCAGTCGTCAT CAGCGGCACGGAAAAAATGTCCAAGTCCAAAAACAACGGCGTCGATCCGCAAGAGCTGATTAACGCCTACGGCGCGGACA CCGCCCGCCTGTTCATGATGTTCGCCGCACCGCCCGAACAGTCCCTCGAATGGAGCGACAGCGGCGTCGAAGGCGCACAC CGCTTCCTGCGCCGCCTGTGGCGTACCGTTTACGAATACCTGAAACAAGGCGGCGCGGTCAAAGCGTTTGCAGGCAACCA AGACGGTTTGTCTAAAGAACTCAAAGATCTGCGCCACAAACTGCATTCCACCATCGCCAAAGTCAGCGACGACTACGGCC GCCGCCAGCAGTTCAACACCGCCATCGCCGCCGTGATGGAATTGCTCAACCAATACGACAAAACCGACACCGGCAGCGAA CAAGGCCGCGCCGTCGCCCAAGAAGTATTGGAAACCGCCGTACGCCTGCTGTGGCCCATCGTGCCGCACATCTGCGAAAC CCTGTGGAGCGAATTGAACGGCGCGAAACTGTGGGAAGCAGGCTGGCCGGCAGTCGACGAAGCCGCCTTGGTCAAATCCG AAATCGAAGTCATGGTTCAAGTCAACGGCAAACTGCGCGGCAAAATCACCGTCGCCGCCGACGCATCCAAGGCCGACCTC GAAGCCGCCGCCCTTGCCACCGAAGGCGCGGTGAAATTCATGGAAGGCAAGCCCGCGAAGAAAATCATCGTCGTTCCCGG ACGCTTGGTAAATATCGTCGTCTAA Protein sequence : MPCRPPPAGNLPIRRFRQPVIIDADFIFPTFLSENRMTMQEQYRPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFP YPSGKLHMGHVRNYTIGDVLSRFKRLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWA RETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAEEL LNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQGLEGDYARFLQVYTTRPDTLMGATYVAVAAEHPLATAAAA DKPELQAFIAECKAGSVAEADMATMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFATKYS LPKKQVIAVGDNAFDANQWQEWYGDKENGVLVNSGDLDGMNFQTAFDAIAAKLQSQGAGEPKTQYRLRDWGISRQRYWGC PIPIVHCEQCGDVPVPADQLPVVLPENVVPDGMGSPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKF SDGMVSAEAAKYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYRENDKGGKDWINP ADVELTFDDKGRPVSAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAYGADTARLFMMFAAPPEQSLEWSDSGVEGAH RFLRRLWRTVYEYLKQGGAVKAFAGNQDGLSKELKDLRHKLHSTIAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGSE QGRAVAQEVLETAVRLLWPIVPHICETLWSELNGAKLWEAGWPAVDEAALVKSEIEVMVQVNGKLRGKITVAADASKADL EAAALATEGAVKFMEGKPAKKIIVVPGRLVNIVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 7e-139 | 41 |
