Gene Information

Name : mutS (NMCC_2120)
Accession : YP_001600204.1
Strain : Neisseria meningitidis 053442
Genome accession: NC_010120
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 2150705 - 2153299 bp
Length : 2595 bp
Strand : +
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
ATGTCCAAATCCGCCGTTTCCCCAATGATGCAGCAATACCTCGGCATCAAAGCGCAACATACCGACAAACTGGTGTTTTA
CCGTATGGGCGATTTTTACGAGATGTTTTTCGACGATGCGGTAGAAGCGGCAAAACTTTTGGATATTACCCTGACCACGC
GCGGGCAGATGGACGGCGTGCCGATTAAAATGGCAGGCGTGCCGTTTCACGCCGCCGAACAATATCTGGCGCGCCTGGTC
AAGTTGGGCAAAAGCGTGGCGATTTGCGAACAGGTCGGCGAAGTCGGCGCGGGCAAAGGGCCAGTAGAACGCAAAGTCGT
GCGCATCGTAACGCCTGGCACGCTAACCGATTCCGCATTGCTGGAAGACAAGGAAACCAACCGCATCGTTGCCGTGTCCC
CCGACAAAAAATACATCGGTTTGGCGTGGGCATCGCTGCAAAGCGGCGAATTCAAAACCAAGCTGACAACTGTGGATAAA
TTGGACGACGAACTGGCGCGCCTGCAGGCGGCGGAAATTCTGTTGCCGGACAGTAAAAACACACCGCAACTTCAGACGGC
ATCGGGTGTTACGCGCCTGAACGCGTGGCAGTTTGCCGCCGACGCGGGGGAAAAACTGCTGACGGAATATTTCGGCTGCC
AAGATTTACGCGGCTTCGGGTTGGACGGCAAAGAACACGCCGTTGCGATTGGCGCGGCAGGTGCGCTGTTGAACTATATC
CGCCTGACGCAAAACCTGATGCCGCAACATTTGGACGGCCTGTCGCTCGAAACCGACAGCCAATATATCGGCATGGACGC
CGCCACGCGCCGCAATCTCGAAATCACGCAAACCCTCTCCGGCAAAAAATCGCCGACCCTGATGTCCACGCTCGACCTTT
GCGCCACCCACATGGGCAGCCGCCTCTTGGCTCTCTGGCTGCACCACCCTTTGCGCAACCGCGCCCACATCCGAGCACGC
CAAGAAGCCGTTGCCGCGCTGGAAAGCCAATACAAACCCCTCCAATGCCGTCTGAAAAACATTGCGGACATTGAACGCAT
TGCCGCCCGCATCGCCGTCGGCAACGCACGTCCGCGCGACCTCGCCGCCCTGCGCGACAGCCTGTTTGCCCTGTCAGAAA
TCGACTTGTCCGCAAACGGCAGCAGCCTGTTGGAAACCCTCAAAGCCGTTTTCCCGGAAACCCTGCCAGTTGCCGAAACC
CTCAAAGCCGCCGTGATGCCCGAACCTGCCGTCTGGCTGAAAGACGGCAATGTCATCAATCACGGTTTTCATCCCGAACT
GGACGAATTGCGCCGCATTCAAAACCATGGCGACGAATTTTTGCTGGATTTGGAAGCCAAGGAACGCGAACGTACCGGTT
TGTCCACACTCAAAGTCGAGTTCAACCGTGTTCACGGCTTTTACATTGAATTGTCCAAAACCCAAGCCGAACAAGCACCT
GCCGACTACCAACGCCGGCAAACCCTTAAAAACGCCGAACGCTTCATCACGCCGGAACTGAAAGCCTTTGAAGACAAAGT
GATGACTGCTCAAGAGCAAGCCCTCGCCTTAGAAAAACAACTCTTTGACGGCGTATTGAAAAACCTTCAGACGGCATTGC
CGCAGCTTCAAAAAGCCGCCAAAGCCGCCGCCGCGCTGGACGTGTTGTCCACATTTTCAGCCTTGGCAAAAGAGCGGAAC
TTCGTCCGCCCCGAGTTTGCCGACTATCCGGTTATCCACATCGAAAACGGTCGCCATCCCGTTGTCGAACAGCAGGTACG
CCACTTCACCGCCAACCACACCAACCTTGACCACAAACACCGCCTCATGCTGCTCACCGGCCCCAATATGGGCGGCAAAT
CCACCTATATGCGCCAAGTCGCGCTGATTGTTTTATTGGCACACACCGGCTGTTTCGTGCCTGCCGATGCCGCCACAATC
GGACCTATCGATCAAATCTTCACCCGCATCGGCGCATCGGACGATCTCGCCTCCAACCGCTCCACCTTCATGGTCGAAAT
GAGCGAAACCGCCTACATCCTGCATCACGCCACCGAACAAAGCCTTGTTTTAATGGACGAGGTCGGACGTGGTACTTCCA
CTTTCGACGGCCTTGCCCTCGCGCACGCCGTTGCTGAACACCTGCTGCAAAAAAACAAATCCTTCAGCCTGTTTGCCACC
CACTATTTCGAGCTGACCAAACTGCCTGAAGCCCATGCAACCGCAGTCAATATGCACCTCTCCGCGCTTGAGCAAGGACA
GGACATCGTCTTCCTCCACCACATCGAACCGGGTCCTGCAAGCAAAAGCTACGGCATCGCCGTCGCCAAACTCGCCGGTC
TGCCTGTACGCGCATTGAAATCCGCCCAAAAGCATTTGAACGAACTGGAAGACCAAGCCGCCGCAAACCGTCCACAACTG
GATATTTTCAGTACCATGCCGTCTGAAAAAGGAGATGAACCGAATGTGGACAGCTTTGTGGACAAAGCAGAGGAAAAACA
TTTTGAAGGTATATTGGCAGCAGCCCTGGAGAAACTCGATCCCGACAGCCTGACCCCGCGCGAAGCATTGTCAGAACTGT
ACCGTCTGAAAGATTTGTGCAAATCCGTATCTTAA

Protein sequence :
MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYEMFFDDAVEAAKLLDITLTTRGQMDGVPIKMAGVPFHAAEQYLARLV
KLGKSVAICEQVGEVGAGKGPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTVDK
LDDELARLQAAEILLPDSKNTPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDGKEHAVAIGAAGALLNYI
RLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKSPTLMSTLDLCATHMGSRLLALWLHHPLRNRAHIRAR
QEAVAALESQYKPLQCRLKNIADIERIAARIAVGNARPRDLAALRDSLFALSEIDLSANGSSLLETLKAVFPETLPVAET
LKAAVMPEPAVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAP
ADYQRRQTLKNAERFITPELKAFEDKVMTAQEQALALEKQLFDGVLKNLQTALPQLQKAAKAAAALDVLSTFSALAKERN
FVRPEFADYPVIHIENGRHPVVEQQVRHFTANHTNLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATI
GPIDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQSLVLMDEVGRGTSTFDGLALAHAVAEHLLQKNKSFSLFAT
HYFELTKLPEAHATAVNMHLSALEQGQDIVFLHHIEPGPASKSYGIAVAKLAGLPVRALKSAQKHLNELEDQAAANRPQL
DIFSTMPSEKGDEPNVDSFVDKAEEKHFEGILAAALEKLDPDSLTPREALSELYRLKDLCKSVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 9e-169 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mutS YP_001600204.1 DNA mismatch repair protein MutS VFG0562 Protein 1e-178 50