Gene Information

Name : murD (NMCC_1724)
Accession : YP_001599827.1
Strain : Neisseria meningitidis 053442
Genome accession: NC_010120
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 1768668 - 1770005 bp
Length : 1338 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGACTTTCCAAAACAAAAAAATCCTCGTCGCCGGACTTGGCGGCACGGGTATTTCCATGATTGCCTACCTGCGCAAAAA
CGGCGTGGAGGTTGCCGCTTATGATGCGGAGTTGAAGCCCGAGCGCGTGGCGCAAATCGGTAAGATGTTTGACGGGCTGG
TGTTTTACACAGGCCGTCTGAAAGATGCGCTGGACAACGGTTTTGATATTCTGGCGCTCAGCCCCGGCATCAGCGAGCGG
CAGCCGGATATCGAGGCGTTCAAGCAAAACGGCGGGCGCGTGTTGGGTGATATCGAATTGCTGGCGGATATTGTGAACCG
CCGAGGCGACAAGGTGATTGCGATTACCGGCAGCAACGGCAAAACCACGGTAACGAGCCTGGTCGGCTATCTCTGCATCA
AGTGCGGGCTGGATACCGTTATCGCGGGCAATATCGGCACGCCGGTTTTGGAGGCGGAATGGCAGCGCGAAGGCAAAAAG
GCGGACGTGTGGGTGTTGGAGCTTTCCAGCTTCCAACTGGAAAACACCGAAAGCCTGCGCCCGACTGCGGCGACGGTGCT
GAACATTTCCGAAGACCATCTCGACCGCTACGACGACTTGCTCGACTATGCGCATACCAAGGATAAGATTTTCCGTGGCG
ATGGCGTGCAGGTTTTGAATGCGGACGATGCGTTCTGTCGTGCGATGAAGCGCGCCGGGCGCGAGGTGAAATGGTTTTCG
TTGGAATACGAAGCCGATTTTTGGTTGGAACGTGAGACAGGTCGCCTGAAACAAGGCAATGAAGATTTGATTGCCACGCA
AGATATTCCGCTGCAAGGCTTGCACAACGCCACTAACGTGATGGCTGCCGTTGCCTTGTGCGAAGCCGTCGGTTTGCCGC
GCGAAGCATTGCTCGAACACGTCAAAACCTTTCAAGGCCTGCCGCACCGCGTGGAAAAAATCGGCGAGAAAAATGGCGTG
GTGTTCATCGACGACAGCAAAGGCACGAACGTCGGCGCGACAGCCGCCGCGATTGCCGGTTTGCAAAATCCGCTATTCGT
CATTTTGGGCGGCATGGGCAAAGGGCAGGACTTCACGCCCCTGCGCGACGCGCTTGCCGGCAAGGCAAAAGGCGTGTTCC
TGATTGGTGTCGATGCGCTGCAAATCCGCCGCGATTTGGACGGCTGCGATCTGAATATGACCGACTGCGCCACTTTGGAA
GAAGCGGTTCAGAAGGCATATGCCCAAGCCGAAGCGGGCGATATCGTGCTGCTCAGCCCCGCCTGCGCGAGCTTCGATAT
GTTTAAAGGCTATGCGCACCGTTCGGAAGTGTTTATCGGGGCGTTTAAGGCTTTGTGA

Protein sequence :
MTFQNKKILVAGLGGTGISMIAYLRKNGVEVAAYDAELKPERVAQIGKMFDGLVFYTGRLKDALDNGFDILALSPGISER
QPDIEAFKQNGGRVLGDIELLADIVNRRGDKVIAITGSNGKTTVTSLVGYLCIKCGLDTVIAGNIGTPVLEAEWQREGKK
ADVWVLELSSFQLENTESLRPTAATVLNISEDHLDRYDDLLDYAHTKDKIFRGDGVQVLNADDAFCRAMKRAGREVKWFS
LEYEADFWLERETGRLKQGNEDLIATQDIPLQGLHNATNVMAAVALCEAVGLPREALLEHVKTFQGLPHRVEKIGEKNGV
VFIDDSKGTNVGATAAAIAGLQNPLFVILGGMGKGQDFTPLRDALAGKAKGVFLIGVDALQIRRDLDGCDLNMTDCATLE
EAVQKAYAQAEAGDIVLLSPACASFDMFKGYAHRSEVFIGAFKAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 4e-57 42
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 4e-57 42