Gene Information

Name : pykA (NMCC_0098)
Accession : YP_001598274.1
Strain : Neisseria meningitidis 053442
Genome accession: NC_010120
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 98175 - 99647 bp
Length : 1473 bp
Strand : -
Note : Code: G; COG: COG0469

DNA sequence :
ATGAACCAGACAAGCCGCGATCTGACCCGCATCAGCCACAACACCAAAATCGTCGCCACCCTTGGGCCGGGCAGCAACAA
CGTAGAACTGTTGGAAGATATGATCCGCGTCGGCGGCCTGAACGTCGTCCGCTTCAACTTCAGCCACGGCACGCCCGAAT
TCCATCAGGAAAACGCCCGCATCGTGCGCGAGGCGGCAAAACGCGCCGGACAGGAAATCGCCATCATTGCCGACCTGCAA
GGGCCGAAAATCCGCGTGGGCAAAATCGCCGGCGGCGGCATTGAATTGAACAAAGGCGAAACGCTGGTACTGGATGCCGC
GCTCGAAGGCGAAGGCACGCGCGAGGCGGTCGGTTTGGACTACCGCGACCTGCCCGACGACGTTGCCGCAGGCGACGTAT
TGTGGCTGGACGACGGCCTGCTGACCCTGACCGTGGAATCCGTCGAAGGCAGCAGGATTATCACAAGGGTGGAAAACAGC
CACGTCCTGAAAAGCAACAAGGGCATCAACAAACGCGGCGGCGGTCTGTCCGCAGGCGCGTTGACCGAAAAAGACTTCCG
CGACCTGAAAACCGCGATTGCCATCGGTTGCGACTACCTCGCCATCAGCTTTGTGAAATCCGCCGAAGATTTGCATATCG
CGCGCGCCAAAGTCGAAGAAGAAATGAAGGGCAGCACGGCCGTGCGCCCCGGTTTGGTTTCCAAAATCGAACGCGTGGAA
GCGATTGAAAACTTGGACGAAATCATCCTTGCCGGCGACGGCATTATGGTTGCGCGCGGCGACTTGGCGGTCGAAGTCGG
ACACGCCGCCGTCCCCGCCCTGCAAAAACGGATGATCCGCCGCGCCCGCGAGTTGCGCCGCTTCAGCATTACGGCGACGC
AAATGATGGAATCGATGATTACCAACCCCGTGCCGACCCGCGCGGAAGTCAGCGATGTGGCAAACGCGGTATTGGACGGC
ACCGATGCGGTGATGTGTTCCGCCGAAACCGCCGTCGGCGCGTATCCGTTTGAAACCGTCAGCCAAATGGCAATTATCTG
CGCGGCTGCGGAAAAAGAGCAGGATTCGCTCAACGGCGTTGCCGAACAGGCGGAGTATCCCGAAGCGGTCAGCACCAACC
TGGCGGTTGCCGGCGGCGCGGTCAGCGTGGCGCGCGCGGTTCACGCCAAAGCCATCGTCGCCCTGACCGAAAGCGGTTCG
ACCGCCTTTGAAATCAGCCGCCACAACATCACCCTGCCGATTTTCGCGCTGACCCCGAGCGTTTCCGCCCAACGCCGTAT
GGCGATGTACCGGGGCGTGCGCCCGCTGATTTTGGCAACCAGCACCGACCACGACACGGCGTTAAACGAAGTCGAAACCA
TGCTGGTGGAACACAACATCCTGCATTCCGGCGACCAATACATCATTACCAGCGGCTCGCAAATGCGCGAATCCGGTTCG
ACCAATACGCTGGAAGTGCTGCGCGTCAAATAA

Protein sequence :
MNQTSRDLTRISHNTKIVATLGPGSNNVELLEDMIRVGGLNVVRFNFSHGTPEFHQENARIVREAAKRAGQEIAIIADLQ
GPKIRVGKIAGGGIELNKGETLVLDAALEGEGTREAVGLDYRDLPDDVAAGDVLWLDDGLLTLTVESVEGSRIITRVENS
HVLKSNKGINKRGGGLSAGALTEKDFRDLKTAIAIGCDYLAISFVKSAEDLHIARAKVEEEMKGSTAVRPGLVSKIERVE
AIENLDEIILAGDGIMVARGDLAVEVGHAAVPALQKRMIRRARELRRFSITATQMMESMITNPVPTRAEVSDVANAVLDG
TDAVMCSAETAVGAYPFETVSQMAIICAAAEKEQDSLNGVAEQAEYPEAVSTNLAVAGGAVSVARAVHAKAIVALTESGS
TAFEISRHNITLPIFALTPSVSAQRRMAMYRGVRPLILATSTDHDTALNEVETMLVEHNILHSGDQYIITSGSQMRESGS
TNTLEVLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 0.0 99
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-53 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-53 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-53 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_001598274.1 pyruvate kinase VFG0479 Protein 1e-53 42