Gene Information

Name : lpdA3 (NMCC_0900)
Accession : YP_001599038.1
Strain : Neisseria meningitidis 053442
Genome accession: NC_010120
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 902523 - 903956 bp
Length : 1434 bp
Strand : +
Note : E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGTCTCAATATGATGTAGTAGTGATTGGTGCAGGCCCGGGCGGATACGTTGCCGCCATCCGTGCCGCACAACTGGGTTT
CAAAACTGCCTGTGTCGATGCAGGCGTTAACAAAGCAGGCAATGCCCCTGCATTGGGCGGTACTTGCTTGAACGTAGGCT
GTATCCCTTCTAAAGCCCTGTTGCAATCCAGCGAACATTTCCACGCTGCGCAACACGATTTTGCCGAACACGGTATCACT
GTCGGCGACGTAAAATTCGACGCGGCCAAAATGATTGAGCGCAAAGATGCCATCGTGACCAAACTGACCGGCGGCGTGAA
ATTCCTGTTCCAAAAAAACAAAGTAACCAGCCTGTTCGGTACTGCTTCCTTTGCCGGTAAAAATGGCGATGCTTACCAAA
TCGAAGTCGATAACAAAGGCGAGAAAACCGTTATCGAAGCCAAACACGTCATCGTAGCGACCGGTTCCGTACCGCGTCCG
CTGCCACAAGTCGCTATCGACAACGTTAACGTATTGGACAACGAAGGCGCATTGAACCTGACCGAAGTACCTGCCAAACT
CGGCGTGATCGGTTCCGGCGTGATTGGTTTGGAAATGGGTTCCGTATGGAACCGCGTGGGTTCAGAAGTTACCATTCTTG
AAGCCGCACCGACTTTCTTGGCTGCCGCCGACCAACAAATCGCCAAAGAAGCCTTCAAATACTTCACCAAAGAGCAAGGT
CTGAGCATCGAATTGGGCGTGAAAATCGGCGACATCAAATCTGAAGGCAAAGGTGTTTCCGTTGCTTACGAAACTGCTGC
CGGCGAAGCCAAAACCGAAGTATTCGACAAACTGATCGTTGCCATCGGCCGTATTCCAAACACCAAAGGCCTGAACGCGG
AAGCCGTAGGCTTGGAAAAAGACGAGCGCGGCTTTATCAAAGTAGATGGCGAATGCCGTACCAACCTGCCTAACGTATGG
GCAATCGGCGACGTGGTTCGCGGCCCGATGTTGGCACACAAAGCCAGCGACGAAGGCGTTGCCGTTGCCGAACGCATTGC
CGGTCAAAAACCGCATATCGACTTCAACAACGTACCGTTCGTGATTTACACCGATCCTGAAATCGCTTGGGTGGGTAAAA
CCGAAGAGCAGCTCAAAGCCGAAGGCGTGGAGTACAAAAAAGGTACTTCAGGTTTTGGTGCGAATGGTCGCGCATTGGCA
ATGGGCAAAGCCAAAGGTACGGTTAAAGTGTTGGCAGACGCCAAAACCGACCGCATCTTGGGCGTACACATGATTGGTCC
GGTTGTCAGCGAATTGGTTACCGAAGGCGTGACTGCGCTCGAATTCTTCGCCAGCAGCGAAGACATCGCCCGCATTATCC
ATGCCCACCCAACCTTGTCCGAAGTGGTTCACGAAGCTGCATTGGCGGCCGACAAACGCGCTTTGCACGGTTGA

Protein sequence :
MSQYDVVVIGAGPGGYVAAIRAAQLGFKTACVDAGVNKAGNAPALGGTCLNVGCIPSKALLQSSEHFHAAQHDFAEHGIT
VGDVKFDAAKMIERKDAIVTKLTGGVKFLFQKNKVTSLFGTASFAGKNGDAYQIEVDNKGEKTVIEAKHVIVATGSVPRP
LPQVAIDNVNVLDNEGALNLTEVPAKLGVIGSGVIGLEMGSVWNRVGSEVTILEAAPTFLAAADQQIAKEAFKYFTKEQG
LSIELGVKIGDIKSEGKGVSVAYETAAGEAKTEVFDKLIVAIGRIPNTKGLNAEAVGLEKDERGFIKVDGECRTNLPNVW
AIGDVVRGPMLAHKASDEGVAVAERIAGQKPHIDFNNVPFVIYTDPEIAWVGKTEEQLKAEGVEYKKGTSGFGANGRALA
MGKAKGTVKVLADAKTDRILGVHMIGPVVSELVTEGVTALEFFASSEDIARIIHAHPTLSEVVHEAALAADKRALHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 1e-66 42