Gene Information

Name : folA (COXBURSA331_A0096)
Accession : YP_001595986.1
Strain : Coxiella burnetii RSA 331
Genome accession: NC_010117
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 86223 - 86708 bp
Length : 486 bp
Strand : +
Note : identified by match to protein family HMM PF00186

DNA sequence :
ATGATTATTACTCTAATTGCCGCGATGGATAAAAATCGACTGATTGGCCGAAATAACGAGCTGCCGTGGCATTTGCCTGC
TGATTTAGCCCATTTTAAATCGATTACGCTCGGCAAGCCGATTGTGATGGGCCGACGGACGTTTGACAGCATTGGGAAAC
CTTTGCCTCACCGCCGAAATATTGTCATTACGCAGCAAAAAAATTTAATTATTGAAGGTTGTGATATTTTCTATTCTTTG
GATGACGCACTGAGCGCATTGACCAAGGAGCCCGAAGTAATAATCATCGGCGGCGCTCGCATTTTCAAAGAGGCGTTGCC
GAAGGCCGATAAAATGATCTTGACTATCATCAATCACTCTTTTGAAGGTGATGTTTATTTTCCTGAATGGAATGATAAAG
AATGGAAAATTACCTCACAAATTAAACACGAACGGGACGAAAAAAATCCTTATCCTTTTCAGTTTTTAGAATTAAGGCGA
TTATAG

Protein sequence :
MIITLIAAMDKNRLIGRNNELPWHLPADLAHFKSITLGKPIVMGRRTFDSIGKPLPHRRNIVITQQKNLIIEGCDIFYSL
DDALSALTKEPEVIIIGGARIFKEALPKADKMILTIINHSFEGDVYFPEWNDKEWKITSQIKHERDEKNPYPFQFLELRR
L

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
folA-2 YP_189146.1 dihydrofolate reductase Not tested ¥ÕSP¥â Protein 7e-30 44
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 3e-25 44