Gene Information

Name : kdsB (COXBURSA331_A0589)
Accession : YP_001596409.1
Strain : Coxiella burnetii RSA 331
Genome accession: NC_010117
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 497055 - 497804 bp
Length : 750 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGGAATTCCGAGTTATTATTCCCGCGCGTTTTGATTCCACTCGTTTACCCGGCAAAGCATTAGTTGACATTGCCGGCAA
ACCGATGATTCAGCACGTTTATGAAAGTGCGATTAAAAGCGGTGCTGAAGAGGTTGTGATTGCTACCGACGATAAAAGAA
TCCGCCAAGTCGCCGAAGATTTTGGCGCAGTGGTTTGCATGACTTCTTCCGATCATCAATCGGGTACTGAACGTATTGCC
GAGGCTGCGGTTGCGTTAGGTTTTGAAGATGATGAGATTATCGTTTGTTTGCAAGGCGATGAACCTCTAATTCCACCGGA
TGCCATTCGTAAATTAGCGGAAGACTTGGATGAACATGATAATGTTAAAGTTGCTTCTCTTTGTACGCCCATTACAGAGG
TCGATGAGTTATTTAATCCGCACAGTACTAAAGTCGTTTTAAACCGGCGCAATTACGCGCTTTATTTTAGTCACGCTCCC
ATTCCGTGGGGCCGTGATACTTTTTCTGATAAAGAGAACCTCCAATTGAATGGTTCTCATTACTGCCATGTCGGTATCTA
TGCTTACCGAGTGGGTTTTCTAGAAGAATATCTTTCCTGGGACGCTTGCCCCGCAGAAAAAATGGAAGCTTTAGAACAAT
TGCGTATATTGTGGCACGGGGGCCGTATTCACATGGTGGTCGCTAAAAGTAAATGTCCTCCGGGTGTCGACACGGAAGAA
GACCTCGAGCGAGTTAGGGCTTATTTTTAA

Protein sequence :
MEFRVIIPARFDSTRLPGKALVDIAGKPMIQHVYESAIKSGAEEVVIATDDKRIRQVAEDFGAVVCMTSSDHQSGTERIA
EAAVALGFEDDEIIVCLQGDEPLIPPDAIRKLAEDLDEHDNVKVASLCTPITEVDELFNPHSTKVVLNRRNYALYFSHAP
IPWGRDTFSDKENLQLNGSHYCHVGIYAYRVGFLEEYLSWDACPAEKMEALEQLRILWHGGRIHMVVAKSKCPPGVDTEE
DLERVRAYF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-39 43
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-39 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-39 42