Gene Information

Name : tkt (COXBURSA331_A1981)
Accession : YP_001597609.1
Strain : Coxiella burnetii RSA 331
Genome accession: NC_010117
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1805991 - 1807985 bp
Length : 1995 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGCCTTCACGCCGAGACTGTGCCAATGCGATTCGTGCGTTGGCGATGGACGCTGTTCAAAAAGCCAATTCAGGGCACCC
AGGGATGCCCATGGGGATGGCAGATATTGCCGAAGTTTTGTGGCGGGATTTTTTGAAATTCAATCCCGCTAATCTTAATT
GGGTCGATCGCGATCGTTTTGTCTTATCCAATGGTCATGGCGCTATGCTGCAATACGCGTTGCTGCATTTGACCGGGGCC
GGTTTAACCATTGAGGATATTAAACAATTTCGTCAATGGCATTCGCGCACTCCCGGCCACCCGGAGTTCGGTGACACCCC
GGGTGTGGAGACCACCACTGGGCCTCTGGGCCAAGGGCTAGCCACTGGCGTTGGCATGGCAATGGCTGAGCAAATGCTGG
CGGCAACGTTCAATCGCGAAAATTTCCCCATCGTGGATCATTACACTTATGTTTTTGCCGGCGACGGCGATTTAATGGAA
GGTATTTCCCACGAGGCGTGTTCGTTAGCGGGGACATGGGGACTTGGCAAATTGATCGTCTTCTACGACGACAATGGGAT
TTCTATCGACGGTGAAGTCAGCGGTTGGTTCACCGACGATACGCCCAAGCGCTTTGAAGCTTATCATTGGCATGTAGTGC
CGAATGTCGACGGTCATGACCCCGATGCAATTTTGAAAGCGATTGAGGCAGCCCAAAACGTAACGGACAAACCCAGTCTC
ATTTGTTGTAAAACCATCATCGGTTATGGCGCACCCATTTTAGCGGGCAAAGCTGTCACGCATGGGGCCCCCTTAGGCGA
AGAAGAAGTCGCTGGGGTTCGTAAAATTTTAAATTGGCCGCATCCGCCTTTTGAAATCCCCGAGGAGATTTATGCAGCGT
GGAATTGTAAAGAAAAAGGCGAAAAAAACGAAACGCAATGGAATCGACTGTTTACCGAGTACGAAAAACAGCATCCCGAC
TTGGCCAAAGAATTTCGTCGGCGGCAAGAAAAAGAGTTGCCGGAACAATGGGAACAAACAGGGAAAGAGTTACTAGCAAC
GATGCAAGCATCAAAAGAAAATAACGCCACTCGCAAACTTTCTTTAAAATGTTTAAATACATTTGCGCCGTTATTGCCTG
AATTAATCGGCGGCTCCGCGGATTTATCTGAATCCAATTGCACTAAATGGACGGGCGCTATTATTCAGGGTCAGGATAAT
CGTTCGGGAAATTATATCGAATACGGCGTGCGTGAATTCGCCATGACGGCCATAATGAATGGCATGGCGCTGCATGGCGG
ATTTATTCCCTTCGCGGGGACCTTTTTAACTTTCTCCGATTACGCGCGCAATGCGGTGCGGCTTGCAGCGATGATGAAAG
CCCATGCTATTTTCATTTATTCTCACGATTCAATCGGTCTAGGTGAAGACGGACCGACGCACCAGCCGATTGAACAATTG
CCTTCACTACGCATGATTCCGGGTCTGCACGTATGGCGCCCGTGCGATGGGGTGGAAACGGCAGTGGCTTGGAAAAAGAT
AATCGAAGAACCGGGCGCCAATTGCCTTTTATTAACCCGCCAAACGGTCGCTCATCAAGACCGAGACGAAAAACAAATCG
CTCAAATTGTCAAAGGCGGTTACATTTTGTGGGAGTCTGCTGCAAATCCCGAGGTTATTTTAATCGCTTCGGGTTCGGAA
GTGGCTGTTACGATCGAAGCTGCAAAGGCATTAGCGAAGGAAAATATTTCGGTTCGTGTTGTTTCCATGCCCTGTTGCGA
ACTATTTAAAAAGCAAAACACCGATTATCGCAACTCGGTATTGCCCCCGAACGTTAAAAAACGAGTAGCCATCGAGGCCG
CTCATCCCGATTATTGGTATCAATTTGTGGGTTATGAAGGCCGAGTGATCGGCATTGATCGCTTTGGCGCTTCTGCGCCG
TGGCAAGTGGTGTATCGTGAATATGGGTTCACGGTGGAAAATATTCTTAATGTGGTTAATCAACTATATAAATAA

Protein sequence :
MPSRRDCANAIRALAMDAVQKANSGHPGMPMGMADIAEVLWRDFLKFNPANLNWVDRDRFVLSNGHGAMLQYALLHLTGA
GLTIEDIKQFRQWHSRTPGHPEFGDTPGVETTTGPLGQGLATGVGMAMAEQMLAATFNRENFPIVDHYTYVFAGDGDLME
GISHEACSLAGTWGLGKLIVFYDDNGISIDGEVSGWFTDDTPKRFEAYHWHVVPNVDGHDPDAILKAIEAAQNVTDKPSL
ICCKTIIGYGAPILAGKAVTHGAPLGEEEVAGVRKILNWPHPPFEIPEEIYAAWNCKEKGEKNETQWNRLFTEYEKQHPD
LAKEFRRRQEKELPEQWEQTGKELLATMQASKENNATRKLSLKCLNTFAPLLPELIGGSADLSESNCTKWTGAIIQGQDN
RSGNYIEYGVREFAMTAIMNGMALHGGFIPFAGTFLTFSDYARNAVRLAAMMKAHAIFIYSHDSIGLGEDGPTHQPIEQL
PSLRMIPGLHVWRPCDGVETAVAWKKIIEEPGANCLLLTRQTVAHQDRDEKQIAQIVKGGYILWESAANPEVILIASGSE
VAVTIEAAKALAKENISVRVVSMPCCELFKKQNTDYRNSVLPPNVKKRVAIEAAHPDYWYQFVGYEGRVIGIDRFGASAP
WQVVYREYGFTVENILNVVNQLYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 59
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 59