Gene Information

Name : COXBURSA331_A1105 (COXBURSA331_A1105)
Accession : YP_001596859.1
Strain : Coxiella burnetii RSA 331
Genome accession: NC_010117
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase family protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 980313 - 981602 bp
Length : 1290 bp
Strand : +
Note : identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026

DNA sequence :
ATGAACGCCGTCGCAAGGAAAATCGCTGTTATTGGGCTTGGCTATGTGGGTCTTCCCGTTGCTGTTGCTTTTAGCCGTCT
CCAACCGGTCATCGCTTACGACAAAAATTCTGCCCGGATTCGAGCACTTAAACAAGGTTATGATGCCTGCGGCGAAGTTG
ATTCTCAACAGTTACGCACCTGCCAAATTGATTTTACGGACGACCCGGACGATTTAGCAAAAGCTGATTTTTATATCGTT
GCCGTCCCAACGCCCATCGATCAATCAAAACACCCCGATTTATCGCTCCTTCTCAATGCTTCCGAAACTATTGGCCGTTA
TTTAAAACGGGGGGATATCGTTGTTTTTGAATCGACCGTTTACCCGGGCGTCACGGAAGAAGAATGTGCGCCCGTTCTTG
AAAAGGCGTCAGGCCTTAAATATGGCGTTGATTTTACGCTGGGATATTCCCCCGAACGAATTAACCCCAGCGACAAAACG
CATCGGTTTGAAACGATCACCAAAATCGTATCGGGCTCTCATCCTGAAACTTTAGATATTGTCGCCCATGTCTATGGCAG
TGTGATAACCGCCGGCATCTACCGCGCTCCTAGCATTCGCACAGCAGAAGCAGCCAAAGTCATTGAGAATACCCAGCGGG
ATTTAAACATCGCTTTAATGAATGAGCTGGCGATTATTTTTAAGCGGATGGATATCGACACTCAAGAAGTGTTAGCCGCT
GCTGGAACTAAATGGAATTTTTTGCCTTTTAAACCCGGCTTGGTGGGGGGGCACTGCATCGGCGTCGATCCTTATTATCT
CACCTACCAGGCTCAGCGCTATGGCTATAATCCTCAAGTGATCCTTGCCGGTCGCCGTATCAACGATACGATGGGTAAAT
ACATTGCGGAACAAACGATTAAACAAATGATTCACGCGGGTTATACCATTAAAGGCGCTAAGGTGGCTGTTTTGGGTCTC
ACGTTTAAAGAAAATTGCCCCGATCTGCGAAATTCAAAAGTCATCGATATTATCGAGGAATTAAATGATTACGGCATTGA
ATGCGTGGTGCACGATCCTCTTGCCGATCCTGAGGTAGCTAAGCAACTCTATAATATAGATCTTAAATCGTGGGATGAGA
TTCACGATGTGGATTCTTTTGTATTAGCCGTTGCTCATGACCAATTTCACCAATATTCTTTAGAAGACTATCACGCCAAA
TTGGCTCATCATTCGATTATTGTTGATGTCAAAAATGTGTTAAATCCACAAGATTGTAAATCAAATGGCATCACCTTGTG
GAGATTGTAA

Protein sequence :
MNAVARKIAVIGLGYVGLPVAVAFSRLQPVIAYDKNSARIRALKQGYDACGEVDSQQLRTCQIDFTDDPDDLAKADFYIV
AVPTPIDQSKHPDLSLLLNASETIGRYLKRGDIVVFESTVYPGVTEEECAPVLEKASGLKYGVDFTLGYSPERINPSDKT
HRFETITKIVSGSHPETLDIVAHVYGSVITAGIYRAPSIRTAEAAKVIENTQRDLNIALMNELAIIFKRMDIDTQEVLAA
AGTKWNFLPFKPGLVGGHCIGVDPYYLTYQAQRYGYNPQVILAGRRINDTMGKYIAEQTIKQMIHAGYTIKGAKVAVLGL
TFKENCPDLRNSKVIDIIEELNDYGIECVVHDPLADPEVAKQLYNIDLKSWDEIHDVDSFVLAVAHDQFHQYSLEDYHAK
LAHHSIIVDVKNVLNPQDCKSNGITLWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-119 59
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-102 53
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-102 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
COXBURSA331_A1105 YP_001596859.1 UDP-glucose/GDP-mannose dehydrogenase family protein VFG0431 Protein 1e-102 53