Gene Information

Name : SPAB_05347 (SPAB_05347)
Accession : YP_001591453.1
Strain : Salmonella enterica SGSC4150; SPB7
Genome accession: NC_010102
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 4501242 - 4503251 bp
Length : 2010 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGGTTGTTTATCTGCGAAAAGCCCTCACAGGGGCGAGATCTTGCGAATGTTTTGGGTGCCACCCGACGTGGCGACGG
TTTTCTAACTGGCCCTGGCGTCACTGTTACCTGGGCAGTAGGGCATTTGCTGGAGACCGCACCGCCTGAAGCATACGGTC
AACAGTATGGCAAACCATGGTCGCTCTCTGCTCTGCCGATCCTGCCTTCCCCATGGCAGGTGGTGGTAAAAAAGGAGACG
AAGTCTCAGTTCAAGGTTATTGAGCGGCTGCTGCGCCAGGTCGATGATGTGGTTATCTCCACTGATGCGGACCGGGAAGG
AGAAGTAATTGCCCGTGAATTGCTGGAATACTGCCGCTGGGACGGTCCTGTACAGCGGCTTTGGCTTTCTGCCCTTGATG
AAATGAGCATCCGTGCAGCTCTCCAGGATCTGCGACCGGGTGCCGAAACTCTTGGAATGTATCATGCGGGACTTGGTCGC
GCTCGTGCCGACTGGCTCATTGGAATGAATCTGTCTCGTCTGTATACACTGCTTGCAGTACAGTCAGGATTCGACGGTGT
GATTTCTGTCGGGCGGGTGCAGACTCCCACCCTGGCACTGGTTGTCCGGCGTGATCGGGAGATAGCGACATTCGTCCCAA
AACCTTTCTGGCAGGTTAAGGCGCTTCTGAGTGCGGGAGGGAGAACTTTTCCGGCGCAATGGGTACCTGCAAAGGTTTAT
ACCGACGAAGAAAAACGCTGTGTACACCAAAATATAGCGCAGCAGGTAGCGCATCTTTGCCGGCAGGCTGGAGCAGCGAC
CGTAACAGAATGTGAGACGAAGCGTGAAAAAGCGGCAGCACCGCTGGCTTTTTCGCTCGGCACTTTACAACAGGCCTGTG
GCCTGCTCTGGGATATGTCACCCCAGCAGGTGCTTGACACTGCACAGAGCCTCTATGAGAAACACAAGGCAACCACTTAT
CCACGAACTGATTGTGGATACCTTCCTGAGTCTATGCGTGAGGAAATCCCCTCGGTGCTTTCCGCTATTGGCCTGTCTGA
TCCAGAGTGTAGTTCTCTTCTTTCAGGTCTAAATACTTCGTTTGTTTCGCGTATATGGAACGACAAAAAAATCACAGCTC
ACCATGGCATTATCCCTACCCGAAACGCGTTTAAGTTTTCTGCGTTAAGTGAGGCAGAGCGAAGGGTATACACCCTTATC
CGCCGAAATTATCTGGCACAATTTCTTCCCCTGCACGAATCTGATATTACTCGTCTGCAGTTTGACATTGGCGGGCAACT
GTTCCGCACAACAGGAAGGACGGAGATTGTAATGGGCTGGAAGGTCCTTTTCAGTAAGGAGGAAGAGGATAGTGCAGGGG
ATGATGATCTCAGTATTGAACTTCCTCCTCTCAGGCAGGGTGACCGTTGCGGAGTAAACGGTGCAGAGGTCGTGCAGCAA
ATGACTCGTCCGCCGGCTCACTATACTTTCGCAACACTCATCGGCGCTATGATGAACGCGTCAGCGTTTGTTACCGATAT
TGCTCTTCGTAAGGTACTGAAGGACAACGCCGGATTAGGCACGGAAGCCACCCGTGCAGGTATCGTTGAGCAACTGCTGA
ACCGCAGATTTATTGTGCGCAAAGGTAAGCAGCTTCGCGCGACTGATCTTGGTGCTGATGTCATTGATGCTCTGCCCTCG
CAGTTAACCGACCCGGGAATGACTGCACTTTGGGAACAGGCTCTGGATGAAGTAGCAGAAGGACGCCTTACCCTGAATGA
TTTTTTGCAGCGACAGGTCGGATGGACCCGTAACCTTGTCAGCATGGGAGGACAGCAGCGGGTGAGCATTAGAATACCAC
CCACACCATCGTGCCCTTTATGTGGGGGGAAAACTCGCCTAAAAAAAGGACAGAAAGGAGAGTTTTGGGGGTGTACTCGT
TATCCTGATTGCAAAGGAATCATCAACAACGACACCCAGAAACGTAAAAGCGCGCGTAGCTCTAAGGCTGTAAAACCAAA
GAATAATTAA

Protein sequence :
MRLFICEKPSQGRDLANVLGATRRGDGFLTGPGVTVTWAVGHLLETAPPEAYGQQYGKPWSLSALPILPSPWQVVVKKET
KSQFKVIERLLRQVDDVVISTDADREGEVIARELLEYCRWDGPVQRLWLSALDEMSIRAALQDLRPGAETLGMYHAGLGR
ARADWLIGMNLSRLYTLLAVQSGFDGVISVGRVQTPTLALVVRRDREIATFVPKPFWQVKALLSAGGRTFPAQWVPAKVY
TDEEKRCVHQNIAQQVAHLCRQAGAATVTECETKREKAAAPLAFSLGTLQQACGLLWDMSPQQVLDTAQSLYEKHKATTY
PRTDCGYLPESMREEIPSVLSAIGLSDPECSSLLSGLNTSFVSRIWNDKKITAHHGIIPTRNAFKFSALSEAERRVYTLI
RRNYLAQFLPLHESDITRLQFDIGGQLFRTTGRTEIVMGWKVLFSKEEEDSAGDDDLSIELPPLRQGDRCGVNGAEVVQQ
MTRPPAHYTFATLIGAMMNASAFVTDIALRKVLKDNAGLGTEATRAGIVEQLLNRRFIVRKGKQLRATDLGADVIDALPS
QLTDPGMTALWEQALDEVAEGRLTLNDFLQRQVGWTRNLVSMGGQQRVSIRIPPTPSCPLCGGKTRLKKGQKGEFWGCTR
YPDCKGIINNDTQKRKSARSSKAVKPKNN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 61
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 61
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 61
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 0.0 58
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-174 53
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 3e-172 52
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 1e-160 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-155 50