Gene Information

Name : leuS (SPAB_02902)
Accession : YP_001589099.1
Strain : Salmonella enterica SGSC4150; SPB7
Genome accession: NC_010102
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 2413242 - 2415824 bp
Length : 2583 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCCAAAGTACAGCTTCACTGGGATGAGAAGCGCACATTTGAAGTGAC
CGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCCTATCCTTCTGGCCGACTACACATGGGCCACGTAC
GTAACTACACCATCGGCGACGTGGTTGCCCGCTACCAGCGTATGCTGGGCAAAAACGTGCTGCAGCCAATCGGCTGGGAC
GCCTTCGGCCTGCCGGCGGAAGGCGCGGCGGTGAAGAACAACACCGCGCCGGCACCGTGGACGTACGACAACATCGCGTA
TATGAAAAACCAGCTCAAAACGCTGGGTTTTGGCTATGACTGGAGCCGTGAAATCGCGACCTGCACCCCGGAATACTACC
GTTGGGAACAGAAGTTCTTCACCGAGCTGTATAAAAAAGGCCTGGTGTACAAGAAGACTTCTGCCGTTAACTGGTGCCCG
AACGATCAGACCGTTCTCGCCAACGAACAGGTGATCGACGGCTGCTGCTGGCGCTGCGACACCAAAGTTGAGCGTAAAGA
GATCCCACAGTGGTTTATCAAAATCACCGCTTACGCAGACGAGCTGTTGCGCGATCTGGATAAGCTGGACCACTGGCCTG
ATACCGTAAAAACGATGCAGCGCAACTGGATTGGCCGCTCTGAAGGCGTGGAAATCACCTTCGATGTGAAGGGTTACGAT
AACACCCTGACCGTCTATACCACCCGTCCAGATACCTTTATGGGCGCCACTTACCTGGCGGTGGCCGCCGGTCATCCGCT
GGCGCAAAAAGCGGCGGCGAACAACGCCGAACTGGCGGCGTTCATCGACGAATGCCGTAACACCAAAGTGGCCGAAGCCG
AAATGGCGACCATGGAGAAAAAAGGCGTCGACACCGGCTATAAAGCGATTCATCCGTTAACTGGCGAAGAGATCCCGGTC
TGGGCGGCAAACTTTGTCCTGATGGAGTACGGCACTGGCGCGGTGATGGCCGTTCCGGGTCACGATCAGCGCGACTACGA
ATTTGCCTCCAAATACGGTTTGACCATCAAGCCGGTGATTCTGGCCGCCGACGGTTCCGAGCCAGATCTTTCCGAACAGG
CGCTGACCGAAAAAGGCGTGCTGTTTAACTCCGGCGAGTTCGACGGCCTGGCCTTTGAAGCGGCGTTTAACGCCATTGCC
GATAAACTGGCGGAAAAAGGCGTCGGCGAACGTAAAGTGAACTACCGTCTGCGCGACTGGGGCGTTTCCCGTCAGCGTTA
CTGGGGCGCGCCGATCCCGATGGTCACCCTGGAAGACGGCACTGTGCTGCCGACGCCGGAAGATCAACTGCCGGTTATTC
TGCCGGAAGACGTCGTCATGGACGGCATCACCAGCCCGATCAAGGCCGATCCTGAGTGGGCGAAAACCACCGTTAACGGT
ATGCCGGCGCTGCGTGAAACCGACACCTTCGACACCTTTATGGAATCGTCATGGTACTACGCGCGTTACACCTGCCCGCA
GTATCAGGAAGGAATGCTGGATTCGAAAGCGGCAAACTACTGGCTGCCGGTCGACATCTACATCGGCGGTATTGAACATG
CCATCATGCACCTGCTCTACTTCCGTTTCTTCCATAAGCTGATGCGCGATGCGGGCATGGTCACCTCTGACGAGCCGGCT
AAACAGTTGCTGTGCCAGGGCATGGTACTGGCGGATGCGTTCTATTATGTCGGCGAGAACGGCGAACGTAACTGGGTTTC
GCCAGTTGACGCTATCGTCGAGCGCGATGAAAAAGGCCGCATCGTCAAAGCAAAAGACGCAGCGGGTCATGAGCTGGTCT
ACACTGGCATGAGTAAAATGTCCAAGTCGAAAAATAACGGTATCGACCCGCAGGTAATGGTTGAACGTTATGGCGCGGAT
ACGGTACGCCTGTTTATGATGTTCGCTTCTCCGGCGGATATGACTCTGGAATGGCAGGAGTCCGGCGTAGAAGGCGCAAA
CCGCTTTATTAAACGCGTCTGGAAGCTGGTTTACGAACACACCGCTAAAGGTTCTGTCGCGGCGCTGAACGTCGATGCGC
TGAGCGAAGATCAAAAAGCGCTGCGTCGCGATGTGCATAAAACCATTGCCAAAGTGACCGATGATATCGGCCGCCGTCAG
ACGTTCAACACCGCCATTGCGGCGATCATGGAGTTGATGAACAAACTGGCGAAAGCCCCGCAGGAAGGCGAACAAGACCG
CGCACTGCTTCAGGAAGCGCTGCAGGCCGTCGTGCGTATGCTTAACCCGTTCACCCCGCACGTCTGCTTTACCTTGTGGC
AGGAACTGGGTGGCGAAGGCGATATCGACAACGCACCGTGGCCGGTTGCCGACGAGCAGGCAATGGTGGAAAACACCACG
CTGGTTGTCGTGCAGGTTAACGGTAAAGTTCGCGGTAAGATCACCGTTGCGGTGGATGCCACCGAAGAACAGGTGCGTGA
ACGTGCAGGCCAGGAACATCTGGTGGCAAAATATCTTGATGGCGTTACCGTGCGTAAAGTGATTTACGTTCCGGGTAAAC
TCCTCAATCTGGTTGTTGGCTAA

Protein sequence :
MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYD
NTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPV
WAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIA
DKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG
MPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPA
KQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGAD
TVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGSVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQ
TFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTT
LVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-151 42