Gene Information

Name : murD (SPAB_00160)
Accession : YP_001586435.1
Strain : Salmonella enterica SGSC4150; SPB7
Genome accession: NC_010102
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 141508 - 142824 bp
Length : 1317 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGCTGATTACCAGGACAAAAACGTCGTCATTATCGGTCTGGGCTTAACCGGACTCTCTTGCGTGGACTTTTTTCTCGC
CCGCGGCGTGACGCCGCGGGTGATGGATACTCGCGTGACGCCGCCGGGTCTGGATAAGCTGCCGCAAGATGTTGAGCGTC
ACGTTGGCGGCCTGAACGACGAGTGGCTCTTAGCGGCGGATTTAATCGTCGCCAGCCCTGGTATTGCTCTGGCGCATCCC
TCTCTTAGCGCTGCCGCCAGCGCTGGAGTGGAAATTGTCGGCGATATCGAACTGTTTTGCCGCGAAGCGCAGGCGCCGAT
TGTGGCTATCACCGGCTCAAACGGCAAAAGCACCGTGACCACCTTAGTGGGCGAGATGGCGAAGGCGGCGGGCGTCAATG
TCGGTGTTGGCGGCAATATCGGTCTTCCGGCGCTGATGCTGCTGGATGCCGATCGCGAATTGTACGTGCTGGAATTATCC
AGTTTCCAACTGGAAACCACGTCAAGTTTGCAAGCGGCGGCGGCAACGGTGCTCAACGTCACTGAAGATCATATGGACCG
GTATCCGTTTGGTTTGCAACAGTACCGGGCGGCGAAACTGCGCGTCTACGAGAAGGCGAAAGTGTGCGTAGTGAATGCCG
ATGACGCGTTGACGATGCCGGTTCGCGGGGCCGATGAACGATGCGTCAGCTTTGGCGTCAATATGGGTGATTATCACCTT
AATCGTCAGCAGGGCGAAACCTGGCTGCGAGTCAAAGGCGAGAAGGTGCTGAACGTGAAAGAGATGAAGCTTTCCGGTCA
GCATAACTATACCAATGCGTTAGCGGCGCTGGCGCTGGCGGATGCCGTAGGTCTGCCGCGCGCCAGCAGTTTGAAGGCGT
TGACGACATTTACCGGTCTGGCGCATCGCTTCCAGCTGGCGTTGGAGCATAACGGCGTACGTTGGATCAACGACTCGAAA
GCGACCAACGTCGGCAGTACCGAAGCGGCGCTAAACGGTTTGCATGTGGACGGTACGCTGCATCTGCTGCTGGGCGGCGA
CGGTAAGTCGGCAGACTTTTCTCCGCTGGCGCGCTATCTGACCGGCGATCGTATCCGCCTGTATTGCTTTGGGCGCGATG
GCGCGCAGCTTGCCGCGCTGCGTCCGGAAATCGCCCAACAGACTGAGACGATGGAAGAGGCGATGCGTTTGCTGGCGCCG
CGCGTTCAGCCGGGTGATATGGTGCTGCTGTCGCCCGCCTGCGCCAGCCTCGATCAGTTTAAAAATTTTGAGCAACGGGG
CGATGTCTTTACCCGTCTGGCGAAGGAGTTAGGTTGA

Protein sequence :
MADYQDKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRVTPPGLDKLPQDVERHVGGLNDEWLLAADLIVASPGIALAHP
SLSAAASAGVEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDADRELYVLELS
SFQLETTSSLQAAAATVLNVTEDHMDRYPFGLQQYRAAKLRVYEKAKVCVVNADDALTMPVRGADERCVSFGVNMGDYHL
NRQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAVGLPRASSLKALTTFTGLAHRFQLALEHNGVRWINDSK
ATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLARYLTGDRIRLYCFGRDGAQLAALRPEIAQQTETMEEAMRLLAP
RVQPGDMVLLSPACASLDQFKNFEQRGDVFTRLAKELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 2e-52 44
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 2e-52 44