Gene Information

Name : fliI (SPAB_01176)
Accession : YP_001587424.1
Strain : Salmonella enterica SGSC4150; SPB7
Genome accession: NC_010102
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1048417 - 1049787 bp
Length : 1371 bp
Strand : -
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGACCACGCGTTTGACCCGCTGGCTTACCGCGCTCGACAACTTTGAAGCAAAAATGGCGTTATTGCCGGCGGTGCGTCG
TTATGGACGTTTAACCCGCGCCACTGGCCTGGTACTGGAGGCCACCGGTCTCCAGCTTCCGCTGGGCGCCACCTGCATTA
TTGAGCGCCAGGACGGCCCTGAAACCAAAGAGGTGGAATCGGAAGTCGTCGGTTTTAACGGCCAGCGTCTGTTTTTAATG
CCGCTGGAAGAGGTTGAAGGCATTCTGCCCGGTGCCCGCGTTTACGCCCGTAACGGGCATGGCGACGGTCTGCAAAGCGG
CAAACAGTTACCGCTCGGCCCGGCCCTGCTTGGTCGGGTGCTGGATGGCGGCGGTAAACCGCTCGACGGACTGCCTGCGC
CGGATACGCTGGAAACCGGCGCGTTAATCACGCCGCCGTTTAACCCGCTACAGCGAACGCCAATCGAACATGTGTTGGAT
ACCGGCGTACGCGCTATCAACGCGTTGTTAACCGTAGGGCGCGGTCAGCGTATGGGACTCTTTGCCGGTTCCGGCGTCGG
TAAATCGGTTCTGCTTGGCATGATGGCGCGCTACACACGGGCGGACGTGATTGTCGTGGGACTTATCGGCGAACGTGGCC
GCGAAGTTAAAGATTTTATCGAAAATATTCTCGGCCCCGACGGTCGCGCGCGTTCGGTGGTGATTGCCGCCCCGGCGGAT
GTTTCGCCGCTGCTGCGAATGCAGGGCGCCGCCTATGCCACCCGCATCGCCGAAGACTTTCGCGATCGCGGACAGCATGT
GTTGCTGATTATGGATTCGCTGACGCGCTATGCGATGGCGCAGCGTGAAATTGCGCTGGCAATCGGCGAACCGCCAGCCA
CCAAAGGTTATCCGCCCTCGGTGTTCGCAAAGCTGCCGGCGCTGGTCGAACGTGCCGGTAATGGCATCCACGGCGGCGGC
TCTATCACCGCGTTTTATACCGTATTGACCGAGGGGGACGACCAACAAGATCCCATTGCCGACTCGGCACGCGCAATCCT
CGACGGGCACATTGTCTTGTCCCGCCGTCTGGCGGAGGCCGGGCACTATCCGGCCATTGATATCGAGGCGTCAATCAGCC
GGGCGATGACCGCGCTCATTACCGAGCAGCACTATGCGCGGGTACGGCTATTTAAACAGTTGCTTTCCAGTTTCCAGCGT
AACCGCGATCTGGTCAGCGTCGGCGCCTATGCCAAAGGCAGCGATCCGATGCTCGATAAAGCCATTACCTTATGGCCGCA
ACTGGAAGCGTTTTTACAGCAAGGCATTTTTGAACGGGCCGACTGGGAAGACTCTCTGCAGGCGCTCGATTTAATTTTCC
CGACGGTGTGA

Protein sequence :
MTTRLTRWLTALDNFEAKMALLPAVRRYGRLTRATGLVLEATGLQLPLGATCIIERQDGPETKEVESEVVGFNGQRLFLM
PLEEVEGILPGARVYARNGHGDGLQSGKQLPLGPALLGRVLDGGGKPLDGLPAPDTLETGALITPPFNPLQRTPIEHVLD
TGVRAINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKDFIENILGPDGRARSVVIAAPAD
VSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGIHGGG
SITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALITEQHYARVRLFKQLLSSFQR
NRDLVSVGAYAKGSDPMLDKAITLWPQLEAFLQQGIFERADWEDSLQALDLIFPTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-77 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-76 48
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 5e-78 48
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-78 48
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 5e-78 48
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-77 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-77 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-75 47
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-75 47
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-69 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-63 46
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-63 46
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-63 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-63 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-63 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-68 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-68 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-67 45
escN AAC38383.1 EscN Virulence LEE Protein 1e-67 45
escN AAC31513.1 L0034 Virulence LEE Protein 1e-67 45
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-67 45
escN CAI43874.1 EscN protein Virulence LEE Protein 9e-68 45
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-67 45
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-66 45
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-67 45
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-67 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-63 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-62 44
escN AAL57542.1 EscN Virulence LEE Protein 2e-67 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-67 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-67 44
escN AAK26715.1 EscN Virulence LEE Protein 2e-67 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-66 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-66 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-66 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 8e-71 43
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 5e-68 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-60 41
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-60 41
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_001587424.1 flagellum-specific ATP synthase VFG2331 Protein 9e-168 85
fliI YP_001587424.1 flagellum-specific ATP synthase VFG2499 Protein 8e-140 70
fliI YP_001587424.1 flagellum-specific ATP synthase VFG1254 Protein 1e-114 61
fliI YP_001587424.1 flagellum-specific ATP synthase VFG0048 Protein 1e-76 46
fliI YP_001587424.1 flagellum-specific ATP synthase VFG0192 Protein 8e-68 46
fliI YP_001587424.1 flagellum-specific ATP synthase VFG0515 Protein 2e-63 46
fliI YP_001587424.1 flagellum-specific ATP synthase VFG2144 Protein 1e-78 45
fliI YP_001587424.1 flagellum-specific ATP synthase VFG0812 Protein 7e-68 45
fliI YP_001587424.1 flagellum-specific ATP synthase VFG0730 Protein 8e-68 45
fliI YP_001587424.1 flagellum-specific ATP synthase VFG0390 Protein 5e-68 43
fliI YP_001587424.1 flagellum-specific ATP synthase VFG2459 Protein 8e-63 42