Gene Information

Name : umuC (SPAB_01145)
Accession : YP_001587394.1
Strain : Salmonella enterica SGSC4150; SPB7
Genome accession: NC_010102
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : -
Position : 1028549 - 1029817 bp
Length : 1269 bp
Strand : +
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTCGCGCTCTGCGATGTTAATAGCTTTTACGCCTCCTGCGAAACGGTCTTTCGTCCTGATTTATGTGGCCGACCGGT
GGTGGTGTTATCAAACAATGATGGCTGCGTTATCGCGTGTAGCGCCGAGGCGAAACAGCTCGGTATCGCACCAGGTGAGC
CATACTTCAAACAGAAAGAACGCTTCCGGCGATCCGGTGTTGTTTGCTTCAGCAGTAATTACGAGCTTTACGCTGATATG
TCGAACCGGGTAATGACCACACTCGAGGAGATGGTGCCGCGGGTAGAAATTTACAGCATTGATGAGGCTTTTTGTGATCT
GACGGGGGTACGAAACTGCCGGGATCTGACAGATTTCGGGCGCGAGATAAGAGCGACGGTCCTGAAGCGCACGCACCTGA
CTGTCGGTGTAGGCATTGCCCAGACGAAAACCCTTGCCAAGCTGGCTAACCATGCTGCGAAAAAGTGGCAGCGCCAGACC
GACGGGGTGGTTGACCTGTCGAACATCGATCGCCAGCGTCGGCTGCTGGCCCTGATACCCGTAGAGGATGTCTGGGGTGT
CGGCAGACGCATCAGTAAGAAGCTAAATTCCCTGGGCATCAAGACTGCTCTCGATCTCTCTGAACAAAGTACCTGGATCA
TCAGGAAACACTTCAATGTCGTGCTGGAGCGTACCGTGAGAGAGCTTCGCGGAGAGCCATGTCTGGAGCTTGAAGAGTTT
GCGCCGGCAAAGCAGGAAATCGTTTGTAGCCGCTCTTTCGGCGAGCGGGTCACAGACTATGAGGAAATGCGCCAGGCTGT
TTACAGCTACGCTGCGCGCGCGGCAGAAAAACTCCGCGGCGAGCACCAGTACTGCCGTTTCATTTCAACATTCGTCAAAA
CATCACCCTTTGCCCTGAACGAGCCCTACTACGGTAACAGCGCCGCGGTGACGCTTCTCACCCCCACGCAGGATTCACGT
GACATTATCAATGCGGCTGTGAAATGTCTGGATAAAATCTGGCGCGACGGCCATCGCTACCAGAAAGCGGGGGTGATGCT
GGGTGACTTCTTCAGCCAGGGCGTAGCGCAACTCAACCTTTTCGACGATAACGCGCCGCGCGCCGGTAGTGCGAAGTTGA
TGGAAGTACTGGACCATCTTAACGCAAAAGACGGGAAGGGGACGCTGTACTTCGCCGGGCAGGGGATGTCGCAACAGTGG
GCTATGAAGCGAGAAATGCTTTCGCCTCGGTACACCACAAGATACTCTGATCTACTGCGTGTTAAGTAA

Protein sequence :
MFALCDVNSFYASCETVFRPDLCGRPVVVLSNNDGCVIACSAEAKQLGIAPGEPYFKQKERFRRSGVVCFSSNYELYADM
SNRVMTTLEEMVPRVEIYSIDEAFCDLTGVRNCRDLTDFGREIRATVLKRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
DGVVDLSNIDRQRRLLALIPVEDVWGVGRRISKKLNSLGIKTALDLSEQSTWIIRKHFNVVLERTVRELRGEPCLELEEF
APAKQEIVCSRSFGERVTDYEEMRQAVYSYAARAAEKLRGEHQYCRFISTFVKTSPFALNEPYYGNSAAVTLLTPTQDSR
DIINAAVKCLDKIWRDGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRAGSAKLMEVLDHLNAKDGKGTLYFAGQGMSQQW
AMKREMLSPRYTTRYSDLLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 8e-123 63
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 8e-123 63
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 7e-91 50
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 2e-78 50