Gene Information

Name : thyA (lhv_0955)
Accession : YP_001577339.1
Strain : Lactobacillus helveticus DPC 4571
Genome accession: NC_010080
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 938847 - 939803 bp
Length : 957 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGGCGATTCTTGAACAACCATATTTAGATCTATTGCAAAAAATTATGTCAGAAGGGCATGGTAAAGATGATCGGACCGG
GACGGGAACCAGAAGTTACTTCGGTGCTCAGATGCGTTTTGATCTTTCGCAAGGTTTTCCATTGTTAACTACTAAGAAGG
TGCCATTCGGCTTAATTAAAAGCGAATTGCTTTGGTTTTTGAGGGGAGATACCAATATCCGTTTTTTGCTTGAACATAAT
AACCATATCTGGGATGAATGGGCTTTTAAGAACTGGGTAAATAGCAGCGAATATCAAGGCCCTGATATGACGGATTTTGG
CTTGCGCAGTCAAAGCGACCCAGAATTTAACAAGATTTATCAGGCAGAGATGAAAAAGTTTGATCAGCGGATTTTGGATG
ACGAAGATTTTGCTAAAAAATATGGCAATCTAGGTGATGTCTATGGTGCGCAATGGCGACATTGGGAAAAGCGCGAAGGC
GGATTTATTGATCAGATTGCTGACGTGATTAAGCAAATTAAGGAAACGCCAGATTCTCGGCGCATGATTGTTACGGCATG
GAATCCTGAAGATGTGCCAACTAGTGCACTTCCACCTTGTCATGTCATGTTTCAATTTTATGTGGTAGATGGCAAAATCA
GCGTGCAGCTTTATCAAAGATCTGGCGATATGTTCTTGGGCGTGCCGTTTAACATTGCATCTTATTCGCTTTTGCTTAAT
TTGATTGCCCGAGAAACTGGTTTGCAAGTTGGTGAGTTTATCCATACTTTGGGGGATGCTCATATTTATCGCAACCACCT
TAAGCAAGTTGAAGAATTGCTTAGCCGTAAGCCATATGATTCACCACAATTATGGCTTAATCCTGAAAAGAAAAATATTG
CAGATTTTGAGATGAAGGATATTAAGGTAGTCGATTATCAGCATCATGGTACGATTAAAGCACCTGTTGCAGTTTAG

Protein sequence :
MAILEQPYLDLLQKIMSEGHGKDDRTGTGTRSYFGAQMRFDLSQGFPLLTTKKVPFGLIKSELLWFLRGDTNIRFLLEHN
NHIWDEWAFKNWVNSSEYQGPDMTDFGLRSQSDPEFNKIYQAEMKKFDQRILDDEDFAKKYGNLGDVYGAQWRHWEKREG
GFIDQIADVIKQIKETPDSRRMIVTAWNPEDVPTSALPPCHVMFQFYVVDGKISVQLYQRSGDMFLGVPFNIASYSLLLN
LIARETGLQVGEFIHTLGDAHIYRNHLKQVEELLSRKPYDSPQLWLNPEKKNIADFEMKDIKVVDYQHHGTIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 6e-98 61