Gene Information

Name : secA (lhv_0720)
Accession : YP_001577153.1
Strain : Lactobacillus helveticus DPC 4571
Genome accession: NC_010080
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 701073 - 703472 bp
Length : 2400 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGCTAAATATTTTAAAGAAATTATATAACGACGATAAAAGAGAACTTAAGAAATTCGAAAAATATGCCAACAAAGTAGA
AGGCTATGCTGATGAAATGAGCAAGCTTACCGATGAACAATTGCAAGCTAAGACTCCAGAGTTTCGTGAACGGATCAAGA
AGGGTGAAAGCTTAGATGATCTTTTGCCAGAAGCATTTGCTGTAGCACGTGAAGGTGCTAAGCGTGTTCTTGGTCTTTAC
CCATTCCACGTTCAAATTTTAGGTGGTATCGCACTTCACTTCGGTAACATTGCCGAAATGATGACGGGTGAAGGTAAGAC
TTTGACAGCTACTATGCCTGTTTATTTGAATGCCCTTGAGGGGAAAGGCGTTCACGTTGTTACTGTTAACGAATATCTTT
CTAGTCGTGACGAAGAAGAAATGGGTCAACTCTATAAGTGGCTTGGTTTGACTGTAGGCTTGAACTTGAATTCAATGTCC
CCAGATGAAAAGCGCGAAGCTTATAATTGTGATGTTACTTACTCAACTAACTCAGAATTAGGCTTTGACTATTTGCGTGA
CAACATGGTTGTTTATAAAGAACAAATGGTTCAACGTCCGCTTAATTACGCTATCATCGACGAAGTTGACTCAATTTTGA
TTGATGAAGCTAGAACGCCATTGATTATTTCTGGTGAAGCTGAACAAGCAAACAGTGACTACATTCGTGCAGACCGCTTT
GTTAAGAATTTATCAGAAGATAAAAGCGATGACGATGTGGATGATGACGAAGATTATGGCGATTACAAGATCGATTGGCC
AACTAAGACTATTTCTCTTACCAGAACTGGTATTGAGAAGGCATGTAAACACTTTGGTTTAAGAAACTTATATGATGTTG
AAAACCAAAAGCTGGTTCACCATATCGATCAAGCTCTTCGTGCTAACTACATCATGCTTAAGGACATTGACTACGTTGTT
CAAGATGGTGAAGTTTTGATCGTTGACTCATTCACTGGTCGTGTAATGGAAGGACGGCGTTATTCAGACGGATTGCACCA
AGCCATTGAAGCTAAGGAAGGCGTTAAGATTCAAGAAGAATCTAAGACTCAAGCTACAATTACTTACCAGAATTTCTTCA
GAATGTACAAGAAGCTATCTGGTATGACTGGTACTGCTAAGACTGAAGAAGAAGAATTCCGTGAAATCTACAACATGCAG
GTAATCACAATTCCAACTAACCGTCCAATTGCCAGAAAAGATATGCCTGATATTTTGTACCCAACTTTGGATTCAAAATT
CCATGCTGTAGTTGAAGAAATTAAGAAGCGCCATGCTAATGGTCAACCTGTTTTGGTTGGTACTGTTGCCATTGAAAGTT
CAGAAAGACTTAGCCACTTGCTTGATGAAGCAGGAATTCCACATGCTGTTTTGAACGCTAAGAATCACGCTAAGGAAGCT
CAAATCATTATGAATGCCGGTCAACGTGGAGCTGTTACTATTGCTACTAACATGGCTGGTCGTGGTACTGATATTAAGCT
TGGGCCTGGTGTGAAAGAACTTGGTGGTTTAGCCGTAATTGGTACTGAACGACATGAATCACGTCGTATTGATAACCAGC
TTCGTGGTCGTTCTGGTCGTCAGGGTGACCCTGGTTATACTCGTTTCTATTTGTCACTTGAAGATGACTTGATGAAGCGT
TTCGGTGGAGATCGTGTTAAGGATTTCTTAGATCGTTTATCAGATAATGATGATGATAAAGTGATTGAAAGTCGTTTGAT
TACCCGTCAAGTGGAATCAGCTCAAAAACGTGTTGAAGGTAACAACTACGATATTCGTAAACAGACTTTGCAATACGATG
ATGTTATGCGTATTCAACGTGAAATTATTTACGGTGAAAGAATGCAAGTAATTGATGCTGACAAGTCATTGAAGAATGTT
TTGATTCCAATGATTCACCGTACAATTGATAGTCAAGTTGATATGTTTACTCAAGGCGATAGAAGTGAATGGCGTCTTGA
TTCATTGCGCGACTTTATTTCTTCAAGTTTGACTTCTGAACAAGTTACAGACTCAATTGATTTTAAGACTATCAGTGTTG
AAGACTTAAAGAAAAAGTTATACGACATTGTAGAAAAGAACTTCGAAGATAAAGAAAAAGCATTGGGCGATCCTAGTCAA
ATGCTTGAATTCGAAAAGGTTGTTATCTTGCGTGTTGTTGATGATCGCTGGACTGATCATATTGATGCAATGGATCAATT
GCGTCAATCAATTGGTCTTCGTGGTTATGGACAGCTTAATCCGCTTGTTGAATATCAAGATTCTGGTTACAGAATGTTTG
AAGAAATGATTTCAAATATTGAATTTGATGTAACTCGTTTGTTCATGAAGGCTGAAATTAGACAAAATATTAGTCGTTAA

Protein sequence :
MLNILKKLYNDDKRELKKFEKYANKVEGYADEMSKLTDEQLQAKTPEFRERIKKGESLDDLLPEAFAVAREGAKRVLGLY
PFHVQILGGIALHFGNIAEMMTGEGKTLTATMPVYLNALEGKGVHVVTVNEYLSSRDEEEMGQLYKWLGLTVGLNLNSMS
PDEKREAYNCDVTYSTNSELGFDYLRDNMVVYKEQMVQRPLNYAIIDEVDSILIDEARTPLIISGEAEQANSDYIRADRF
VKNLSEDKSDDDVDDDEDYGDYKIDWPTKTISLTRTGIEKACKHFGLRNLYDVENQKLVHHIDQALRANYIMLKDIDYVV
QDGEVLIVDSFTGRVMEGRRYSDGLHQAIEAKEGVKIQEESKTQATITYQNFFRMYKKLSGMTGTAKTEEEEFREIYNMQ
VITIPTNRPIARKDMPDILYPTLDSKFHAVVEEIKKRHANGQPVLVGTVAIESSERLSHLLDEAGIPHAVLNAKNHAKEA
QIIMNAGQRGAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGYTRFYLSLEDDLMKR
FGGDRVKDFLDRLSDNDDDKVIESRLITRQVESAQKRVEGNNYDIRKQTLQYDDVMRIQREIIYGERMQVIDADKSLKNV
LIPMIHRTIDSQVDMFTQGDRSEWRLDSLRDFISSSLTSEQVTDSIDFKTISVEDLKKKLYDIVEKNFEDKEKALGDPSQ
MLEFEKVVILRVVDDRWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQDSGYRMFEEMISNIEFDVTRLFMKAEIRQNISR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-137 42