Gene Information

Name : smpB (lhv_0473)
Accession : YP_001576971.1
Strain : Lactobacillus helveticus DPC 4571
Genome accession: NC_010080
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 467147 - 467605 bp
Length : 459 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAAGAAAGAAAAAGATGATAATTTAATCGCGCAAAATAAAAAAGCGCGGCATGATTATTTTATTAAGGAGACCGTTGA
AGCAGGAATTGCATTAACTGGAACTGAAATAAAATCTGTTCGTGCGCGTAGAATAAACTTGCGTGATGGATATGTTCAAA
TTTATGGTGGCTCTGCTTATTTAGAGAACGTTCATATTAGTGAATATAAACAAGGAAATCGTTATAATCATGATCCTTTG
AGAAGTAGACGTCTTCTTTTACATAAAAAGGAAATTGCACGTCTTGCAAAGGCGCAGTCTGAACGTGGAATAGCTATTAT
TCCATTAAAGGTTTATTTGAAGCATGGTTTTGCCAAAGTTTTGATAGGTGTAGGACAAGGTAAAAAAGAATACGACAAGC
GTCAAACAATCAAAGAACGAGATCAAAAACGTGAAATTCGCCGCAAATATGGTATTTAG

Protein sequence :
MKKEKDDNLIAQNKKARHDYFIKETVEAGIALTGTEIKSVRARRINLRDGYVQIYGGSAYLENVHISEYKQGNRYNHDPL
RSRRLLLHKKEIARLAKAQSERGIAIIPLKVYLKHGFAKVLIGVGQGKKEYDKRQTIKERDQKREIRRKYGI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-38 59
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 4e-25 42