Gene Information

Name : lhv_0301 (lhv_0301)
Accession : YP_001576819.1
Strain : Lactobacillus helveticus DPC 4571
Genome accession: NC_010080
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 308436 - 310916 bp
Length : 2481 bp
Strand : +
Note : -

DNA sequence :
ATGGAAAATTCATATAGTAAAAGCGCTAATCAAGTGTTAGAAATTGCGCGTGAACAAGCACAGGAGTTTCATCATCGGCT
AATTGGTACTGAGCATGTGTTATTGGCTATGGTGATTGAAACTGAAGGTGAAGCAGGAAAAATCTTGCGCTCATGGGGAT
TGACGCCAACTGCCGTACGAGAAGAGATTGAACGTTACACAGGCTATGGTTCAGCAGCTAAGTCAAGCTACATGGAAATG
TCACCTCGTTTAAGCTTAGCGTTAGATTATGCCAAAAGACAGGCTGACCAAGGTGGATATAAAGAAATTGAAACTAATCA
TGTTTTGCTAGGAATAACTGCTAGTGAACAGGTTTTGTCAGCCATGATTTTAAAGAACTTAAATGTTGATATTGGCCGTT
TGCGTCAAGATATTAATGACAGCTTGGATCAAGAACAAGACTTTGGCGATTCAGCAAGCTGGTTAGGCAATAGCAATACC
GCTACTAGCCAAAAGAAACGTAAAAATAGTACTACACCAACTCTAGATAAAGTAGCGGTTAATTTAAATCAACGCACCCG
TGAAGGTGGAATTGATCCAGTTATTGGCCGTGAAAAAGAAATTAAGCGAGTTATTCAAATTTTATCTCGTCGTACTAAGA
ACAATCCAATTTTGGTAGGCGAACCTGGTGTAGGTAAAACTGCGGTCGCCGAAGCAATTGCTACAGAAATTGTTAATAAA
AAAGTTCCAGAAGGCTTGCTTGATAAGCGAGTAATGGCTCTTAACATGGGCAGTTTAGTAGCAGGCACTAAGTATCGTGG
TGAATTTGAAGATAGAATGAAAAAGATTTTGGATGAAATTGCCAAAGACGGTAAAGTCATTCTATTTGTCGATGAAATGC
ATACTTTGATTGGTGCTGGTGGTGCTGAAGGGGCAATTGATGCTTCTAATATTTTGAAACCTTCACTTGCGCGCGGCGAT
ATTCAAATGATTGGTGCTACTACATTTGATGAATATCAAAAGTACATTGAAAAGGATCAAGCATTGGCTCGTCGTTTCCA
ACAAGTACGTTTGAATGAACCTACTAAGAAGGATACGTTAGCTATTTTAAAGGGACTTAGACCTAAGTATGAAAAGTTCC
ACCATGTGACTATTTCAGATGCTAGTCTTGAGGATGCTGTTGATTTATCTAGTCGGTACATTACTAATCGGTTCTTGCCA
GATAAGGCGATTGATTTGGTAGATGAGGCTAGTGCAGCAGTTAAAATTAGAACTAATGTTGGTTCAAACAAAGATTTAGT
TCAAATTAATGAAAAGATAAAGAATATTATTGAACAAAAGAATGAAGCAGCTGCGAGTCAGAACTTTGTTAAAGCAGCTC
AACTTCAAGAAGCACAAAACAATTTGCAAATGCAGCGAGAAGAAATGGAGAATGCATTGCAAGTTAAGGCTAGTGCTGAG
GCTGTTGTTGGCCCTGAAGATATTGCCGAGGTAGTATCTGACTGGACAGGTGTACCTGTTACTCAGATGAAGAGGGATGA
AAGTCGCCAATTAGCTAACTTAGAGAGCATTTTGCATAAACGCGTGATTGGGCAAGATAAGGCTGTTTCAGCTGTAGCTC
GTGCAATTCATCGTAGCAGAAGCGGTATTAAGGATGAGCGCCGTCCAATTGGATCATTCTTGTTCTTAGGGCCAACAGGT
GTAGGTAAGACTGAATTAGCTAAATCAGTTGCAGCAGCAATGTTTGGGTCAGAAGATAATTTGATCAGATTAGATATGTC
TGAGTACATGGATCAAATTGCCTCAAGCAAGTTAATTGGCTCAGCTCCTGGTTATGTTGGCTATGAAGAGGGCGGACAAC
TTTCTGAACAAGTTCGTCGTCATCCATATTCAGTTGTTTTGCTTGATGAAGTGGAAAAAGCTCATCCTGATGTATTTAAT
TTGCTTTTGCAAGTTTTGGATGAAGGATTTTTGACAGATTCTAAAGGCAGAAAAGTCGACTTTAGAAATACAATCATCAT
TATGACTTCTAATTTGGGTTCACGTACGTTATTTGACAGCAAGGCTGTAGGTTTCAATGCTGATAAGGTTGACCAAGCTA
AAGTAAGACAAGTTAAAGTTCAACAGGCAATTAAGCAATTCTTCCGTCCGGAATTTTTGAACCGAATTGATGAAACGATT
ATCTTTGATGAATTAACTAAGAAGCAGTTGCGGGACATTGTAACTTTACTTACTCACAAGTTGGTAGTTCGTTTGCAAAA
GAAGGGAATTACGCTTAGGATTTCCCGTGCCGCTTTGGATAAAATTGTTAAAGATGGTTATGACCCTGAAAATGGTGCTC
GTCCACTTAGAAGAGCAATCCAAAATGATATCGAAGATAAATTAGCAGAAATGTTGATTACAGGTGAAGTAAAAGCAAAC
GACACTTTGAAAATTGGTAGTCAACATGGTCATTTGAAATTTGATGTTGTGCCAGAGAAAAAACTGGTGAAAACTAAGTA
A

Protein sequence :
MENSYSKSANQVLEIAREQAQEFHHRLIGTEHVLLAMVIETEGEAGKILRSWGLTPTAVREEIERYTGYGSAAKSSYMEM
SPRLSLALDYAKRQADQGGYKEIETNHVLLGITASEQVLSAMILKNLNVDIGRLRQDINDSLDQEQDFGDSASWLGNSNT
ATSQKKRKNSTTPTLDKVAVNLNQRTREGGIDPVIGREKEIKRVIQILSRRTKNNPILVGEPGVGKTAVAEAIATEIVNK
KVPEGLLDKRVMALNMGSLVAGTKYRGEFEDRMKKILDEIAKDGKVILFVDEMHTLIGAGGAEGAIDASNILKPSLARGD
IQMIGATTFDEYQKYIEKDQALARRFQQVRLNEPTKKDTLAILKGLRPKYEKFHHVTISDASLEDAVDLSSRYITNRFLP
DKAIDLVDEASAAVKIRTNVGSNKDLVQINEKIKNIIEQKNEAAASQNFVKAAQLQEAQNNLQMQREEMENALQVKASAE
AVVGPEDIAEVVSDWTGVPVTQMKRDESRQLANLESILHKRVIGQDKAVSAVARAIHRSRSGIKDERRPIGSFLFLGPTG
VGKTELAKSVAAAMFGSEDNLIRLDMSEYMDQIASSKLIGSAPGYVGYEEGGQLSEQVRRHPYSVVLLDEVEKAHPDVFN
LLLQVLDEGFLTDSKGRKVDFRNTIIIMTSNLGSRTLFDSKAVGFNADKVDQAKVRQVKVQQAIKQFFRPEFLNRIDETI
IFDELTKKQLRDIVTLLTHKLVVRLQKKGITLRISRAALDKIVKDGYDPENGARPLRRAIQNDIEDKLAEMLITGEVKAN
DTLKIGSQHGHLKFDVVPEKKLVKTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-169 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lhv_0301 YP_001576819.1 ATP-dependent Clp protease VFG0079 Protein 0.0 51
lhv_0301 YP_001576819.1 ATP-dependent Clp protease VFG0080 Protein 8e-140 48